CAS: 20776-48-1; 2-Amino-6-Bromobenzoic Acid

上下游产品

CAS号20780-72-7 4-溴靛红 | CAS号38876-67-4 2-溴-6-硝基苯甲酸 | CAS号38792-45-9 2-acetamido-6-b... | CAS号67866-91-5 3-bromo-2-methy... | CAS号55289-36-6 2-甲基-3-溴苯胺 | CAS号55289-35-5 2-溴-6-硝基甲苯 | CAS号77603-45-3 6-溴靛红 | CAS号147006-47-1 5-溴喹唑啉-4-酮 | CAS号861106-92-5 (2-氨基-6-溴苯基)甲醇 | CAS号864845-15-8 4-溴-1H-吲唑-3(2H)-酮 | CAS号959237-01-5 5-溴喹唑啉-2,4(1H,3H)-二酮

2-溴-6-硝基甲苯置于盐酸,Potassium Permanganate,Magnesium Sulfate,Tin(Ll) Chloride体系中,用 乙醇,水 用作溶剂,化学反应 57.17H,反应生成2-氨基-6-溴苯甲酸
参考文献:Synthesis Of 123I-Labelled Analogues Of Imidazobenzodiazepine Receptor Ligands.
标题:Synthesis Of 123I-Labelled Analogues Of Imidazobenzodiazepine Receptor Ligands.
摘要:溴代或碘代异丁烯酸酐与 N-甲基甘氨酸,L-脯氨酸或 D-脯氨酸反应,得到溴代或碘代的 1,4-苯并二氮杂环庚二酮. 或碘代的 1,4-苯并二氮杂环庚二酮,在与乙基或叔丁基异氰基乙酸酯缩合后 异氰基乙酸乙酯或异氰基乙酸叔丁酯缩合后,得到溴代或碘代咪唑苯并 碘咪唑并二氮杂卓羧酸酯.这些芳基卤化物 在(三苯基膦)存在下,用双(三丁基锡)将这些芳基卤化物转化为相应的三丁基锡烷. 三苯基膦)钯(0)的存在下,用双(三丁基锡)将这些芳基卤化物转化为相应的三丁基锡烷,然后用 在氯胺-T 的存在下,用(123I)碘化钠处理锡烷,得到所需的 123I 标记. 得到所需的 123I 标记的类似物 咪唑苯并二氮杂卓受体配体氟马西尼和溴他西尼.
Doi:10.1071/ch99135

专利信息

专利号:US-4154745-A
优先权日:1977-05-02
标题:Isobenzofuran route to anthracycloquinones
发明人：KENDE ANDREW S; TSAY YUH-GENG
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain tetracyclic quinones. In particular, there is provided a novel route to the synthesis of (±)-7-deoxydaunomycinone and analogs thereof which includes the provision of novel tetrahydronaphthoquinones and tetracyclic quinone intermediates. The compounds of the present invention are provided through a route comprising a Diels-Alder addition of certain isobenzofurans to certain novel tetrahydronaphthoquinones. The products of the synthetic route provided herein may be converted into compounds of known antibiotic and antineoplastic activity.

专利号:CN-115010671-A
优先权日:2022-07-20
标题:One-step synthesis method of 2-substituted quinazolinone

专利号:CN-115010671-B
优先权日:2022-07-20
标 题:One-step synthesis method of 2-substituted quinazolinone