CAS: 3141-24-0; 2,3,5-Tribromothiophene

上下游产品

CAS号188290-36-0 Thiophene(SIV) | CAS号1003-09-4 2-溴噻吩 | CAS号3141-27-3 2,5-二溴噻吩 | CAS号3958-03-0 四溴噻吩 | CAS号7664-93-9 硫酸 | CAS号7726-95-6 溴素 | CAS号1006384-44-6 2,3-dibromo-5,2... | CAS号492-97-7 2,2'-双噻吩 | CAS号105125-00-6 3'-溴-2,2':5',2'... | CAS号3140-92-9 2,4-二溴噻吩 | CAS号3958-03-0 四溴噻吩 | CAS号7209-12-3 1-(4,5-DIBROMO-... | CAS号80775-52-6 1-(3,5-二溴噻吩-2-基)乙酮 | CAS号80775-47-9 3-Acetyl-2,4,5-... | CAS号62673-69-2 GSK-3β抑制剂VI | CAS号62673-70-5 2-chloro-1-(3,5...

噻吩置于氢溴酸,溴体系中,用85%的收率获得2,3,5-三溴噻吩
参考文献:立体与电子:多溴化噻吩的区域选择性交叉偶联
标题:立体与电子:多溴化噻吩的区域选择性交叉偶联
摘要:已经开发了 2,3,5-三溴噻吩的区域选择性交叉偶联方法,其中选择性芳基-芳基偶联发生在 5 位,产率高达 63%.α 位和 β 位反应性的差异允许顺序区域选择性偶联首先在 2 位,然后是 3 位.这种区域选择性交叉偶联允许对三官能化噻吩的生成进行前所未有的控制.(© Wiley-Vch Verlag Gmbh & Co. Kgaa,69451 Weinheim,Germany,2008)
Doi:10.1002/ejoc.200701148

专利信息

专利号:US-8835476-B2
优先权日:2005-03-04
标 题:Synthesis of novel antimicrobials
发明人：WU FAN; WEAVER DONALD; BARDEN CHRIS; MCMASTER CHRISTOPHER; BYERS DAVID; HENNEBERRY ANNETTE; BAN FUQIANG
权利人:WU FAN; WEAVER DONALD; BARDEN CHRIS; MCMASTER CHRISTOPHER; BYERS DAVID; HENNEBERRY ANNETTE; BAN FUQIANG
摘要:The synthesis and activity of novel LpxA inhibitors is described, these inhibitors present antibacterial activity. The compounds were designed based on a receptor model developed using the crystal structure of LpxA and are arranged to have a favorable binding interaction at the active site of the enzyme. In particular, the compounds present the following formula (I) where V, W, X, Y and Z can be independently C, S, N or O and P1, P2 and P3 are ligands to bind to the three points of the proposed pharmacophore model. They can be chosen from a variety of groups.

专利号:US-8450503-B2
优先权日:2002-08-09
标题:Photochromic and electrochromic compounds and methods of synthesizing and using same
发明人：BRANDA NEIL R; PETERS ANDREA; WIGGLESWORTH ANTHONY J
权利人:BRANDA NEIL R; PETERS ANDREA; WIGGLESWORTH ANTHONY J; SWITCH MATERIALS INC
摘要:This invention relates to novel photochromic and electrochromic monomers and polymers based on 1,2-dithienylcyclopentene derivatives and method of using and synthesizing same. The compounds are reversibly interconvertible between different isomeric forms under suitable photochromic or electrochromic conditions. The electrochromic conversion may be catalytic. The application also relates to ultra-high density homopolymers prepared using ring-opening methathesis polymerization (ROMP) where the central ring of the 1,2-bis(3-thienyl)-cyclopentene is incorporated directly into the polymer backbone. The monomer units may be readily functionalized to enable the synthesis of polymers with diverse structural and electronic properties. The compounds have many potential applications including high-density optical information storage systems, photoregulated molecular switches, reversible holographic systems, ophthalmic lenses, actinometry and molecular sensors, photochromic inks, paints and fibers and optoelectronic systems such as optical waveguides, Bragg reflectors and dielectric mirrors.

专利号:US-9045462-B2
优先权日:2012-08-17
标 题 :Synthesis of an antiviral compound
发明人：EVANS JARED WAYNE; FUJIMORI SHINJI; HUYNH GRACE M; LIU QI; TERESK MARTIN GERALD
权利人:GILEAD SCIENCES INC
摘要:The present disclosure provides processes for the preparation of a compound of Formula I: n nwhich is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of formula.

专利号:US-8927741-B2
优先权日:2012-08-17
标 题 :Synthesis of an antiviral compound
发明人：WATKINS WILLIAM JOHN; LIU QI
权利人:GILEAD SCIENCES INC
摘要:The present disclosure provides a processes for the preparation of a compound of Formula I: n nwhich is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of Formula I.

专利号:US-8759544-B2
优先权日:2012-08-17
标 题:Synthesis of an antiviral compound

专利号:US-6852711-B2
优先权日:1998-09-11
标题:HIV protease inhibitors
发明人：BOYER JR FREDERICK EARL; DOMAGALA JOHN MICHAEL; ELLSWORTH EDMUND LEE; GAJDA CHRISTOPHER ANDREW; HAGEN SUSAN ELIZABETH; LOVDAHL MICHAEL JAMES; LUNNEY ELIZABETH ANN; MARKOSKI LARRY JAMES; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
权利人:AGOURON PHARMA
摘要:The present invention relates to novel dihydropyrones with tethered heterocycles having improved pharmacologic properties which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The dihydropyrones are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of the dihydropyrones and intermediates useful in the preparation of the final compounds.