专利号:US-6093415-A 优先权日:1997-02-12 标题:Synergistic juvenoid chitin synthesis inhibitor termiticide compositions 发明人:KARR LAURA L; SBRAGIA RONALD J 权利人:DOW AGROSCIENCES LLC 摘要:Combinations of a chitin synthesis inhibitor (e.g. hexaflumuron, flufenoxuron, lufenuron, and dimiin) with a juvenile hormone mimic (e.g. methoprene and pyriproxyfen) afford synergistic activity against termites.
专利号:RU-2035447-C1 优先权日:1992-06-30 标 题:Method of synthesis of 2,6-difluoro-n-alkylbenzenes
专利号:US-5354905-A 优先权日:1992-10-23 标 题 :N-alkoxymethyl benzamide derivative and manufacturing method therefor, and manufacturing method for benzamide derivative using this N-alkoxymethyl benzamide derivative 发明人:SATO YOSHIHIRO; KOISO AKIHIRO; ASADA TOHRU; MIURA YASUHISA; KIKUCHI YASUO; HARIYA YASUAKI 权利人:YASHIMA KAGAKU KOGYO KK 摘要:An N-alkoxymethyl benzamide derivative represented by Formula (I); (I) (In the formula, reference X indicates a halogen atom, references Y1 and Y2 indicate hydrogen atoms or halogen atoms, and may be identical or different, and reference R indicates a lower alkyl group.) and a manufacturing method for this N-alkoxymethyl benzamide derivative in which a substituted benzamide and an alpha -haloacetal are reacted. Furthermore, a manufacturing method for benzamide derivatives in which the N-alkoxymethyl benzamide derivative represented by Formula (I) above and benzene or a derivative thereof are reacted, and a benzamide derivative is produced. The N-alkoxymethyl benzamide derivative of the present invention is a novel compound, and possesses utility as an intermediate in the manufacturing of oxazoline derivatives which possess insecticidal and anti-mite activity, and as a starting material for the synthesis of various organic compounds and the like.
专利号:US-7169932-B2 优先权日:2001-06-11 标题:HIV protease inhibitors, compositions containing the same, their pharmaceutical uses, material for their synthesis 发明人:KUCERA DAVID JOHN; SCOTT ROBERT WILLIAM 权利人:PFIZER 摘要:Compounds of the formula: n nwhere the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.
专利号:US-5096710-A 优先权日:1989-05-27 标 题 :Poison bait for control of noxious insects 发明人:MINAGAWA FUMIYASU; KOHAMA TAKUJI; KAWADA HITOSHI; SHINJO GORO; MAEDA KAZUYUKI 权利人:SUMITOMO CHEMICAL CO 摘要:A bait composition in a tablet form, which comprises as the essential components (a) at least one insect-growth controlling agent chosen from (a-1) insect juvenile hormone-like compounds and (a-2) insect chitin-synthesis inhibitors, (b) dextrin and (c) a plant oil in an amount of not more than 10% by weight to the total bait composition.
专利号:US-7122549-B2 优先权日:2000-11-03 标题:Saframycins, analogues and uses thereof 发明人:MYERS ANDREW G; PLOWRIGHT ALLEYN T 权利人:HARVARD COLLEGE 摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel compounds of general formula (I), and methods for the synthesis thereof. n n n n n n n n n n In another aspect, the present invention provides pharmaceutical compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier. In yet another aspect, the present invention provides methods for treating cancer comprising administering a therapeutically effective amount of a compound of formula (I) to a subject in need thereof.
[参考文献]: J Koerts, Et Al. Metabolism Of The Insecticide Teflubenzuron In Rats. Xenobiotica. 1997 Aug;27(8):801-17. [参考文献]: Varahenage R Perera, Et Al. Purification And Characterization Of The Staphylococcus Aureus Bacillithiol Transferase Bsta. Biochim Biophys Acta. 2014 Sep;1840(9):2851-61.
合成参考文献
摘要:Asano, Y., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 258. 参考文献:10.1107/s1600536810035725 摘要:Pourayoubi M, Tarahhomi A, Rheingold AL, Golen JA. N,N′-Dibenzyl-N′′-(2,6-difluorobenzoyl)-N,N′-dimethylphosphoric triamide. Acta Crystallogr E Struct Rep Online. 2010 Sep 11;66(10):o2524. doi: 10.1107/s1600536810035725. 参考文献:10.1107/s1600536810045927 摘要:Pourayoubi M, Tarahhomi A, Rheingold AL, Golen JA. N,N′-Di-tert-butyl-N′′-(2,6-difluorobenzoyl)phosphoric triamide. Acta Crystallogr E Struct Rep Online. 2010 Nov 13;66(12):o3159. doi: 10.1107/s1600536810045927.