CAS: 4755-77-5; Ethyl Oxalyl Monochloride

相似化合物

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上下游产品

CAS号95-92-1 草酸二乙酯 | CAS号1906-57-6 乙基草酸钾 | CAS号79-37-8 草酰氯 | CAS号64-17-5 乙醇 | CAS号617-37-8 草酸单乙酯 | CAS号91467-21-9 2,4-Oxazolidine... | CAS号6957-89-7 Acetic acid,2,2... | CAS号109-92-2 乙烯基乙醚 | CAS号10026-13-8 五氯化磷 | CAS号111686-63-6 ethyl 1-oxois°C... | CAS号109735-80-0 ethyl 1H-perimi... | CAS号33656-65-4 ETHYL 2-(1-NAPH... | CAS号73790-09-7 (萘-2-基)(氧代)乙酸乙酯 | CAS号40140-16-7 乙酯4-甲氧基苯并基甲酸盐 | CAS号66644-69-7 ETHYL 2-METHOXY... | CAS号383363-34-6 ETHYL 4-BROMO-2... | CAS号40019-21-4 3-甲基-1,2,4-恶二唑-... | CAS号34906-84-8 2-(4-异丙基苯基)-2-氧代乙酸乙酯 | CAS号32137-76-1 1,3-苯并噻唑-2-羧酸乙酯

草酸二乙酯置于五氯化磷体系中,化学反应生成 草酰氯单乙酯
参考文献:Peratoner; Strazzeri,Gazzetta Chimica Italiana,1891,Vol. 21 I,P. 306
标题:Peratoner; Strazzeri,Gazzetta Chimica Italiana,1891,Vol. 21 I,P. 306

专利信息

专利号:WO-2018154596-A1
优先权日:2017-02-22
标 题 :Process for synthesis of tiotropium bromide monohydrate
发明人：REDDY G NITHUN; REDDY G SAMHITHA; REDDY G MADAALASA; RAMANI M; REDDY G PRATAP
权利人:GBR LABORATORIES PVT LTD; RACHANA PHARMA TECH
摘要:Provided herein is a process for synthesis of tiotropium bromide wherein the coupling of scopine with 2, 2-dithienyl glycolate is achieved by a two step process under mild conditions.

专利号:WO-2014072884-A1
优先权日:2012-11-12
标 题 :Process for the synthesis of apixaban
发明人：JAYARAMAN VENKAT RAMAN; PATEL NILAV; BORSANIYA MANOJ; KANZARIYA KAMLESH; RANA PIYUSH; SHAH SUDHIR; PANCHASARA DINESH; TOMER SANJIV
权利人:ALEMBIC PHARMACEUTICALS LTD; JAYARAMAN VENKAT RAMAN
摘要:The present invention relates to the Process for the preparation of Apixaban and novel intermediates useful in the synthesis of Apixaban (I).

专利号:US-9475814-B2
优先权日:2011-10-03
标题:Chiral N-acyl-5,6,7(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof
发明人：HOVEYDA HAMID R; DUTHEUIL GUILLAUME; FRASER GRAEME L; ROY MARIE-ODILE; EL BOUSMAQUI MOHAMED; BATT FREDERIC
权利人:EUROSCREEN SA
摘要:The present invention relates to novel compounds of Formula I and their use in therapeutic treatments. The invention further relates to a novel chiral synthesis of 5,6,7,(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines using N-sp3 protective groups. The invention also provides intermediates for use in the synthesis of compounds of Formula I.

专利号:US-6225329-B1
优先权日:1998-03-12
标 题 :Modulators of protein tyrosine phosphatases (PTPases)
发明人：RICHTER LUTZ STEFAN; ANDERSEN HENRIK SUNE; VAGNER JOSEF; JEPPESEN CLAUS BEKKER; MOELLER NIELS PETER HUNDAHL; BRANNER SVEN; SU JING; BAKIR FARID; JUDGE LUKE MILBURN
权利人:NOVO NORDISK AS
摘要:The present invention provides novel compounds of Formula 1, compositions containing these compounds, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like, n wherein A, R 1 , R 2 , R 3 , R 4 , R 16 and R 17 are as defined in the specification. The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimer's disease and schizophrenia, and infectious diseases.

专利号:US-2005119332-A1
优先权日:1998-03-12
标 题 :Substituted thiophene compounds as modulators of protein tyrosine phosphatases (PTPases)
发明人：JEPPESEN LONE; ANDERSEN HENRIK S; OLSEN OLE H; JUDGE LUKE M; HOLSWORTH DANIEL D; BAKIR FARID; AXE FRANK U; GE YU
摘要:The present invention provides novel compounds of formula 1a, n nnovel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimer's disease and schizophrenia, and infectious diseases.

专利号:WO-9946244-A1
优先权日:1998-03-12
标题 :Modulators of protein tyrosine phosphatases (ptpases)
发明人：JEPPESEN LONE; ANDERSEN HENRIK SUNE; OLSEN OLE HVILSTED; JUDGE LUKE MILBURN; HOLSWORTH DANIEL DALE; BAKIR FARID; AXE FRANK URBAN; GE YU
权利人:NOVO NORDISK AS; ONTOGEN CORP
摘要:The present invention provides novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimer's disease and schizophrenia, and infectious diseases.