CAS: 64248-58-4; 1,2-Difluoro-4-Iodobenzene

上下游产品

CAS号348-61-8 3,4-二氟溴苯 | CAS号68290-36-8 2-(3,4-二氟苯基)吲哚 | CAS号333780-75-9 2,3-二氟-6-碘苯甲酸

3,4-二氟溴苯置于碘,Magnesium体系中,用 四氢呋喃 作为反应溶剂,化学反应生成 1,2-二氟-4-碘代苯
参考文献:Synthesis And Mesomorphic Properties Of Some Liquid Crystals With 2,3,5,6-Tetrafluorophenylene Unit
标题:Synthesis And Mesomorphic Properties Of Some Liquid Crystals With 2,3,5,6-Tetrafluorophenylene Unit
摘要:Nine Fluorosubstituted Liquid Crystals Have Been Synthesized And Their Mesomorphic Properties Have Been Studied By Texture Observation In A Polarizing Microscope And Confirmed By Dsc. They Show Enantiotropic Smectic A And Nematic Phases. The Effect Of Terminal And Lateral Fluorosubstitution Is Also Discussed.
DOI:10.1080/10587250210542

专利信息

专利号:WO-2018109082-A1
优先权日:2016-12-15
标题 :Process and intermediate for the preparation of 1-(4-(2-((1-(3,4- difluorophenyl)-1h-pyrazol-3-yl)methoxy)ethyl)piperazin-1-yl)ethanone
发明人：ALMANSA ROSALES CARMEN; CAAMAÑO MOURE ANA MARÃ?A; ENJO BABÃ?O JUAN
权利人:ESTEVE LABOR DR
摘要:The present invention relates to a process for the preparation of 1-(4-(2-((1-(3,4-difluorophenyl)-1H-pyrazol-3-yl)methoxy)ethyl)piperazin-1-yl)ethanone and salts and solvates thereof and to the use of intermediates in the synthesis of these compounds. Also is provided a new intermediate compound.

专利号:WO-0009116-A1
优先权日:1998-08-14
标 题:Grp receptor ligands
发明人：XIANG JIA-NING; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
权利人:SMITHKLINE BEECHAM CORP; XIANG JIA NING; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
摘要:Novel GRP receptor antagonists are provided. Methods of using the present compounds to antagonize GRP receptors are also provided. The present invention further involves the synthesis of the present compounds.

专利号:WO-0009115-A1
优先权日:1998-08-14
标 题 :Grp receptor ligands
发明人：XIANG JIA-NING; OSIFO IRENNEGBE KELLY; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
权利人:SMITHKLINE BEECHAM CORP; XIANG JIA NING; OSIFO IRENNEGBE KELLY; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
摘要:Novel GRP receptor antagonists are provided. Methods of using the present compounds to antagonize GRP receptors are also provided. The present invention further involves the synthesis of the present compounds.

专利号:EP-3210987-A1
优先权日:2007-08-06
标 题:Process for the synthesis of proteasome inhibitors