CAS: 1074-36-8; 4-Mercaptobenzoic Acid

该化合物是一种有机化合物,其特点是一种苯并酸结构,其含硫醇(-SH)组,该组位于与碳酸(-COOH)组相对的par 位置,其特点是白色到浅黄色晶状表面,由于硫醇组的存在,该组具有独特的气味;它溶于水和酒精等极地溶剂中,而非冰溶剂中的溶解性较低;氨酸和硫醇功能组的存在都具有独特的化学反应性,使其在各种应用中,包括在其他有机化合物合成中的消毒剂,以及在金属硫化纳米粒子的制作中有用.此外,4-甲基苯甲酸可以参与各种化学反应,例如酯化和硫酸反应,并经常用于材料科学和生物化学化学化学学中,以形成表面的单体.

结构式图片

相似化合物

36801-01-1 6302-65-4 53339-53-0

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号619-58-9 对碘苯甲酸 | CAS号24197-62-4 4-acetylsulfany... | CAS号140-89-6 乙基黄原酸钾 | CAS号150-13-0 对氨基苯甲酸 | CAS号13511-93-8 methyl 4-(dimet... | CAS号1155-51-7 4,4'-二硫二苯甲酸 | CAS号106-53-6 4-溴苯硫酚 | CAS号10130-89-9 4-氯磺酰基苯甲酸 | CAS号35190-68-2 双(对苯甲酸甲酯)二硫化物 | CAS号586-76-5 对溴苯甲酸 | CAS号35190-68-2 双(对苯甲酸甲酯)二硫化物 | CAS号13205-48-6 4-甲硫基苯甲酸 | CAS号3795-79-7 4-(甲基硫代)苯甲酸甲酯 | CAS号22855-95-4 Benzoic acid,4-... | CAS号24197-62-4 4-acetylsulfany... | CAS号28276-32-6 ethyl 4-sulfany... | CAS号6302-65-4 对硫氢基苯甲酸甲酯 | CAS号7748-20-1 4,4'-二硫二基双(4,1-... | CAS号53339-53-0 4-巯基苯甲醇 | CAS号13205-49-7 4-(乙硫基)苯甲酸

合成工艺路线路线简述

    4,4'-二硫二苯甲酸置于溶剂黄146,锌体系中,化学反应 4.0H,以38%的收率获得4-巯基苯甲酸
    参考文献:叶酸拮抗剂.17.合成和氨基蝶呤的2,4-二氨基-6-Thioquinazoline类似物的生物特性†
    标题:叶酸拮抗剂.17.合成和氨基蝶呤的2,4-二氨基-6-Thioquinazoline类似物的生物特性†
    摘要:由4-巯基苯甲酸和5-氯-2-硝基苄腈合成n-[4-[(2,4-二氨基-6-喹唑啉基)硫代]苯甲酰基]-L-谷氨酸(2)的多步路线是描述.尽管该氨基蝶呤类似物缺乏显着的抗疟活性,但它是来自克鲁斯锥虫的二氢叶酸还原酶的有效抑制剂.然而,蝶呤酯类似物11在高剂量下对小鼠伯氏疟原虫感染具有活性.
    Doi:10.1002/jhet.5570170315

    海关参考信息

    专利信息


    专利号:US-10150160-B2
    优先权日:2014-12-04
    标题 :Universal one-pot and up-scalable synthesis of SERS encoded nanoparticles
    发明人:PAZOS PÉREZ NICOLÃ?S; MIR DE SIMÓN BERNAT
    权利人:MEDCOM ADVANCE S A; MEDCOM ADVANCE S A
    摘要:The universal one-pot and up-scalable synthesis of SERS encoded nanoparticles relies on the controlled co-absorption of mercaptoundecanoic acid (MUA) and the Raman code on the metallic surfaces of the nanoparticles. In contrast to most of the reported procedures which typically involve complex steps, the present method has demonstrated to be an easy and fast one-pot approach for the production of SERS-encoded nanoparticles. This versatile strategy allows for the SERS codification of particles with every molecule with affinity toward the metal surface, independently of its chemical nature, as exemplified here in the fabrication of 31 different encoded particles using the same standard procedure. In addition to the easiness of preparation, scalability to the liter regime, stability in aqueous solutions including PBS and chemical diversity, our SERS-encoded particles show considerably higher optical efficiency than those fabricated by using PEG or PVP polymers.

    专利号:US-2003232952-A1
    优先权日:2001-02-02
    标题:Design and synthesis of instant - degradable plastics
    发明人:ROSEN OREN
    摘要:A novel class of instant degradable synthetic polymeric plastics having the characteristics and properties of conventional forms of plastics is developed by providing a new application advantage of incorporating latent, labile, dormant chemical bond nuclei such as disulfide and sulfenyl derivatives of the plastic compounds with latent nucleophilic properties. The special advantage of the instant degradable polymers over the existing biodegradable and other degradable polymer counterparts, is their engineering and design, which makes the kinetics of their degradation instant, and the chemical and physical properties of their by-products allows soluble dissolution into non-toxic aqueous solvent media, thus enabling a practical treatment of waste and avoiding bio-hazardous pollution of the environment. These novel plastic products are made from a variety of compositions of polymers and their compatible nontoxic modifiers. The resulting novel instant degradable plastic products retain latent dormant solubility properties that are triggered upon mild chemical reaction, thus enabling cost effective and facile recycling of plastic refuge.

    专利号:US-2017304902-A1
    优先权日:2016-04-22
    标题:Synthesis of water-soluble thiolate-protected gold nanoparticles of uniform size and conjugates thereof
    发明人:AZUBEL MAIA; KORNBERG ROGER D
    权利人:UNIV LELAND STANFORD JUNIOR
    摘要:Methods of synthesizing water-soluble thiolate-protected gold nanoparticles of uniform size and conjugates thereof are disclosed. In particular, the invention relates to a method of synthesizing homogeneous, water-soluble gold nanoparticles by using a modified Brust procedure and methods of conjugating them. Gold nanoparticles, produced by the methods of the invention, are useful in various therapeutic and imaging applications where the use of gold nanoparticles having uniform structural and optical properties is desired.

    专利号:US-8673260-B2
    优先权日:2012-01-04
    标 题 :Development of earth-abundant mixed-metal sulfide nanoparticles for use in solar energy conversion
    发明人:PLASS KATHERINE
    权利人:FRANKLIN AND MARSHALL COLLEGE
    摘要:This invention relates to a process for the phase-controlled synthesis of ternary and quaternary mixed-metal sulfide nanoparticles by reacting soft metal ions with hard metal ions in a high-boiling organic solvent in the presence of a complexing and activating ligands to control the reactivity of the metal ions. Ternary and quaternary mixed metal sulfides nanoparticles of copper, sulfur, and iron, aluminum, tin, and silicon are preferred. This invention also relates to the phase controlled preparation of polymorphs of bornite nanoparticles and the phase controlled preparation of stabilized α- and γ-chalconite nanoparticles.

    专利号:US-2014371418-A1
    优先权日:2012-01-05
    标 题 :Biological synthesis of p-aminobenzoic acid, p-aminophenol, n-(4-hydroxyphenyl)ethanamide and derivatives thereof
    发明人:NG WING ON; WATANABE SHINGO; HUMPHREYS ROBERT W R; SLATER STEVEN C
    权利人:PAROMATICS LLC
    摘要:The invention generally relates to biological engineering of microorganisms and production of chemical compounds therefrom. More particularly, the invention relates to novel genetically engineered microorganisms for the fermentative production of p-aminobenzoic acid and related compounds from fermentable carbon substrates. The biologically derived PABA and related compounds from fermentable carbon substrates can be used in a number of applications including as a food supplement or raw materials for the syntheses of other industrial chemicals or polymers.

    专利号:US-10851469-B2
    优先权日:2016-10-13
    标题:Synthesis of core-shell nanoparticles and applications of said nanoparticles for surface enhanced Raman scattering
    发明人:HAIDAR ISRAA; NEUVILLE DANIEL; BOUBEKEUR LEILA; FELIDJ NORDIN
    权利人:UNIV PARIS DIDEROT; CENTRE NAT RECH SCIENT; INST DE PHYSIQUE DU GLOBE DE PARIS
    摘要:A method of synthesizing of gold-silver core-shell nanoparticles, from a colloidal aqueous solution of gold seeds with surfactant, the gold-silver core-shell nanoparticles being produced from anisotropic gold seeds, said method comprising adding to the colloidal aqueous solution a precursor of silver and a reducing agent, to produce the deposition of silver on the gold seeds in a step called principal, characterized in that the method has an incubation step of the colloidal aqueous solution containing the gold seeds with surfactant in the DMSO, prior to the principal step.
    杭州澳立盛化学有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.aolisenchemical.com
    企业联系电话:0571-81727727;15267468089👤
    📞杭州澳立盛化学有限公司 ⚠️参考联系方式
    联系人:罗先生
    电话:0571-81727727;15267468089
    手机:15267468089

    邮箱:sales@aolisenchemical.com
    通信地址: 浙江省杭州市下城区凤起路334号1303室
    邮编:
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:浙江省杭州市下城区凤起路334号1303室
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    杭州鼎燕化工有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.dingyanchem.com
    企业联系电话:18267553885👤
    📞杭州鼎燕化工有限公司 ⚠️参考联系方式
    联系人:林女士
    电话:18267553885
    手机:18267553885
    传真:0571-87156470
    邮箱:sales@dingyanchem.com
    通信地址: 杭州市江干区下沙19号大街571号下沙电子商务园4A601-602室
    邮编: 310018
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:杭州市江干区下沙19号大街571号下沙电子商务园4A601-602室
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    北京世纪裕立化学有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.richapchem.com
    企业联系电话:010-64446226,64455497👤
    📞北京世纪裕立化学有限公司 ⚠️参考联系方式
    联系人:刘经理
    电话:010-64446226,64455497

    传真:010-64455595
    邮箱:info@bj-newcenturychem.com
    通信地址: 北京市海淀区北三环西路32号恒润国际大厦1903室
    邮编: 100086
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:北京市海淀区北三环西路32号恒润国际大厦1903室
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    浙江扬帆新材料股份有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.shoufu.cn
    企业联系电话:0571-88902507;0571-88902517;0571-88902509👤
    📞浙江扬帆新材料股份有限公司 ⚠️参考联系方式
    联系人:唐小姐
    电话:0571-88902507;0571-88902517;0571-88902509

    传真:0571-88902500
    邮箱:shoufu@shoufuchem.com
    通信地址: 浙江省杭州市滨江区信诚路31号扬帆创业大厦
    邮编: 310051
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:浙江省杭州市滨江区信诚路31号扬帆创业大厦
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    第 1 / 1 页

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Alif Chebbi, Et Al. Biodegradation Of Malodorous Thiols By A Brevibacillus Sp. Strain Isolated From A Tunisian Phosphate Factory. Fems Microbiol Lett. 2015 Jul;362(14):Fnv097.
    [参考文献]: Ana B Serrano-Montes, Et Al. A General Method For Solvent Exchange Of Plasmonic Nanoparticles And Self-Assembly Into Sers-Active Monolayers. Langmuir. 2015 Aug 25;31(33):9205-13.
    [参考文献]: Chongwen Wang, Et Al. Polyethylenimine-Interlayered Core-Shell-Satellite 3D Magnetic Microspheres As Versatile Sers Substrates. Nanoscale. 2015 Nov 28;7(44):18694-707.
    [参考文献]: Elmira Farrokhtakin, Et Al. Radial Growth Of Plasmon Coupled Gold Nanowires On Colloidal Templates. J Colloid Interface Sci. 2015 Jul 1:449:87-91.
    [参考文献]: Isabel Freitag, Et Al. Differentiation Of Mcf-7 Tumor Cells From Leukocytes And Fibroblast Cells Using Epithelial Cell Adhesion Molecule Targeted Multicore Surface-Enhanced Raman Spectroscopy Labels. J Biomed Opt. 2015 May;20(5):55002.

    合成参考文献


    摘要:Ogawa, C.; Kobayashi, S., Science of Synthesis: Water in Organic Synthesis, (2012) 1, 591.
    摘要:Ruffoni, A.; Leonori, D., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 551.
    摘要:J. P. Danehy and K. N. Parameswaran, J. Chem. Eng. Data 13, 386 (1968).
    摘要:T. H. Fife and S. Milstien, J. Org. Chem. 34, 4007 (1969).
    摘要:R. J. Irving, L. Nelander and I. Wadso, Acta Chem. Scand. 18, 769 (1964).
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知