CAS: 18638-99-8; (3,4,5-Trimethoxyphenyl)Methanamine

该化合物是一种多用途芳香剂,其特征是三甲基苯基替代苯基核心;该化合物因其电子富含芳香系统,在有机合成和制药研究中具有价值,因为其具有高电子芳香系统,在电子代用和凝聚反应中增强了反应性;甲氧基组有助于消毒和电子调制,使其成为生产生物活性分子,包括藻类和CNS活性化合物的有用中间体;在标准条件下保持稳定,与一系列试剂的兼容性进一步突出了其在多步合成中的效用;该化合物通常在惰性条件下处理,以保持其地雷的功能;在高纯度情况下,它适合于实验室规模和工业用途.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号39201-89-3 3,4,5-三甲氧基苄肟 | CAS号1885-35-4 3,4,5-三甲氧基苯甲腈 | CAS号3086-62-2 3,4,5-三甲氧基苯甲酰胺 | CAS号55100-33-9 3,4,5-trimethox... | CAS号64-17-5 乙醇 | CAS号1885-35-4 3,4,5-三甲氧基苯甲腈 | CAS号94271-52-0 苄基-(3,4,5-三甲氧基苄基)胺

合成工艺路线路线简述

    3,4,5-三甲氧基苯甲酰胺置于16Eu(3+)*20C5H4F3O2(1-)*8Ch4O*24Ho(1-)*2O(2-),频那醇硼烷体系中,用 甲苯 用作溶剂,以92 %的收率获得3,4,5-三甲氧基苄胺
    参考文献:用于高效催化还原甲酰胺的镧系氧簇
    标题:用于高效催化还原甲酰胺的镧系氧簇
    摘要:将甲酰胺还原成高附加值的胺是一个非常有趣但极具挑战性的课题.在本文中,我们证明多核镧系元素-氧簇 Ln 16(ln = Eu 和 Gd)可用作高效催化剂,将伯甲酰胺和仲甲酰胺还原为胺,产率为 71%-98%,底物范围广.该方法可以扩展到苯乙胺药物的克级合成,收率为 93%.基于催化中间体的分离和表征,提出了涉及多路径反应的催化机理.这项工作为将甲酰胺还原为胺提供了有效的镧系元素簇催化剂.
    Doi:10.1007/s11426-022-1493-Y

    海关参考信息

    专利信息


    专利号:WO-2021260722-A1
    优先权日:2020-06-21
    标 题:Design, synthesis of novel oxyindole inhibitors of denv rna dependent rna polymerase
    发明人:GUNDLA RAMBABU; ASTHANA SHAILENDRA; BHATTACHARYYA SANKAR; MADDIPATI VENKATANARAYANA CHOWDARY; MITTAL LOVIKA; KAUR JASKARAN; RAWAT YOGITA
    权利人:TRANSLATIONAL HEALTH SCIENCE AND TECH INSTITUTE; GANDHI INSTITUTE OF TECH AND MANAGEMENT
    摘要:The present invention is drawn to novel compounds of formula I, II and III, including any conformational isomeric form, salts and solvates for inhibition of DENV RNA dependent and RNA polymerase. The present invention also discloses a process of synthesis of the compounds, compositions comprising the said compounds and use of the compounds and treatment comprising the compounds of the present invention.

    专利号:US-10188136-B2
    优先权日:2016-02-16
    标题:Hydrophobin mimics: process for preparation thereof
    发明人:BRITTO Sandanaraj Selvaraj; REDDY Mullapudi Mohan; BHANDARI PAVANKUMAR JANARDHAN; RAO KASULADEVU JAGANNADHA
    权利人:INDIAN INSTITUTE OF SCIENCE EDUCATION AND RES
    摘要:The present invention discloses hydrophobin mimics of formula (I) comprising a protein head group, hydrophilic linker and hydrophobic tail and to a process for synthesis of library of hydrophobin mimics thereof. The hydrophobin mimics of the present invention self-assemble to form protein nanoparticles/nanocontainer either alone or in a specified chemical environment. The hydrophobin mimics (I) of the present invention find application in area of bio-nanotechnology.

    专利号:US-6187923-B1
    优先权日:1998-11-09
    标题 :Process for the synthesis of quinazolinones
    发明人:DENER JEFFREY MARK; LY CUONG QUOC
    权利人:AXYS ADVANCED TECHNOLOGIES INC
    摘要:The present invention provides a process for synthesizing a compound or a library of compounds of Formula 1A and 1B:

    专利号:US-8273403-B2
    优先权日:2002-05-10
    标题 :Generation of surface coating diversity
    发明人:BARDEN MICHAEL C; KAMBOURIS PETER A
    权利人:BARDEN MICHAEL C; KAMBOURIS PETER A; BIO LAYER PTY LTD
    摘要:This invention relates to a surface discovery system and high-throughput combinatorial synthesis methods for generating large numbers of diverse surface coatings on solid substrates. The system is built upon a synthon which comprises at least three elements: a chemical backbone coating on the solid substrate that comprises a copolymer (B) of at least one passive constituent (P) and at least one active constituent (A); a spacer unit (S) separating the backbone from a functional group; and a functional group (F). The methods comprise the following steps: 1) selecting a plurality of synthons so that each synthon has at least two points of diversity selected from P, A, S and F; 2) applying copolymer B onto a substrate; and 3) attaching a combination of S and F to constituent A of copolymer B. Steps 2) and 3) are performed such that different synthons are generated on localized regions of the substrate.

    专利号:US-4288453-A
    优先权日:1977-10-07
    标 题 :Derivatives of arylalkanoic acids, compositions and use
    发明人:VINCENT MICHEL; DUHAULT JACQUES; BOULLANGER MICHELLE; REMOND GEORGES
    权利人:SCIENCE UNION & CIE
    摘要:There are now described some novel alpha-[1-aryl-2,2,2-trifluoroethoxy (or-ethylthio)]alkanoic acids that are useful for reducing triglycerides and cholesterol levels in the blood of animals. The percentage reduction in test rats has been observed to be from 20 to 65 for triglycerides and from 15 to 50 for cholesterol. A representative compound of the invention is alpha-(2,2,2-trifluoro-1-phenyl-1-ethoxy)butyric acid. Most of the compounds have an LD 50 greater than 800 mg/kg, intraperitoneally, in male mice. n A method of use, compositions, and a process for synthesis are also described.

    专利号:US-10458995-B2
    优先权日:2016-03-25
    标 题 :Combinatorial synthesis and biomarker development
    发明人:MOOLA MURALIDHAR REDDY
    权利人:MOOLA MURALIDHAR REDDY
    摘要:Provided herein are methods, kits, and compositions for use in the diagnosis and treatment of diseases. Peptoids recognized by Alzheimers disease specific antibodies are identified.
    台州市创源工业技术有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.tzchemical.com
    企业联系电话:13757609826;0576-85289468👤
    📞台州市创源工业技术有限公司 ⚠️参考联系方式
    联系人:徐经理
    电话:13757609826;0576-85289468
    手机:13757609826
    传真:0576-85289468
    邮箱:sales@tzchemical.com
    通信地址: 浙江省临海市清化路7号大洋基地一区十七幢
    邮编: 317000
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:浙江省临海市清化路7号大洋基地一区十七幢
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    上海威远精细氟科技发展有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.shwychem.com
    企业联系电话:021-64251386 64253204👤
    📞上海威远精细氟科技发展有限公司 ⚠️参考联系方式

    电话:021-64251386 64253204

    传真:021-64253354
    邮箱:wdchen@shwychem.com
    通信地址: 上海梅陇路130号华东理工科技大楼
    邮编: 200237
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:上海梅陇路130号华东理工科技大楼
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    上海氟德化工有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.fwdchem.com.cn
    企业联系电话:021-54450828,13501997194👤
    📞上海氟德化工有限公司 ⚠️参考联系方式
    联系人:周先生
    电话:021-54450828,13501997194
    手机:13501997194
    传真:021-54450901
    邮箱:sales@fwdchem.com
    通信地址: 上海市徐汇区田州路159号15单元莲花大厦802室
    邮编: 200233
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:上海市徐汇区田州路159号15单元莲花大厦802室
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    第 1 / 1 页
    现货

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Facile Synthesis Of Controllable Graphene-Co-Shelled Reusable Ni/nio Nanoparticles And Their Application In The Synthesis Of Amines Under Mild Conditions
    作者:Jianguo Liu,Yuting Zhu,Chenguang Wang,Thishana Singh,Nan Wang,Qiying Liu,Zhibing Cui,Longlong Ma
    摘要:Catalysts Are Stable And Reusable And Were Successfully Used For The Synthesis Of Primary, Secondary, Tertiary, And N-Methylamines (More Than 62 Examples). The Reaction Couples Easily Accessible Carbonyl Compounds (Aldehydes And Ketones) With Ammonia, Amines, And H2 Under Very Mild Industrially Viable And Scalable Conditions (80 °C And 1 Mpa H2 Pressure, 4 H), Offering Cost-Effective Access To Numerous Functionalized

    合成参考文献


    参考文献:10.1126/sciadv.abf8711
    摘要:Schuller M, Correy GJ, Gahbauer S, Fearon D, Wu T, Díaz RE, Young ID, Carvalho Martins L, Smith DH, Schulze-Gahmen U, Owens TW, Deshpande I, Merz GE, Thwin AC, Biel JT, Peters JK, Moritz M, Herrera N, Kratochvil HT; QCRG Structural Biology Consortium, Aimon A, Bennett JM, Brandao Neto J, Cohen AE, Dias A, Douangamath A, Dunnett L, Fedorov O, Ferla MP, Fuchs MR, Gorrie-Stone TJ, Holton JM, Johnson MG, Krojer T, Meigs G, Powell AJ, Rack JGM, Rangel VL, Russi S, Skyner RE, Smith CA, Soares AS, Wierman JL, Zhu K, O'Brien P, Jura N, Ashworth A, Irwin JJ, Thompson MC, Gestwicki JE, von Delft F, Shoichet BK, Fraser JS, Ahel I. Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Sci Adv. 2021 Apr;7(16).
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知