专利号:US-11560357-B2 优先权日:2018-09-22 标题 :Methods of producing pyrazole compounds 发明人:GUPTA RAMESH CHANDRA; SINGARAVEL MOHAN; CHHIPA LAXMIKANT; KASUNDRA ASHOK 权利人:TORRENT PHARMACEUTICALS LTD 摘要:The present invention is directed to methods of producing substituted pyrazole based compounds through novel intermediates and unique processes for preparing such intermediates which enables synthesis of final product through commercially viable route of synthesis. The present invention is also directed to novel methods of producing substituted pyrazole based thyroid like compounds, and solid forms of 3-{4-[(7-hydroxy-6-methyl-indan-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-propanoic acid, its pharmaceutical compositions, and methods of preparation thereof.
专利号:US-7879935-B2 优先权日:2004-06-07 标 题 :Synthesis of nanoparticles in non-aqueous polymer solutions and product 发明人:LALGUDI S RAMANATHAN; VIJAYENDRAN BHIMA R; SCHULTE MICHAEL D; HARDAKER STEPHEN S; GUPTA ABHISHEK; ELHARD JOEL D 权利人:BATTELLE MEMORIAL INSTITUTE 摘要:The invention provides for production of nanoparticles dispersed in polymers where the nanoparticles include metals and metal oxides/sulfides that provide enhanced properties (e.g. higher refractive index) to the material. The nanoparticles are typically formed in situ within the polymer. Typically the nanoparticles are in the form of nanocrystals.
专利号:US-5807834-A 优先权日:1994-09-20 标 题 :Combination of a cholesterol absorption inhibitor and a cholesterol synthesis inhibitor 发明人:MOREHOUSE LEE A 权利人:PFIZER 摘要:PCT No. PCT/IB95/00447 Sec. 371 Date Mar. 18, 1997 Sec. 102(e) Date Mar. 18, 1997 PCT Filed Jun. 7, 1995 PCT Pub. No. WO96/09827 PCT Pub. Date Apr. 4, 1996Pharmaceutical combination compositions including certain cholesterol absorption inhibitors and cholesterol synthesis inhibitors. The compositions are useful for the treatment of hypercholesterolemia and atherosclerosis.
专利号:US-2011230343-A1 优先权日:2008-10-24 标题 :Method for the Manufacture of Microparticles Comprising an Effect Substance 发明人:SCHROERS MICHAEL; DYLLICK-BRENZINGER RAINER; MERK MICHAEL; BARG HEIKO 权利人:BASF SE 摘要:A subject matter of the present invention is a process for the preparation of effect compound-comprising microparticles M comprising A) the formation of a crude suspension of microparticles A by means of enzymatic polyester synthesis in an inverse miniemulsion comprising enzyme, effect compound and polyester monomers; and B) the polymerization of wall monomers from the group consisting of ethylenically unsaturated monomers, polyisocyanates and polyepoxides in the crude suspension of microparticles A. Furthermore, the present invention relates to microparticles M which can be obtained by means of the process according to the invention and also to an agrochemical formulation comprising microparticles M. In addition, the present invention relates to the use of microparticles M prepared according to the invention as component in colorants, cosmetics, drugs, biocides, plant protection agents, fertilizers, additives for food or animal fodder, or auxiliaries for polymers, paper, textiles, leather, detergents or cleaners. Finally, the invention also relates to a method for combating undesirable plant growth, to a method for combating undesirable insect or acarid infestation on plants and/or for combating phytopathogenic fungi, and to seeds treated with the agrochemical formulation.
专利号:US-2007293611-A1 优先权日:2004-06-07 标 题 :Synthesis of Nanoparticles in Non-Aqueous Polymer Solutions and Product
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合成参考文献
参考文献:10.1038/s41428-023-00761-0 摘要:Miyashita T, Saito H. Crystal polymorphism of poly(vinylidene fluoride) blended with alkylammonium salts exhibiting different ion-dipole interaction strengths. Polym J. 2023 Feb 13;55(6):711–5. doi: 10.1038/s41428-023-00761-0.