CAS: 3162-29-6; 3',4'-(Methylenedioxy)Acetophenone

该化合物是有机化合物,其独特结构包括苯二氮新诺明和乙酰功能组,该化合物的颜色一般视其纯度和形态而显得无色,淡黄色液体或固体,因其芳香性能而闻名,有助于其在香味和口味行业的潜在应用;乙酰组的存在,加强了其再活动,使其成为有机合成的有用中间体;此外,5-乙酰1,3-苯二氧可展示生物活动,引起对药用化学的兴趣;乙醇和醚等有机溶剂的溶性,允许多种化学反应的多功能性;然而,与许多有机化合物一样,应谨慎处理该化合物,并遵守因潜在毒性或刺激性特性而产生的适当安全规程.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

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合成工艺路线路线简述

  • 合成目标产物 3,4-Methylenedioxyacetophenone 主要起始原料 1,3-Benzodioxole And Acetic Acid
  • (文献来源)合成步骤主要原料 1,3-Benzodioxole 和 Acetic Acid
3-(6-胡椒环基)-3-氧代丙酸乙酯置于硫酸体系中,化学反应生成3,4-亚甲二氧苯乙酮
参考文献:Shriner; Kleiderer,Journal Of The American Chemical Society,1929,Vol. 51,P. 1269
标题:Shriner; Kleiderer,Journal Of The American Chemical Society,1929,Vol. 51,P. 1269

海关参考信息

专利信息


专利号:WO-2025075817-A1
优先权日:2023-10-02
标 题 :Methods for synthesis of protein hetero-polymers
发明人:SHRADER ALANNA SCHEPARTZ; ROE LEAH TANG
权利人:UNIV CALIFORNIA
摘要:A method for synthesis of protein hetero-polymers uses an intramolecular Backbone Extension Acyl Rearrangement (BEAR) reactions to orthogonally and site-specifically embed a β-, γ- or δ-amino acid residue into proteins.

专利号:US-2009143426-A1
优先权日:2007-12-04
标 题:Synthesis of 1,3,6-trisubstituted-2-carboxyquinol-4-ones as selective ET A antagonists and their use as medicaments
发明人:STEPHANI RALPH ANTHONY; PATEL HARDIK JITENDRA; REZNIK SANDRA EVE; CANTOR JEROME OWEN
权利人:STEPHANI RALPH ANTHONY; PATEL HARDIK JITENDRA; REZNIK SANDRA EVE; CANTOR JEROME OWEN
摘要:The invention discloses the composition and preparation of various 1,3,6-trisubstituted-2-carboxy-quinol-4-ones of the formula 1 where R is H, alkyl, haloalkyl or hydroxyalkyl, R′ is alkyl, nitro, halogen or NR 2 ′″ where R′″ is alkyl or cycloalkyl, and R″ is H or alkyl. The composition of the invented compounds as methods of antagonizing the action of endothelin-1 to treat cardiovascular, pulmonary diseases and obstetric disorders and preterm labor and preeclampsia in mammals is disclosed.

专利号:US-9328061-B2
优先权日:2012-03-01
标题:Simple organic molecules as catalysts for practical and efficient enantioselective synthesis of amines and alcohols
发明人:HOVEYDA AMIR H; SILVERIO DANIEL L; PILYUGINA TATIANA; TORKER SEBASTIAN; ROBBINS DANIEL
权利人:TRUSTEES BOSTON COLLEGE
摘要:The present invention provides organic molecules and methods thereof for reactions between organoboron reagents and double bonds, such as imines or carbonyls, to stereoselectively provide chiral products including amines and alcohols, entities useful for the preparation of biologically active molecules.

专利号:US-9006231-B2
优先权日:2008-03-03
标 题:Cephalotaxus esters, methods of synthesis, and uses thereof
发明人:GIN DAVID Y; WILMOT JEREMY; DJABALLAH HAKIM
权利人:SLOAN KETTERING INST CANCER
摘要:The present invention provides novel cephalotaxus esters, syntheses thereof, and intermediates thereto. The invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of using said compounds or compositions in the treatment of proliferative diseases (e.g., benign neoplasm, cancer, inflammatory disease, autoimmune disease, diabetic retinopathy) and infectious disease. The invention further provides methods of using said compounds or compositions in the treatment of multidrug resistant cancer.

专利号:US-6005103-A
优先权日:1993-11-19
标题 :Pyrone derivatives as protease inhibitors and antiviral agents
发明人:DOMAGALA JOHN MICHAEL; LUNNEY ELIZABETH; PARA KIMBERLY SUZANNE; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
权利人:WARNER LAMBERT CO
摘要:The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.

专利号:US-8563590-B2
优先权日:2008-03-05
标 题 :Compounds, compositions and methods for the treatment of islet amyloid polypeptide (IAPP) accumulation in diabetes
发明人:LAKE THOMAS; SNOW ALAN D
权利人:LAKE THOMAS; SNOW ALAN D; PROTEOTECH INC
摘要:Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of IAPP or amylin fibril diseases, and the manufacture of medicaments for such treatment.
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合成参考文献


摘要:Hall, D. G.; Zheng, H., Science of Synthesis Knowledge Updates, (2011) 4, 100.
摘要:Singh, F. V., Science of Synthesis Knowledge Updates, (2021) 1, 154.
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
摘要:Li, J. J., Science of Synthesis: Knowledge Updates, (2025) 2.
摘要:Kwiatkowska, M.; Kiełbasiński, P., Science of Synthesis: Knowledge Updates, (2024) 3, 437.
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