CAS: 5538-51-2; 2-(Chlorocarbonyl)Phenyl Acetate

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42926-52-3 21615-34-9 5663-67-2

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CAS号50-78-2 阿司匹林 | CAS号79-37-8 草酰氯 | CAS号579-75-9 邻甲氧基苯甲酸 | CAS号69-72-7 水杨酸 | CAS号493-53-8 sodium O-acetyl... | CAS号10026-13-8 五氯化磷 | CAS号10523-48-5 4-羟基-2-氧代-2H-色烯-3-甲腈 | CAS号107637-99-0 1-benzofuran-3-ol | CAS号55482-89-8 呱西替柳 | CAS号81674-79-5 胍美柳 | CAS号529-68-0 乙酰基水杨酸乙酯 | CAS号410071-22-6 [4-(chloromethy... | CAS号146952-30-9 [2-(hydroxymeth... | CAS号50-78-2 阿司匹林 | CAS号28787-36-2 乙酸麦芽酚酯 | CAS号147249-33-0 Aspalatone

阿司匹林置于氯化亚砜体系中,化学反应 0.5H,反应生成 邻乙酰水杨酰氯
参考文献:新型n-[[[2-(二烷基氨基)乙氧基]苄基]苯甲酰胺衍生物的合成,胃肠道动力学活性和构效关系.
标题:新型n-[[[2-(二烷基氨基)乙氧基]苄基]苯甲酰胺衍生物的合成,胃肠道动力学活性和构效关系.
摘要:合成了新的n-[[[二烷基氨基)乙氧基]苄基]苯甲酰胺衍生物(ii-1-51),该衍生物衍生自甲氧氯普胺(i)的结构修饰,并研究了其药理活性.其中,选择表现出均衡的胃肠道运动和止吐活性的n-[4-[2-(二甲基氨基)乙氧基]苄基]-3,4-二甲氧基苯甲酰胺(ii-34)作为新型胃肠道运动剂.
DOI:10.1248/cpb.40.202

专利信息

专利号:WO-2023129116-A3
优先权日:2021-12-31
标题:A drug for the treatment of type 2 diabetes mellitus disease and the nanoparticle thereof
发明人：AL-GBURI FIRAS SHAWQI ABDULRAZZAQ; TAYSI SEYITHAN; OZDEMIR NALAN; ALI ALI OMEED AKBAR
权利人:GAZIANTEP UNIV REKTORLUGU
摘要:The invention relates to the synthesis methods of a drug and nanoparticle thereof for the treatment of type-2 Diabetes Mellitus disease. The synthesis method of the drug of the invention in its most general form includes synthesis of aspirin chloride (2), synthesis of amide (3) from the aspirin chloride (2) obtained and synthesis of nitrile (4) compound from the amide (3) compound obtained. The synthesis method of the nanoparticle of the drug of the invention includes the process steps of obtaining the nanoparticle (5) by synthesizing the flower- shaped organic and inorganic hybrid structures using the obtained nitrile (4) compound and cyano derivatives.

专利号:US-4006181-A
优先权日:1972-07-27
标 题:Process for the obtaining of esters of acetylsalicylic acid and amino alcohols
发明人：COUSSE HENRI; MOUZIN GILBERT
权利人:FABRE SA PIERRE
摘要:The present invention relates to a new process for the obtaining of dimethylaminoethyl acetylsalicylate and its salts. n It is characterized by the fact that the synthesis of the acid chloride is effected in an aliphatic hydrocarbon in the presence of pyridine as catalyst; after condensation with the dimethylaminoethanol, the product obtained is recovered by crystallization in anhydrous medium. n The products obtained can be used in the pharmaceutical industry.

专利号:US-10927101-B2
优先权日:2016-05-31
标 题 :Neopetrosides A and B, and synthesis method thereof
发明人：HAN JIN; JEONG SEUNG HUN; SONG IN-SUNG; KIM HYOUNG KYU; KIM NARI; SHUBINA LARISA K; MAKARIEVA TATYANA N; STONIK VALENTIN A; YASHUNSKY DMITRY V; NIFANTIEV NIKOLAY E
权利人:UNIV INJE IND ACAD COOP FOUND
摘要:The present invention relates to novel pyridine nucleoside compounds, Neopetroside A (NPS A) and Neopetroside B (NPS B) obtained by fractionating an extract of Neopetrosia sp. which is a marine sponge, with ethanol, into n-butanol (n-BuOH). When the NPS A was treated with myocardial cells, it activates oxidative phosphorylation, basal and mitochondrial respiration induced by ATP and ATP synthesis, and stimulates the glycolysis activity and when the NPS A was treated with an ischemic reperfusion injury model, the left ventricular pressure injured by ischemic reperfusion was recovered and the size of myocardial injury site was significantly reduced and as a result, can be provided as the pharmaceutical composition for preventing or treating ischemic heart disease or the health functional food for preventing or improving the same.

专利号:US-2009285888-A1
优先权日:2005-05-13
标题:Derivatives of dihydroxyphenylalanine
发明人：SUSILO GISELA
权利人:SUSILO GISELA
摘要:The invention relates to derivatives of dihydroxyphenylalanine, to their synthesis and to pharmaceutical compositions containing said derivatives of dihydroxyphenylalanine. Furthermore, the invention relates to the use of said derivatives of dihydroxyphenylalanine and said pharmaceutical compositions for the treatment and prophylaxis of movement disorders, neurodegenerative diseases, Alzheimer's disease, Parkinson's disease, hemiparkinson-hemiatrophy, parkinsonian syndrome, Lewy body disease, frontotemporal dementia, Lytico-Bodig disease (parkinsonism/dementia/amyotrophic lateral sclerosis), striatonigral degeneration, Shy-Drager syndrome, sporadic olivopontocerebellar degeneration, progressive atrophy of the globus pallidus, progressive supranuclear palsy, Hallervorden-Spatz disease, Huntington's disease, X-linked dystonia-parkinsonism (Lubag), mitochondrial cytopathy with striatal necrosis, neuroacanthocytosis, restless legs syndrome, Wilson's disease.

专利号:ES-2239588-T3
优先权日:1999-01-26
标 题 :SYNTHESIS OF ESTERES OF NITROXIMETILFENILO-ESTERES OF ASPIRINA DERIVATIVES.

专利号:CN-1337391-A
优先权日:2001-08-17
标题 :A New Process for the Phosgene Synthesis of a Class of Medicinal Acetylsalicylate Derivatives