欧盟法规
C&L通报REACH预注册上下游产品
4-Bromoresorcinol dimethyl sulfate O-methylresorcine 1-Bromo-4-methoxy-2-(methoxymethoxy)benzene 1-Bromo-4-methoxy-2-(methoxymethoxy)benzene 2-(allyloxy)-1-bromo-4-methoxybenzene 2-Acetoxy-1-bromo-4-methoxybenzene 1-bromo-2-isopropoxy-4-methoxybenzene 合成工艺路线路线简述
- 合成目标产物 2-Bromo-5-Methoxyphenol 主要起始原料 Phenol, 2-Bromo-5-Methoxy-, 1-Acetate
- (文献来源)合成步骤主要原料 Phenol, 2-Bromo-5-Methoxy-, 1-Acetate
2,4-二羟基苯甲酸置于水,溶剂黄146体系中,化学反应生成 2-溴-5-甲氧基苯酚
参考文献:Rice,Journal Of The American Chemical Society,1926,Vol. 48,P. 3127
标题:Rice,Journal Of The American Chemical Society,1926,Vol. 48,P. 3127
海关参考信息
- 2905110000-甲醇
2907221000-对苯二酚
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物 - 💡 提示:海关信息按照顺序优先匹配,如需确认的海关信息,请参考相关资料。
- 详情请参考:📖 海关编码查询和海关进出口税则
专利信息
专利号:US-6162932-A
优先权日:1995-11-08
标 题 :Stereoselective synthesis of endothelin receptor antagonists
发明人:MILLS ROBERT JOHN; KOWALSKI CONRAD JOHN; PING LI-JENG; GOMBATZ KERRY JOSEPH
权利人:SMITHKLINE BEECHAM CORP
摘要:The present invention is directed to chiral intermediates in a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A). ##STR1##
专利号:WO-9717071-A1
优先权日:1995-11-08
标 题 :Stereoselective synthesis of endothelin receptor antagonists
发明人:MILLS ROBERT JOHN; KOWALSKI CONRAD JOHN; PING LI-JEN; GOMBATZ KERRY JOSEPH
权利人:SMITHKLINE BEECHAM CORP; MILLS ROBERT JOHN; KOWALSKI CONRAD JOHN; PING LI JEN; GOMBATZ KERRY JOSEPH
摘要:The present invention is directed to a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A) and to the chiral intermediates.
专利号:US-6080862-A
优先权日:1995-11-08
标题 :Stereoselective synthesis of endothelin receptor antagonists
发明人:MILLS ROBERT JOHN; KOWALSKI CONRAD JOHN; PING LI-JENG; GOMBATZ KERRY JOSEPH
权利人:SMITHKLINE BEECHAM CORP
摘要:PCT No. PCT/US96/18084 Sec. 371 Date May 8, 1998 Sec. 102(e) Date May 8, 1998 PCT Filed Nov. 8, 1996 PCT Pub. No. WO97/17071 PCT Pub. Date May 15, 1997The present invention is directed to a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A) and to the chiral intermediates
专利号:US-2024335442-A1
优先权日:2021-08-02
标 题:N-acylhydrazone compounds capable of inhibiting nav1.7 and/or nav1.8, processes for the preparation thereof, compositions, uses, methods for treatment using same, and kits
发明人:BARREIRO GABRIELA; SANT'ANA DANILO PEREIRA DE; GAMBA LUIS EDUARDO REINA; FRAGA CARLOS ALBERTO MANSSOUR; BARREIRO ELIEZER JESUS DE LACERDA; LIMA LÃ?DIA MOREIRA
权利人:EUROFARMA LABORATORIOS S A; UNIV FEDERAL DO RIO DE JANEIRO UFRJ
摘要:N-acylhydrazone compounds that are Nav 1.7 and/or Nav 1.8 inhibitors, including N-acylhydrazone compounds of Formula (I), wherein the substituents R1 to R6 are independently selected from the groups defined in the specification, as well as to the processes for the preparation thereof, compositions comprising at least one of said compounds, uses, treatment methods for treating or preventing pain-related pathologies, and kits, and which are applicable in the fields of medicinal chemistry and organic synthesis, as well as in the treatment of pain-related disorders.
专利号:JP-2000507918-A
优先权日:1995-11-08
标 题:Stereoselective synthesis of endothelin receptor antagonists
专利号:EP-0915699-A1
优先权日:1995-11-08
标 题 :Stereoselective synthesis of endothelin receptor antagonists