CAS: 19806-17-8; 2,2'-(1,3-Phenylene)Diacetic Acid

上下游产品

CAS号626-22-2 1,3-二苯乙氰 | CAS号201230-82-2 carbon monoxide | CAS号626-16-4 间二氯苄 | CAS号108-38-3 间二甲苯 | CAS号67-56-1 甲醇 | CAS号626-15-3 间二溴苄 | CAS号111-65-9 正辛烷 | CAS号1822-71-5 sodium,pentane | CAS号25424-26-4 Ethanedione,1,1... | CAS号36076-20-7 m-Phenylenebis(... | CAS号113520-28-8 2-[3-(2-ethoxy-... | CAS号224-41-9 二苯并(a,j)蒽

1,3-二乙炔苯置于正丁基锂,Oxone||potassium Monopersulfate Triple Salt,水体系中,用 四氢呋喃,正己烷,丙酮 用作溶剂,化学反应 15.0H,反应生成1,3-苯二乙酸
参考文献:炔基硼酸酯氧化成羧酸,酯和酰胺.
标题:炔基硼酸酯氧化成羧酸,酯和酰胺.
摘要:已经开发了一种通用有效的方案,用于通过直接从末端炔烃生成的炔基硼酸酯的氧化来合成羧酸,酯和酰胺.该协议代表c(sp)-B键氧化的第一个例子.该方法显示出广泛的底物范围,包括芳基和烷基炔烃,并且具有出色的官能团耐受性.水,伯醇和仲醇以及胺是适合这种转化的亲核试剂.值得注意的是,氨基酸和肽可用作亲核试剂,为合成和修饰肽提供了一种有效的方法.药物分子的制备进一步强调了该方法的实用性.
Doi:10.1002/anie.202000988

专利信息

专利号:US-10407468-B2
优先权日:2016-03-23
标 题 :Methods for synthesizing α4β7 peptide antagonists
发明人：BHANDARI ASHOK; MANTHATI SURESH KUMAR; MEHROTRA MUKUND M; ANANDAN SAMPATH-KUMAR; PATEL DINESH V
权利人:PROTAGONIST THERAPEUTICS INC
摘要:The present invention provides methods of making α4β7 peptide monomer and dimer antagonists. Methods of the present invention include solid phase and solution phase methods, as well as synthesis via condensation of smaller peptide fragments. Methods of the present invention further include methods directed to the synthesis of peptides comprising one or more penicillamine residues.

专利号:JP-2007513195-A
优先权日:2003-12-24
标题:Synthesis of acylureas and compositions containing acylureas

专利号:WO-2017065980-A1
优先权日:2015-10-13
标题 :Preparation of a sugar-derived ester, glycol and polymers therefrom
发明人：STENSRUD KENNETH; SMITH BRENNAN
权利人:ARCHER DANIELS MIDLAND CO
摘要:Methods for preparing 1) a sugar-derived ester, 2) a glycol generated from reduction of the ester, and 3) polymers fabricated from polycondensation of the ester or glycol with various diamines and dicarboxylic acids are described. In particular, the ester is levulinic 5-methyl-2-furfural (LMF), the acylation product of hydroxymethyl-furfural (HMF) and either a levulinyl halide or levulinic acid. Each of the embodiments for the synthesis is highly selective for the product and can be executed under relatively mild reaction conditions.

专利号:CN-115925790-A
优先权日:2016-03-23
标 题:Method for the synthesis of α4β7 peptide antagonists

专利号:JP-4884233-B2
优先权日:2003-12-24
标 题 :Synthesis of acylureas and compositions containing acylureas

专利号:CN-116284779-A
优先权日:2023-04-23
标题 :Synthesis method of polybenzimidazole polymer