
物理性质
- 熔点136-144 °C
- 沸点442.3±55.0 °C at 760 mmHg
- 闪点221.3±31.5 °C
- 密度1.6±0.1 g/cm3
- PSA:86.34
- LogP:-0.43
- 折射率1.706
- 蒸汽压0.0±1.1 mmHg at 25°C
- 敏感性常温常压下稳定,避免与强氧化剂接触。
- 外观形态无色晶体
- 储存条件密封保存储存,储存于阴凉、干燥环境的库房。远离氧化剂。
- 产品应用吡虫啉(105827-78-9)的用途:其属于硝基亚甲基类内吸杀虫剂,选择性抑制昆虫神经系统中的烟酸乙酰胆碱酯酶受体,与其极高的竞争性结合从而破坏昆虫的中枢神经的正常传导,使之神经麻痹后死亡.吡虫啉是一种新型高效内吸杀虫剂,作用于烟碱乙酰胆碱受体,干扰昆虫神经系统的刺激传导,引起神经通路的阻塞.这种阻塞造成神经递质乙酰胆碱在突触部位的积累,从而导致昆虫麻痹,并最终死亡.其作用方式主要为胃毒和触杀,兼具内吸活性,适合于土壤,种子处理及颗粒施用.该药结构新颖,与传统的杀虫剂无交互抗性.持续期较长,对蚜虫,叶蝉,飞虱,粉虱等刺吸式口器害虫有很好的防治效果.对蚯蚓和蜘蛛等有益生物较安全,用于叶面施用时,特别是在花期,对蜜蜂高毒,但种子处理时对蜜蜂无毒,对地下水安全.用于防治刺吸式口器害虫,如蚜虫,叶蝉,飞虱,蓟马,粉虱及其抗性品系.对鞘翅目,双翅目和鳞翅目也有效.对线虫和红蜘蛛无活性.由于其优良的内吸性,特别适于种子处理和以颗粒剂施用.在禾谷类作物,玉米,水稻,马铃薯,甜菜和棉花上可早期持续防治害虫,上述作物及柑橘,落叶果树,蔬菜等生长后期的害虫可叶面喷雾.叶面喷雾对黑尾叶蝉,飞虱类(稻褐飞虱,灰飞虱,白背飞虱),蚜虫类(桃蚜,棉蚜)和蓟马类(温室条篱蓟马)有优异的防效,优于噻嗪酮,醚菊酯,抗蚜威和杀螟丹.
欧盟法规
C&L通报REACH预注册上下游产品
CAS号101990-44-7 N-[(6-Chloro-3-... | CAS号5465-96-3 2-硝基亚氨基咪唑烷 | CAS号70258-18-3 2-氯-5-氯甲基吡啶 | CAS号616-45-5 2-吡咯烷酮 | CAS号5326-23-8 6-氯烟酸 | CAS号6271-78-9 6-氯烟酰胺 | CAS号23100-12-1 6-氯吡啶-3-甲醛 | CAS号463-04-7 亚硝酸戊酯 | CAS号625-74-1 2-甲-1-硝丙烷 | CAS号120868-66-8 1-((6-氯吡啶-3-基)甲... | CAS号115970-17-7 DESNITROIMIDACLOPRID专利信息
专利号:US-2005004225-A1
优先权日:2003-04-16
标题:Oxidoreductase inhibitors and methods of screening and using thereof
发明人:BALENDIRAN GANESARATNAM K
摘要:The present invention relates to 1) the design and synthesis of analogs to glutathione conjugates which bind to or interact with aldose reductase (AR) through unique conformations that are distinctly different from the substrates and inhibitors of AR which are members of sugar metabolism; 2) the screening of the analogs to identify those that interact with or inhibit or enhance the activity of AR; and 3) the use of AR ligands, AR inhibitors (AR antagonsits) or AR enhancer (AR agonists) in the detection of AR activity, the modulation of AR activity, and the treatment of conditions in a subject in need of modulating AR activity. Such conditions include but not limited to cardiovascular disease, diabetes, artheriosclerosis, cancer, neoplasm, obesity, cataract, retinopathy, keratopathy, nephropathy, neurosis, thrombosis, faulty union of corneal injury and neuropathy. Examples of the treatment include the use of fibrates as AR inhibitors to treat these conditions.
专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.
专利号:US-2016073631-A1
优先权日:2013-03-04
标 题 :Process for the preparation of dihydropyrrole derivatives
发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).
专利号:US-9233920-B2
优先权日:2010-06-11
标题 :Process for the preparation of dihydropyrrole derivatives
发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS; SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R 1 is chlorodifluoromethyl or trifluoromethyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R 1 and R 2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R 1 and R 2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).
专利号:US-11751567-B2
优先权日:2021-09-23
标 题:Steroidal piperidone derivative, synthesis method, and use thereof
发明人:SHI BAOJUN; JIANG WEIQI; MA SHICHUANG; HU YUXIAO; WANG QIANGPING
权利人:UNIV NORTHWEST A&F
摘要:A steroidal piperidone derivative, a synthesis method, and a use thereof are provided. The steroidal piperidone derivative has a chemical structure shown in general formula (1) or general formula (2), where R is any one selected from the group consisting of alkyl, phenyl, substituted phenyl, and a heterocycle. In the synthesis method of the steroidal piperidone derivative, dehydroepiandrosterone (DHEA) is used as a basic raw material to prepare the steroidal piperidone derivative of the present disclosure through a series of reactions. A product prepared by the synthesis method has a high yield and is easily separated, and thus the synthesis method is the optimal method for preparing the steroidal piperidone derivative of the present disclosure. The present steroidal piperidone derivative exhibits prominent toxic activity against sucking pests, such as aphids, spider mites, rice planthoppers, and B. tabaci, and can be used for the control of a plant pest.
专利号:US-10906880-B2
优先权日:2016-01-26
标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
权利人:UNIV NANKAI
摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.