CAS: 585-48-8; 2,6-Di-Tert-Butylpyridine

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5944-41-2 38222-83-2 20336-15-6

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CAS号5944-41-2 2-(叔丁基)吡啶 | CAS号85237-75-8 2,6-Di-tert-but... | CAS号2525-19-1 1,2,6-trimethyl... | CAS号74-88-4 碘甲烷 | CAS号935-28-4 2,6-二乙基吡啶 | CAS号62907-61-3 2,6-di-tert-but... | CAS号644-98-4 2-异丙基吡啶 | CAS号108-48-5 2,6-二甲基吡啶 | CAS号109-06-8 2-甲基吡啶 | CAS号6832-21-9 2,6-二-异丙基吡啶 | CAS号92423-50-2 2,6-ditert-buty... | CAS号5944-41-2 2-(叔丁基)吡啶

2-叔丁基吡啶置于乙醚,叔丁基锂,Petroleum Ether体系中,化学反应生成 2,6-二叔丁基吡啶
参考文献:2,6-Di-Butylpyridine-an Unusual Pyridine Base
标题:2,6-Di-Butylpyridine-an Unusual Pyridine Base
摘要:
DOI:10.1021/ja01111A530

专利信息

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-6376649-B1
优先权日:1998-12-18
标题 :Methods for the synthesis of α- hydroxy-β-amino acid and amide derivatives
发明人：SEMPLE JOSEPH E; LEVY ODILE E
权利人:CORVAS INT INC
摘要:Methods for the synthesis of alpha-hydroxy-beta-amino acid and amide derivatives and alpha-ketoamide derivatives and novel derivatives made by these methods are provided. These methods involve reacting a N-terminally blocked (protected) aminoaldehyde with an isonitrile and a carboxylic acid to give an amino-alpha-acyloxy carboxamide. The acyloxy group may be removed to give the derivative. Alternatively the protecting group is removed and acyl shift occurs to give the derivative. These derivatives are useful in the synthesis of compounds such as peptidyl alpha-ketoamides and alpha-hydroxy-beta-carboxylic acid and amide derivatives. Certain of these compounds have been reported to have activity as inhibitors of proteases, such as serine proteases and cysteine proteases.

专利号:US-10919904-B2
优先权日:2016-08-17
标 题 :Northern-southern route to synthesis of bacteriochlorins
发明人：LIU YIZHOU; LINDSEY JONATHAN S; ALLU SRINIVASA RAO; FUJITA HIKARU
权利人:UNIV NORTH CAROLINA STATE
摘要:Described herein are chlorins, bacteriochlorins, methods and intermediates for the synthesis of bacteriochlorins, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as luminescent compounds in flow cytometry, and as active agents in photodynamic therapy (PDT).

专利号:US-8735586-B2
优先权日:2007-06-26
标 题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
发明人：ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR
权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR; SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:US-8642766-B2
优先权日:2008-05-05
标题 :Synthesis of (+) cortistatin A and related compounds
发明人：SHENVI RYAN A; GUERRERO CARLOS A; SHI JUN; LI CHUANG-CHUANG; BARAN PHIL S
权利人:SHENVI RYAN A; GUERRERO CARLOS A; SHI JUN; LI CHUANG-CHUANG; BARAN PHIL S
摘要:An in vitro synthesis of (+) cortistatin A from readily available precursors is disclosed, as are the syntheses of related 17-aryl substituted compounds, the 17-aryl substituted compounds themselves and novel compounds useful in their preparation.

专利号:US-8580975-B2
优先权日:2008-01-11
标 题:Synthesis of macrocyclic cancer chemotherapy agents and methods of use
发明人：GHOSH ARUN K; XU XIAOMING
权利人:GHOSH ARUN K; XU XIAOMING; PURDUE RESEARCH FOUNDATION
摘要:Herein are described a process for forming a quaternary carbon useful in the preparation of macrolactones, an enantioselective synthesis of (+)-peloruside A, and methods for treating a patient in need of relief from cancer or a cancer-related disease. The described processes are useful for preparing compounds containing quaternary carbons, including structural analogs and derivatives of peloruside A.