专利号:EP-0021952-A1 优先权日:1979-06-19 标题:Process for the synthesis of perilla alcohol and of its derivatives
专利号:US-6911318-B2 优先权日:1999-03-03 标 题:Bacterial transglycosylases: assays for monitoring the activity using Lipid II substrate analogs and methods for discovering new antibiotics 发明人:KAHNE SUZANNE WALKER 权利人:UNIV PRINCETON 摘要:This invention provides a direct method for monitoring bacterial transglycosylase activity using labeled substrates produced by chemo-enzymatic synthesis wherein the labels are selected to permit the detection of both polymeric and non-polymeric products simultaneously, either directly or following the separation of product from starting material. The invention promotes the discovery of new antibiotics with activity against bacterial transglycosylases by a) laying the groundwork for structural analysis of purified, active transglycosylase (which permits structure-based design); and b) providing an assay that can be used to screen for inhibitors.
参考文献:10.1007/698_2023_983 摘要:Rocha F, Ratola N, Homem V. Fragrances in the Environment: Properties, Applications, and Emissions. 2023. In: The Handbook of Environmental Chemistry.