CAS: 85-19-8; (5-Chloro-2-Hydroxyphenyl)(Phenyl)Methanone

该化合物是一种有机化合物,通常用于各种化妆品和个人护理产品中的紫外线过滤器,其特点是能够吸收紫外线光,保护皮肤和头发免受紫外线辐射损害;该化合物的特点是苯并苯并芬内结构,由两个由碳基集团连接的芳香环组成,并增加了氢氧基和甲基氧基的替代成分,以提高其溶解度和配方的功效.苯并苯并芬-7通常是白色至黄色固体,在有机溶剂中溶解,但在水中溶解度有限.紫外线下的稳定性使其在防晒太阳,润滑剂和其他旨在防晒太阳的产品中成为受欢迎的选择.然而,与许多紫外线过滤器一样,它引起了对潜在的皮肤刺激和环境影响的关切,促使人们不断研究其安全和管制状况.总的来说,苯同在化妆品工业中,在摄影保护方面起着重要作用.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号635-93-8 5-氯水杨醛 | CAS号71-43-2 苯 | CAS号2005-08-5 苯甲酸4-氯苯酯 | CAS号1483-73-4 二苯基溴化碘鎓 | CAS号591-50-4 碘苯 | CAS号98-88-4 苯甲酰氯 | CAS号106-48-9 对氯苯酚 | CAS号26965-67-3 4-chloro-2-(hyd... | CAS号108-86-1 溴苯 | CAS号14098-31-8 6-chloro-4-phen... | CAS号26965-47-9 5-氯-3-苯基-1-苯并呋喃-2-羧酸 | CAS号26965-48-0 5-Chloro-3-phen... | CAS号657-84-1 对甲苯磺酸钠 | CAS号120-32-1 4-氯-2-苄基苯酚 | CAS号117-99-7 2-羟基二苯甲酮 | CAS号16611-67-9 2,5-二氯二苯甲酮 | CAS号69149-42-4 [2-(2-aminoetho... | CAS号89718-92-3 2-[4-chloro-2-(... | CAS号89718-93-4 2-[4-chloro-2-(...

合成工艺路线路线简述

  • 98-80-6 + 635-93-8 = 85-19-8
    反应条件:1.1 Reagents: Cupric Acetate Catalysts: Bis[dichloro[η5-(Pentamethylcyclopentadienyl)]Rhodium] Solvents: Dimethylformamide; 8 H,80 °C
    标题:Rh(Iii)-Catalyzed Aldehyde C-H Bond Functionalization Of Salicylaldehydes With Arylboronic Acids
    作者:Wang,Dahai; Cui,Sunliang
    参考文献:Tetrahedron 日期:2015 卷标:71(45) 页码:8511-8516]

    2005-08-5 = 85-19-8
    反应条件:1.1 Reagents: Sodium Dodecyl Sulfate Catalysts: Hexadecyltrimethylammonium Chloride,Polyethylene Glycol Lauryl Ether Solvents: Water; 1 H,25 °C
    标题:Substituent And Surfactant Effects On The Photochemical Reaction Of Some Aryl Benzoates In Micellar Green Environment
    作者:Siano,Gaston; Crespi,Stefano; Bonesi,Sergio M.
    参考文献:Photochemistry And Photobiology 日期:2021 卷标:97(6) 页码:1298-1309]

    98-88-4 = 85-19-8
    反应条件:1.1 Catalysts: Aluminum Chloride; 10 Min,110 °C1.2 Reagents: Water; Cooled
    标题:Chemoselective C-Benzoylation Of Phenols By Using Alcl3 Under Solvent-Free Conditions
    作者:Gaikwad,Sunil V.; Nawghare,Beena R.; Lokhande,Pradeep D.
    参考文献:Bulletin Of The Chemical Society Of Ethiopia 日期:2015 卷标:29(2) 页码:319-325]

    2005-08-5 = 85-19-8
    反应条件:1.1 Reagents: Aluminum Chloride; 6 H,110 °C
    标题:Efficient Synthetic Method Of 1,2-Substituted Benzimidazoles
    作者:Zhao,Hui; Xia,Ya-Mu; Jian,Pan-Ming
    参考文献:Zhongguo Xiandai Yingyong Yaoxue 日期:2008 卷标:25(3) 页码:209-210]

    98-88-4 = 85-19-8
    反应条件:1.1 Catalysts: Trifluoromethanesulfonic Acid; 0 °C; 12 H,60 °C
    标题:Comparisons Of O-Acylation And Friedel-Crafts Acylation Of Phenols And Acyl Chlorides And Fries Rearrangement Of Phenyl Esters In Trifluoromethanesulfonic Acid: Effective Synthesis Of Optically Active Homotyrosines
    作者:Murashige,Ryo; Hayashi,Yuka; Ohmori,Syo; Torii,Ayuko; Aizu,Yoko; Et Al
    参考文献:Tetrahedron 日期:2011 卷标:67(3) 页码:641-649]

    2005-08-5 = 85-19-8 [标题:Reaction Conditions
    标题:Synthesis Of Hydroxy-Aryl Ketones As Uv Absorbers. V
    作者:Bhavsar,Madhury D.; Desai,Vijaykant B.
    参考文献:Man-Made Textiles In India 日期:1989 卷标:32(1) 页码:8-11]

    98-88-4 + 623-12-1 = 85-19-8
    反应条件:1.1 Catalysts: Aluminum Chloride Solvents: Dichloromethane; 12 H,Rt -> Reflux1.2 Reagents: Water; 20 Min,Cooled
    标题:Synthesis And Biological Evaluation Of Benzophenone Derivatives As Potential Hiv-1 Inhibitors
    作者:Song,Zhendong; Wang,Ping; Huang,Shanshan; Wang,Changyuan; Wang,Rui-Rui; Et Al
    参考文献:Medicinal Chemistry (Sharjah 日期:2017 卷标:13(4) 页码:398-405]

    98-88-4 = 85-19-8
    反应条件:1.1 Rt; 30 Min,Rt1.2 Catalysts: Fluoroflash; Rt; 4 H,80 °C
    标题:Catalytic Application Of Fluorous Silica Gel In Fries Rearrangement
    作者:Ghaffarzadeh,Mohammad; Ahmadi,Maryam
    参考文献:Journal Of Fluorine Chemistry 日期:2014 卷标:160 页码:77-81
(4-氯苯基)4-甲基苯甲酸酯置于盐酸,三氯化铝,溴体系中,化学反应 10.0H,反应生成 5-氯-2-羟基二苯甲酮
参考文献:Montfort,Bernard; Laude,Bernard; Vebrel,Joel,Bulletin De La Societe Chimique De France,1987,# 5,P. 848-854
标题:Montfort,Bernard; Laude,Bernard; Vebrel,Joel,Bulletin De La Societe Chimique De France,1987,# 5,P. 848-854

海关参考信息

专利信息


专利号:US-2023047214-A1
优先权日:2020-02-03
标题:Methods for microwave synthesis of degradable polymers for drug delivery
发明人:MURATOGLU ORHUN K; ORAL EBRU; GRINDY SCOTT
权利人:MASSACHUSETTS GEN HOSPITAL
摘要:Provided herein are methods of making degradable, additive-blended polymeric materials using microwave radiation and catalysts. The methods can include incorporation of therapeutic materials into the polymeric materials. There also are provided polymeric materials made by the methods and medical devices comprising the polymeric materials made by the methods.

专利号:US-6693091-B2
优先权日:2002-03-29
标 题 :Analogs of terpene trilactones from Ginkgo biloba for bioorganic and imaging studies
发明人:STROMGAARD KRISTIAN; SUEHIRO MAKIKO; NAKANISHI KOJI
权利人:UNIV COLUMBIA
摘要:A compound having the structure: n wherein R 1 is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; n wherein R 2 is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; n wherein R 3 is H or OH; n wherein R 4 is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; and n wherein at least one of R 1 , R 2 , R 3 , or R 4 is a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety. Optically pure enantiomers and salts of the compound are also described. Also, the synthesis of the compound, and uses of the compound, such as in a method for detecting the localization of, or identifying, receptors, enzymes or other targets, whether in a cell or in a subject.

专利号:EP-4206236-A1
优先权日:2021-12-28
标题 :Compounds, their synthesis and compositions comprising the compounds for enhanced deposition of polymers onto hair surfaces
发明人:BREAKSPEAR STEVEN; NÖCKER BERND; WEITZEL JOHANNA; PAEZ JULIETA; PEARSON SAMUEL; BRÜCK STEFAN; CAMPO ARANZAZU DEL
权利人:KAO CORP
摘要:The present invention is on polymers derivatized with an organic deposition-enhancing group for their enhanced deposition onto keratin fibers, especially human hair. The deposition-enhancing group is a di-hydroxyl phenolic compound with a spacer alkyl group bound to a reactive amine or carboxyl group, which reacts with one of the hydroxyl, carboxyl, primary and secondary amine groups on the polymeric backbone. The invention is on the method of synthesizing such compounds and compositions comprising the compounds.

专利号:US-9125843-B2
优先权日:2013-10-03
标 题 :Methods and compositions for improving the appearance of skin
发明人:PERNODET NADINE A; COLLINS DONALD F
权利人:PERNODET NADINE A; COLLINS DONALD F; ELC MAN LLC
摘要:A method for stimulating collagen synthesis in aging skin cells in need of treatment by topically applying a composition comprising at least one extract from Laminaria genus, at least one extract from the Narcissus genus, and at least one peptide that stimulates sirtuin 6 activity in the form of a peptide or a yeast extract where the peptide is component of the extract; and a treatment composition comprising at least one extract from Laminaria genus, at least one extract from the Narcissus genus; and at least one peptide that stimulates sirtuin 6 activity.

专利号:US-4244970-A
优先权日:1979-12-20
标题:Method of treating inflammation
发明人:DEWHIRST FLOYD E
权利人:FORSYTH DENTAL INFIRMARY
摘要:A method of treating inflammation and inhibiting prostaglandin synthesis employing 2-hydroxybenzophenone and substituted 2-hydroxybenzophenones.

专利号:WO-2021158704-A1
优先权日:2020-02-03
标题:Methods for microwave synthesis of degradable polymers for drug delivery
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合成参考文献


摘要:Lide, D.R., G.W.A. Milne (eds.). Handbook of Data on Organic Compounds. Volume I. 3rd ed. CRC Press, Inc. Boca Raton ,FL. 1994., p. V4: 3401
摘要:Hawley, G.G. The Condensed Chemical Dictionary. 9th ed. New York: Van Nostrand Reinhold Co., 1977., p. 197
摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
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