专利号:US-2011263870-A1 优先权日:2010-04-23 标题 :Novel pyrrole derivatives and their synthesis 发明人:PRADHAN BRAJA SUNDAR 权利人:HELVETICA IND P LTD 摘要:The present invention relates to two novel pyrrole derivatives [3-Phenyl-4-(phenylcarbamoyl)-2-(4-fluorophenyl)-5-(1-methylethyl)-pyrrole-1-yl]methyl(diphenyl)phosphine oxide and Diethyl [3-Phenyl-4-(phenylcarbamoyl)-2-(4-fluorophenyl)-5-(1-methylethyl)-pyrrole-1-yl]methylphosphonate. These pyrrole derivatives can be used as intermediates for the synthesis of the anticholesterol drug atorvastatin.
专利号:US-6989401-B2 优先权日:2000-07-19 标题:Sulfonic acid derivatives of hydroxamic acids and their use as medicinal products 发明人:MAEDA KAZUHIRO; SONDA SHUJI; TAKEMOTO TADAHIRO; GOTO TOMOKAZU; KOBAYASHI FUJIO; KAJII MASAHIKO; KOMORITA NARUYASU; HIRAYAMA FUMIHIRO 权利人:MITSUBISHI PHARMA CORP 摘要:The present invention relates to a novel sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof. More particularly, the present invention relates to a sulfonic acid derivative of hydroxamic acid or a pharmacologically acceptable salt thereof, which is useful as an inhibitor of lipopolysaccharides (LPS). In addition, the present invention relates to a novel intermediate compound useful for the synthesis of this sulfonic acid derivative of hydroxamic acid.
专利号:US-11229590-B2 优先权日:2018-10-25 标题 :Sunscreen formulation 发明人:SUN YIMIN 权利人:SUN YIMIN 摘要:The present invention relates to the synthesis of new classes of sunscreen agents, the usage of such sunscreen agents in sunscreen formulations aiming at reduction of sunscreen agents' skin penetration, and a formulation technology using existing sunscreen agents aiming at reduction of sunscreen agents' skin penetration, therefore improving the bio-safety of the sunscreen products.
专利号:WO-2024130689-A1 优先权日:2022-12-23 标 题:2-fluorobiphenyl-4-acetic acid derivative, preparation method therefor, and use thereof 发明人:CHEN YUXIN; CHEN MINGXIA; YAO WENJUN 权利人:JIANGSU PROTELIGHT PHARMACEUTICAL & BIOTECHNOLOGY CO LTD 摘要:Disclosed are a 2-fluorobiphenyl-4-acetic acid derivative, a preparation method therefor, and use thereof. The structural formula of the 2-fluorobiphenyl-4-acetic acid derivative is set forth in formula I. The compound can be prepared by means of an artificial synthesis method, having a broad-spectrum anti-tumor effect, prolonging the survival period of tumor patients and improving their survival quality. The compound has stable therapeutic effects, low toxicity and easy acceptance by a human body, and is applicable to the treatment of most cancers, thus exhibiting certain advantages over currently available anti-tumor drugs.
专利号:JP-2001503782-A 优先权日:1996-11-22 标题 :Method and compound for inhibiting release of beta-amyloid peptide and / or its synthesis
专利号:RU-2131425-C1 优先权日:1994-04-25 标 题:Hydroxamic acid derivatives, method of their synthesis, drug and method of its preparing
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合成参考文献
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