CAS: 69630-50-8; H-D-Asp(Ome)-Ome.Hcl

相似化合物

14358-33-9 32213-95-9 55747-84-7

上下游产品

dimethyl (S)-malate methanol (2R)-aspartic acid chloro-trimethyl-silanedimethyl (R)-N-(triphenylmethyl)aspartate Dimethyl D-N-benzylaspartate (2R)-2-tert-butoxycarbonylamino-succinic acid dimethyl ester dimethyl N-tert-butoxycarbonyl-L-aspartate

L-苹果酸二甲酯 反应生成 L-天冬氨酸二甲酯盐酸盐,D-天冬氨酸二甲酯盐酸盐
参考文献:高光学纯度的n-羟基-α-氨基酸衍生物的有效合成
标题:高光学纯度的n-羟基-α-氨基酸衍生物的有效合成
摘要:通过三氟甲磺酸酯将α-羟基酯转化为化合物3的化学收率范围为78%至89%,光学纯度范围为76%至100%.
DOI:10.1016/s0040-4039(00)95329-2

专利信息

专利号:WO-9324518-A1
优先权日:1992-05-28
标 题 :Design and synthesis of a cd4 beta-turn mimetic for inhibiting the binding of hiv gp120
发明人：KAHN MICHAEL
权利人:UNIV ILLINOIS
摘要:The invention provides materials and methods for synthesizing novel beta-turn mimetics, as well as the novel beta-turn mimetics themselves, and peptides containing the same. The invention specifically provides beta-turn mimetics that are inhibitors of the binding of HIV gp120 to amino acid residues 40-45 of human CD4, and mimetics of the CDR3 like region involved in syncytial formation.

专利号:US-5556990-A
优先权日:1994-12-16
标 题:Polyarylcarbamoylaza- and -carbamoylalkanedioic acids
发明人：PAULS HENRY W; CHOI YONG-MI; STUDT ROBERT W; MAGUIRE MARTIN P; SPADA ALFRED P; CHA DON D
权利人:RHONE POULENC RORER PHARMA
摘要:This invention relates to a class of novel dicarboxy amide derivatives of lipophilic amines which exhibit squalene synthase inhibition properties. More specifically the compounds are bis-aryl and/or heteroaryl alkyl or cycloalkylamino dicarboxy amides. Compounds of this invention reduce levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention.