专利号:US-11692058-B2 优先权日:2021-02-26 标题:Synthesis of functional polyurethanes and polyesters from biomass-derived monomers 发明人:CHANG HOCHAN; HUBER GEORGE W; DUMESIC JAMES A 权利人:WISCONSIN ALUMNI RES FOUND 摘要:A method of making polyesters and polyurethanes from biomass-derived polyols. The polyol is biomass-derived and has the structure:wherein dashed bonds are single or double bonds and R is selected from the group consisting of —OH and â•?O. Polyurethanes are made by reacting the polyol with a diisocyanate. Polyesters are made by reacting the polyol with a dicarboxylic acid.
专利号:US-2024239791-A1 优先权日:2021-04-26 标题 :Processes for the synthesis of valbenazine 发明人:TUCKER JOHN LLOYD 权利人:NEUROCRINE BIOSCIENCES INC 摘要:The present application relates to processes for preparing (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate), which is an inhibitor of vesicular monoamine transporter 2 (VMAT2) useful in the treatment of hyperkinetic movement disorders such as tardive dyskinesia (TD).
专利号:US-2022288005-A1 优先权日:2019-07-26 标题:Synthesis of pro-resolving analogs and compositions therefor 发明人:VAN DYKE THOMAS E; SERHAN CHARLES N 权利人:NOCENDRA INC 摘要:This disclosure relates to methods of synthesizing certain lipoxin analogs (e.g., lipoxin mimetics, etc.) and pharmaceutical compositions comprising these pro-resolving compounds. Methods of administering the lipoxin mimetics (e.g., lipoxin A4 mimetics, lipoxin B4 mimetics, etc.) to patients in need thereof are also provided.
专利号:US-2022363680-A1 优先权日:2019-09-13 标题 :Processes for the synthesis of valbenazine 发明人:TUCKER JOHN; KUCERA DAVID; HETTINGER DONALD; COCHRAN BRIAN M; BRANUM SHAWN; LE JACKIE; MCGEE KEVIN 权利人:NEUROCRINE BIOSCIENCES INC 摘要:The present application relates to processes for making (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b -hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl (S)-2-amino-3-methylbutanoate di(4-methylbenzenesulfonate), which is an inhibitor of vesicular monoamine transporter 2 (VMAT2) useful in the treatment of hyperkinetic movement disorders such as tardive dyskinesia (TD).
专利号:US-11559556-B2 优先权日:2019-03-15 标题:Citrus fruit extract-mediated synthesis of tellurium nanomaterials having biomedical applications 发明人:MEDINA CRUZ DAVID; TIEN-STREET WILLIAM; ZHANG BOHAN; HUANG XINJING; CRUA ADA VERNET; WEBSTER THOMAS J 权利人:UNIV NORTHEASTERN 摘要:Methods disclosed herein provide for an environmentally-friendly approach that employ citric extracts from fruits as unique reducing and stabilizing agents for making a tellurium nanomaterial. A particular method of making a tellurium nanomaterial includes combining citrus fruit extract with a tellurium salt to form a mixture of citrus fruit extract and dissolved tellurium salt; and heating the mixture of citrus fruit extract and dissolved tellurium salt, thereby making the tellurium nanomaterial. The resulting nanoparticles exhibit enhanced and desirable biomedical properties toward treatment of both infectious diseases and cancer.
专利号:US-12110347-B2 优先权日:2014-05-29 标 题:Enzymatic synthesis of soluble glucan fiber 发明人:CHENG QIONG; DICOSIMO ROBERT; OUWEHAND ARTHUR; YOU ZHENG; PAYNE MARK S; LAI JIAN PING; RUEBLING-JASS KRISTIN; ROTHMAN STEVEN CARY 权利人:NUTRITION & BIOSCIENCES USA 4 INC 摘要:An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.
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合成参考文献
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