CAS: 29838-67-3; (2R,3R)-2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-Trihydroxy-6-Methyltetrahydro-2H-Pyran-2-yl)Oxy)Chroman-4-One

该化合物是从多角形等植物中提取的自然形成的浮质胶质. 该化合物显示出强效抗氧化特性, 表明大量自由的激进清扫活动, 抑制脂重过氧化. 亚司匹林还通过抑制亲氟化酶生产和细胞信号路径, 表现出抗炎效应 .

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欧盟法规

ECHA物质C&L通报

上下游产品

CAS号294203-79-5 (2R,3R)-5,7-bis... | CAS号20728-73-8 5,7,3',4'-四-O-苄基儿茶素 | CAS号80152-99-4 1-O-acetyl-2,3,... | CAS号104495-20-7 6-deoxy-2,3,4-t... | CAS号294203-76-2 (2R,3S)-5,7-bis... | CAS号294203-78-4 (2R,3S,4S)-5,7-... | CAS号480-18-2 花旗松素

合成工艺路线路线简述

    (2R,3S)-5,7-二(苄氧基)-2-[3,4-二(苄氧基)苯基]-3-色满醇置于钯 重铬酸吡啶,二氯二茂铪,氢气,Silver Trifluoromethanesulfonate,2,3-二氯-5,6-二氰基-1,4-苯醌体系中,用 甲醇,二氯甲烷,水 用作溶剂,化学反应 26.0H,反应生成落新妇苷
    参考文献:First Synthesis Of Astilbin,Biologically Active Glycosyl Flavonoid Isolated From Chinese Folk Medicine
    标题:First Synthesis Of Astilbin,Biologically Active Glycosyl Flavonoid Isolated From Chinese Folk Medicine
    摘要:A Synthetic Route To A Biologically Active Glycosyl Flavonoid,Astilbin (1),Was Developed. The Tetra-Benzyl Ether 4,Derived From (+)-Catechin,Was Glycosylated With The L-Rhamnosyl Donor 10 By Using Cp2Hfcl2Agclo4,And Subsequent Oxidation Of The C(4) Position Of The Flavan Skeleton Followed By Deprotection Gave 1. (C) 2000 Elsevier Science Ltd. All Rights Reserved.
    Doi:10.1016/s0040-4039(00)00826-1

    海关参考信息

    专利信息


    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

    专利号:US-2007036742-A1
    优先权日:2005-08-09
    标题 :Methods and compositions for modulating hair growth or regrowth
    发明人:ROUFS JAMES B; DUVEL LANE A; FAST DAVID J; GLYNN KELLY M
    权利人:ACCESS BUSINESS GROUP INT LLC
    摘要:The present invention relates to compositions and methods for modulating hair growth or regrowth. The compositions of the present invention comprise extracts of one or more of the following: Boswellia serrata, Undaria pinnatifida, green tea (e.g., Camellia sinensis ), shiso, Pureraria mirifica, luteolin (e.g. Perilla ocymoides leaf extract), astilbin, vitamin E, amentoflavone, tetrahydropiperine, licochalcone, astaxanthin, red clover, Brassica juncea, unfermented green rooibos, enzyme CoQ10, salvia, ximenynic acid, hops oleoresin, apple, soy, saw palmetto, or ellagic extract, or any derivative thereof. In particular, the compositions and methods of the present invention can be used to stimulate or increase hair growth and/or prevent or slow the loss of hair by having one or more of the following functions: (a) inhibiting synthesis of DHT; (b) inhibiting proteasomal activity; (c) inhibiting IL-1 activity; (d) increasing vascularization; (e) increasing expression of vascular endothelial growth factor; (f) increasing expression of keratinocyte growth factor; (g) inhibiting inflammation; or (h) acting as an antibacterial.

    专利号:CN-115612114-A
    优先权日:2021-07-14
    标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis
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    主要参考文献


    1: Diao H, Kang Z, Han F, Jiang W. Astilbin protects diabetic rat heart against ischemia-reperfusion injury via blockade of HMGB1-dependent NF-κB signaling pathway. Food Chem Toxicol. 2014 Jan;63:104-10. doi: 10.1016/j.fct.2013.10.045. Epub 2013 Nov 6. doi: 10.1016/j.intimp.2015.12.035. Epub 2016 Jan 16. doi: 10.1016/j.intimp.2016.03.039. Epub 2016 Apr 22. doi: 10.1016/j.bbrc.2014.02.136. Epub 2014 Mar 12. doi: 10.1016/j.jchromb.2013.04.018. Epub 2013 Apr 19. doi: 10.1021/jf404420s. Epub 2013 Nov 25. doi: 10.3390/molecules20010625. doi: 10.1002/bmc.3111. Epub 2014 Jan 7. doi: 10.1371/journal.pone.0124002. eCollection 2015.
    10: Wang M, Zhao J, Zhang N, Chen J. Astilbin improves potassium oxonate-induced hyperuricemia and kidney injury through regulating oxidative stress and inflammation response in mice. Biomed Pharmacother. 2016 Oct;83:975-988. doi: 10.1016/j.biopha.2016.07.025. Epub 2016 Aug 11. doi: 10.1021/jf304398v. Epub 2012 Dec 17. doi: 10.3109/03639045.2012.756008. Epub 2013 Jan 28. Chinese. doi: 10.1055/s-0030-1271135. Epub 2011 May 25. Chinese. doi: 10.1007/s11596-012-0032-8. Epub 2012 Apr 20. Chinese. doi: 10.1016/j.jneuroim.2016.07.016. Epub 2016 Jul 20. Epub 2014 Mar 28.

    合成参考文献


    参考文献:10.1016/j.fct.2011.04.029
    摘要:Huang J, Wang S, Zhu M, Chen J, Zhu X. Effects of genistein, apigenin, quercetin, rutin and astilbin on serum uric acid levels and xanthine oxidase activities in normal and hyperuricemic mice. Food Chem Toxicol. 2011 Sep;49(9):1943–7. doi: 10.1016/j.fct.2011.04.029.
    参考文献:10.1055/s-0030-1271135
    摘要:Chen L, Lan Z, Zhou Y, Li F, Zhang X, Zhang C, Yang Z, Li P. Astilbin attenuates hyperuricemia and ameliorates nephropathy in fructose-induced hyperuricemic rats. Planta Med. 2011 Nov;77(16):1769–73. doi: 10.1055/s-0030-1271135.
    摘要:Zhao RZ, Zhao Y, Zhang LQ, Lu CJ. Determination of isofraxidin and astilbin by HPLC in rat plasma and its application after orally administration the extract of Sarcandra glabra. Pak J Pharm Sci. 2013 Jan;26(1):1–6.
    参考文献:10.1016/j.jep.2006.07.007
    摘要:Kimura Y, Sumiyoshi M, Sakanaka M. Effects of Astilbe thunbergii rhizomes on wound healing Part 1. Isolation of promotional effectors from Astilbe thunbergii rhizomes on burn wound healing. J Ethnopharmacol. 2007 Jan 03;109(1):72–7. doi: 10.1016/j.jep.2006.07.007.
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