CAS: 75178-96-0; Tert-Butyl (3-Aminopropyl)Carbamate

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CAS号24424-99-5 二碳酸二叔丁酯 | CAS号109-76-2 1,3-丙二胺 | CAS号53588-95-7 (2-氰基乙基)氨基甲酸叔丁酯 | CAS号129392-84-3 N-B°C-3-叠氮基-丙胺 | CAS号762-75-4 甲酸叔丁酯 | CAS号6627-89-0 叔丁基苯基碳酸酯 | CAS号13319-71-6 6-溴邻甲酚 | CAS号34619-03-9 碳酸二叔丁酯 | CAS号258332-57-9 N-[3-(叔丁氧羰氨基)丙基... | CAS号53588-95-7 (2-氰基乙基)氨基甲酸叔丁酯 | CAS号82409-04-9 b°C-3,3'-iminod... | CAS号85503-20-4 N1,N4-双-B°C-亚精胺 | CAS号52054-87-2 methyl N-pyridi... | CAS号386281-18-1 t-Butyl 3-{[(4-...

1-N-Tert-Butoxycarbonyl-3-N-(3-Methyl-2-Butenyl)Oxycarbonyl-1,3-Diaminopropane置于碘,锌体系中,用 甲醇 作为反应溶剂,化学反应 7.5H,以82%的收率获得产物n-叔丁氧羰基-1,3-丙二胺
参考文献:One-Pot Selective Cleavage Of Prenyl Carbamates Using Iodine In Methanol Followed By Zinc
标题:One-Pot Selective Cleavage Of Prenyl Carbamates Using Iodine In Methanol Followed By Zinc
摘要:The Prenyloxycarbonyl (Preoc) Moiety Was Efficiently Removed From Carbamates To Provide The Corresponding Amines In Good To Excellent Yields (63-88%) By Using Iodine In Methanol Followed By Treatment Of The Resulting Beta-Methoxyiodides By Zinc Powder. The Reaction Conditions Are Compatible With The Presence Of A Number Of Functional Groups Such As Boc And Cbz Carbamates,Sulfides,Double Bonds,Indoles And Aromatic Methyl Ethers. (C) 2003 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tetlet.2003.10.058

专利信息

专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人：HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

专利号:US-6410643-B1
优先权日:2000-03-09
标题 :Solid phase synthesis method and reagent
发明人：SWANSON MELVIN J
权利人:SURMODICS INC
摘要:A reagent composition adapted to be coated onto a support surface in order to provide that surface with a high density of reactive groups. The surface, thus coated, can be used for any suitable purpose, and is particularly well suited for use as a solid phase synthesis support surface. The synthesis support surface, in turn, can be used in repetitive and combinatorial syntheses such as the synthesis of polynucleotides, polypeptides and polysaccharides. The polymeric coating can be used to provide increased effective surface area, particularly in situations in which the effective area of the support surface is itself limited, as on the surface of a silicon wafer. In so doing, the polymeric coating provides an optimal combination of such properties as reactive density and surface area or volume.

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-2024051897-A1
优先权日:2022-07-26
标题:Synthesis of complex 15n-labeled molecules
发明人：DORSHEIMER JULIA; ROVIS TOMISLAV
权利人:UNIV COLUMBIA
摘要:Methods for conversion of a broad range of amines to their 15N isotopic counterparts and the compounds produced thereby.

专利号:RU-2205834-C2
优先权日:1997-08-01
标题 :Method of synthesis of [2-((8,9)-dioxo-2,6-diazobi-cyclo-[5,2,0]non-1(7)-en-2-yl)ethyl]phosphonic acid, method of synthesis of n-[3-(tertiary butyloxy- carbonylamino)propyl]-2-aminoethylphosphonic acid di-c1-c6-alkyl ester, compounds

专利号:WO-2009140467-A1
优先权日:2008-05-15
标 题:Oxobenzindolizinoquinolines and uses thereof
发明人：CUSHMAN MARK S; CINELLI MARIS A; MORRELL ANDREW E; POMMIER YVES G
权利人:PURDUE RESEARCH FOUNDATION; CUSHMAN MARK S; US GOV HEALTH & HUMAN SERV; CINELLI MARIS A; MORRELL ANDREW E; POMMIER YVES G
摘要:The synthesis of aromathecins, substituted 12 H -5,l la-diazadibenzo[ b,h ]fluoren- 11 -ones is described. Use of these cytotoxic compounds and pharmaceutical compositions containing them for the treatment of cancer is described. Two novel processes for the synthesis of this system and a series of 14-substituted aromathecins as novel cytotoxic, topoisomerase I poisons are described.