专利号:EP-4342918-A1 优先权日:2022-09-21 标 题:Process for the synthesis of sterically crowded and synthetically challenging alkyl alkoxy silanes using organolithium reagents 发明人:SENTHIL KUMAR MINOR; PAGHABAR BHARATKUMAR RAVJI 权利人:SABIC GLOBAL TECHNOLOGIES BV 摘要:A process for the preparation of mono- or di- alkyl alkoxy silanes according to Formula 3 or Formula 5, said process comprising the following step i) contacting an alkoxy silane according to formula 2 with an organolithium reagents according to Formula 1 to form a mono- or di- alkyl alkoxy silanes according to formula 3 and lithium compound according to formula 4
专利号:US-7309799-B2 优先权日:2004-06-01 标 题:Methods for the synthesis of milnacipran and congeners thereof 发明人:BUCHWALD STEPHEN L; SWAGER TIMOTHY M; RARIY ROMAN V 权利人:COLLEGIUM PHARMACEUTICAL INC 摘要:One aspect of the present invention relates to methods for synthesizing milnacipran or congeners thereof. Another aspect of the present invention relates to asymmetric methods for synthesizing enantiomerically enriched milnacipran or congeners thereof. The present invention also relates to methods for synthesizing intermediates useful in the non-asymmetric or asymmetric methods for synthesizing enantiomerically enriched milnacipran or congeners thereof.
专利号:US-2003072716-A1 优先权日:2001-06-22 标 题:Renewable, carbohydrate based CO2-philes 发明人:POOVATHINTHODIYIL RAVEENDRAN; WALLEN SCOTT L 摘要:A composition is disclosed comprising a carbohydrate-based material a dispersed in carbon dioxide. A general method for synthesizing inexpensive, renewable, non-toxic, non-fluorous, carbohydrate based CO 2 -philes is disclosed. These CO 2 -philes are soluble in carbon dioxide. Methods of making the composition are also disclosed. The methods and composition are useful in a variety of applications and can utilize gaseous, liquid and supercritical carbon dioxide. The methods and compositions are useful in the synthesis of surfactants and metal chelates for CO 2 , as a sizing substrate, in CO 2 -based coating processes, for impregnation and plasticizing cellulosic and non-cellulosic materials, in pharmaceutical applications, such as crystallization, dispersion and encapsulation of bioactive molecules in solid systems, in the densification of CO 2 , in the synthesis of biodegradable polymers in CO 2 , and for carbon dioxide removal, to name just a few.
专利号:US-2022355262-A1 优先权日:2019-07-22 标题 :System and method for manufacturing water-based hydrophobic aerogels and aerogel composites 发明人:SACHITHANADAM MAHESH; KHORASGANI SOGHRATI ELMIRA; NATARAJAN GAYATHRI 权利人:KROSSLINKER PTE LTD 摘要:Embodiments of the present invention provide users with a system and method for manufacturing water-based hydrophobic aerogels and aerogel composites. The system and method can be carried out in a manner which is more rapid than typical ways and can be readily scalable. The method of manufacture is useful for producing water based hydrophobic aerogels and aerogel composites on a large scale with good homogeneity and consistency. Advantageously, the method of manufacture also has the benefit of a shorter processing time due to the vacuum homogenizing and mixing processes, the use of microwave assisted vacuum freeze drying for ease of synthesis of water-based hydrophobic aerogels.
专利号:US-6177534-B1 优先权日:1997-12-23 标题 :Silylated resins and the synthesis thereof 发明人:ANTONUCCI JOSEPH M; STANSBURY JEFFREY W; FOWLER BRUCE O 权利人:US COMMERCE 摘要:A silylated resin suitable for use as an adhesive binder for composites and in sealant and adhesive dental applications is represented by the general formula (I): n in which: n R 1 is an aliphatic, cycloaliphatic, aryl, hydrocarbon, or fluorocarbon group; n R 2 is the same as R 1 or a different aliphatic, cycloaliphatic, aryl, hydrocarbon, or fluorocarbon group; n M 2 is the same as M 1 or a different functional or nonfunctional group selected from the group consisting of: n n is 1-3; n x is 1-20; and n y is 1-20; n which comprises the reaction product of the exchange reaction of a hydroxylated, aminated, or carboxylated acrylic resin represented by the general formula (II): n in which: n R 4 is an aliphatic, cycloaliphatic, aryl, hydrocarbon, or fluorocarbon group with one or more protic functional groups selected from the group consisting of: n n n OH, N—H, and CO 2 H n n n R 5 is H or CH 3 ; and n R 6 is H or CH 3 ; n with a trialkoxyorganosilane or triacyloxyorganosilane represented by the general formula (III): n in which: n R 7 , R 8 , and R 9 each is: n R 10 is an aliphatic, or aryl group which can optionally be substituted with a group from the group of an acrylic group, a methacrylic group, an epoxy group, and a substituted amino, hydroxyl, or carboxylic acid group such as an ester or an amide.
专利号:US-9896523-B2 优先权日:2015-06-26 标题 :Ziegler-Natta catalyst synthesis and process thereof 发明人:SINGH GURMEET; KUMAR NARESH; KAUR SUKHDEEP; BANTU BHASKER; KAPUR GURPREET SINGH; SHASHIKANT 权利人:INDIAN OIL CORP LTD 摘要:The present invention describes a process of preparing a catalyst for olefin polymerization comprising: (i) treating a magnesium metal with an organohalide along with an internal donor to obtain a reaction mixture having solid component (A); (ii) treating the reaction mixture having solid component (A) with an acyl halide to obtain a reaction mixture having solid component (B); and (iii) treating the reaction mixture having solid component (B) of step (ii) with a transition metal compound to obtain the catalyst. The present invention also relates to a process for preparation of a catalyst system from said catalyst and preparation of a polyolefins from the catalyst system.
参考标题:Synthesis Of Aliphatic Amides Through A Photoredox Catalyzed Radical Carbonylation Involving Organosilicates As Alkyl Radical Precursors 作者:Alex Cartier,Etienne Levernier,Anne‐lise Dhimane,Takahide Fukuyama,Cyril Ollivier,Ilhyong Ryu,Louis Fensterbank |发布日期:2020.5.26 摘要:Alkyl Radicals, From Primary To Tertiary, Formed By Photocatalyzed Oxidation Of Organosilicates, Are Involved Efficiently In Radical Carbonylation With Carbon Monoxide (Co), In The Presence Of Various Amines And Ccl4, Leading To A Variety Of Amides In Moderate To Good Yields.
合成参考文献
摘要:Corcé, V.; Lévêque, C.; Ollivier, C.; Fensterbank, L., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 428. 摘要:Corcé, V.; Lévêque, C.; Ollivier, C.; Fensterbank, L., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 433.