CAS: 893-33-4; 4,4,4-Trifluoro-1-(Naphthalen-2-yl)Butane-1,3-Dione

相似化合物

13298-50-5 1800-42-6 98386-82-4

上下游产品

CAS号383-63-1 三氟乙酸乙酯 | CAS号93-08-3 2-萘乙酮 | CAS号431-47-0 三氟乙酸甲酯(TFAM) | CAS号4452-06-6 2-萘乙烯基酮

1,1,1-三氟-4-甲氧基-4-(萘-2-基)丁-3-烯-2-酮置于硫酸体系中,用 水 作为反应溶剂,化学反应 16.0H,以74%的收率获得产物4,4,4-三氟-1-2-萘-1,3-丁烷二酮
参考文献:合成1-叔丁基-3(5)-三氟甲基-1H-吡唑的区域选择性和反应介质的比较研究
标题:合成1-叔丁基-3(5)-三氟甲基-1H-吡唑的区域选择性和反应介质的比较研究
摘要:介绍了从 4-烷氧基-1,1,1-三氟-3-烯烃-2 反应合成一系列 1-叔丁基-3(5)-(三氟甲基)-1H-吡唑的研究-Ones [cf3C(O)Ch=c(R1)(Or),其中 R = Et 且 R1 = H 或 R = Me 且 R1 = Me,Ph,4-Me-C6H4,4-Meo-C6H4,4-F-C6H4,4-Cl-C6H4,4-Br-C6H4,4-I-C6H4,Fur-2-Yl,Thien-2-Yl或naphth-2-Yl]与叔丁基肼盐酸盐.当[bmim][bf4](1-丁基-3-甲基咪唑四氟硼酸盐)和吡啶用作反应介质时,我们得到了1-叔丁基-3(5)-三氟甲基吡唑的混合物.当反应在乙醇中的 Naoh 中进行时,会形成具有高区域选择性的 5-三氟甲基-1-叔丁基-1H-吡唑.4-烷氧基-1,1水解后,反应生成1-叔丁基-3-三氟甲基-1H-吡唑,
DOI:10.1002/ejoc.201201111

专利信息

专利号:WO-9000622-A1
优先权日:1988-07-08
标题 :Oligonucleotide hybridization probes and means for the synthesis of the most preferred probes
发明人：KWIATKOWSKI MAREK; SUND CHRISTIAN; HURSKAINEN PERTTI
权利人:WALLAC OY; PHARMACIA AB
摘要:Oligonucleotide probe labeled at one of its teminal positions with a non-linear branched polymer carrying a plurality of negatively charged groups, preferably phosphodiester groups, and optionally also analytically indicatable groups covalently linked to terminal ends of the branches of said polymer. The preferred indicatable groups are lanthanide chelates. A compound that can be used for the synthesis of the probe is also disclosed. The compound has formula (I), where R1 and R2 are lower alkyl; R3 is lower alkyl (C1-C7), or aryl each of which optionally being provided with electron-withdrawing substituents; and A1, A2 and A3 are hydrogen, A'-O-B, A''-O-B or A'''-O-B, at most one of A1-3 being hydrogen and A', A'' and A''' being a hydrocarbon chain providing a distance of 5-9 atoms between the phosphorous atom and the oxygen directly bound to B, and B being a protecting group. In the preferred compound at least two of A1-3 are identical while the other is hydrogen.

专利号:US-3966818-A
优先权日:1972-03-25
标 题 :Novel process for preparation of 4-hydroxy-2,4,6-trimethyl-2,5-cyclohexadiene-1-one
发明人：ICHIKAWA YATARO; YAMANAKA YOSHIYUKI; TSURUTA HIDEKI
权利人:TEIJIN LTD
摘要:A process for preparing 4-hydroxy-2,4,6-trimethyl-2,5-cyclohexadiene-1-one comprising reacting 2,4,6-trimethyl phenol with molecular oxygen or a molecular oxygen-containing gas. The product (also called mesitylquinol) is an intermediate useful as a raw material for the synthesis of a variety of industrial chemicals such as a drugs, dyestuffs, and pigments.

专利号:US-8552163-B2
优先权日:2009-09-25
标题 :Liver-targeting agents and their synthesis
发明人：LEE REIKO TAKASAKA; LEE YUAN-CHUAN; WANG MEI-HUI; LIN WUU-JYH
权利人:LEE REIKO TAKASAKA; LEE YUAN-CHUAN; WANG MEI-HUI; LIN WUU-JYH; UNIV JOHNS HOPKINS; INER AEC EXECUTIVE YUAN
摘要:This invention provides novel liver targeting agents and their synthetic methods. A liver targeting agent, with a lysine based nitrilotriacetic acid structure as backbone which acquires multivalency with saccharide groups, to bind with a galactosamine chain or lactose chain is disclosed. In particular, only one amino acid L-lysine is involved to provide trivalency. All carboxyl groups in N ε -benzyloxycarbonyl-N α -dicarboxymethyl-L-lysine can be conjugated with three glycosides of ahGalNAc or ahLac in one step. This invention also provides a hexa-lactoside. In particular, the TFA-AHA-Asp was used to conjugate 2 molecules of NTA(ahLac) 3 . This invention also provides a method for adding a spacer between NTA and DTPA. The extended hepatocyte-specific glyco-ligand has higher 111 In-radiolabelling yield than those non-extended.

专利号:EP-0378652-A1
优先权日:1988-07-08
标 题 :Oligonucleotide hybridization probes and means for the synthesis of the most preferred probes

专利号:US-6166251-A
优先权日:1996-03-08
标题:Labeled reagents for use in immunoassays and fluorescent compounds and complexes used therein
发明人：MATSUMOTO KAZUKO; YUAN JINGLI
权利人:MATSUMOTO KAZUKO; SUZUKI MOTOR CO
摘要:Disclosed are labeling reagents containing fluorescent compounds represented by the general formula where R is a group capable of combining with proteins, Ar is a conjugated double bond system, and n is a whole number. These labeling reagents have high fluorescence emission intensities, give high synthesis yields, permit both solid-phase measurements and liquid-phase measurements in immunoassays, and require less measuring steps.