CAS: 638-02-8; 2,5-Dimethylthiophene

上下游产品

CAS号110-13-4 2,5-己二酮 | CAS号625-86-5 2,5-二甲基呋喃 | CAS号13679-70-4 5-甲基-2-噻吩甲醛 | CAS号592-46-1 2,4-己二烯 | CAS号592-43-8 2-己烯 | CAS号554-14-3 2-甲基噻吩 | CAS号80243-14-7 3-(1,1-dimethyl... | CAS号7647-01-0 盐酸 | CAS号1151942-86-7 [(η5-C5Me5)IrCl... | CAS号4282-31-9 噻吩-2,5-二羧酸 | CAS号5368-70-7 噻吩-2-碳酸酯 | CAS号766-58-5 3-Chloromethyl-... | CAS号80818-32-2 3,3'-methyleneb... | CAS号31772-43-7 2-氯-1-(2,5-二甲基噻... | CAS号40323-88-4 2-乙基-5-甲基噻吩 | CAS号55735-23-4 3-ethyl-2,5-dim... | CAS号108852-05-7 4,6,12,14-tetra... | CAS号143756-02-9 6,8-dimethyl-1,... | CAS号513-81-5 2,3-二甲基-1,3-丁二烯

2,5-二甲基呋喃置于盐酸,硫化氢,18O-2,5-Dimethylfuran体系中,用 乙醇 作为反应溶剂,化学反应 1.0H,反应生成 2,5-二甲基噻吩
参考文献:Study Of The Mechanism Of Recyclization Of Furans Into Thiophenes And Selenophenes In Conditions Of Acid Catalysis. 6. Experiments With Labeled Atoms. Quantum Chemical Calculations Of Intermediates Of Recyclization And Hydrolysis
标题:Study Of The Mechanism Of Recyclization Of Furans Into Thiophenes And Selenophenes In Conditions Of Acid Catalysis. 6. Experiments With Labeled Atoms. Quantum Chemical Calculations Of Intermediates Of Recyclization And Hydrolysis
摘要:
DOI:10.1007/bf02253158

专利信息

专利号:US-6413957-B1
优先权日:1998-04-21
标题:Methods of inhibiting cell proliferation using indeno [1,2-c]pyrazol-4-ones
发明人：NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; YUE EDDY W
权利人:BRISTOL MYERS SUIBB PHARMA COM
摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): n that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G. This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

专利号:US-9802952-B2
优先权日:2013-07-15
标 题:Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives
发明人：KOPETZKI DANIEL; MCQUADE DAVID TYLER; SEEBERGER PETER H; GILMORE KERRY
权利人:MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V; MAX-PLANK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V
摘要:The present invention is directed to a method for continuous production of dihydroartemisinin and also artemisinin derivatives derived from dihydroartemisinin by using artemisinin or dihydroartemisinic acid (DHAA) as starting material as well as to a continuous flow reactor for producing dihydroartemisinin as well as the artemisinin derivatives. It was found that the reduction of artemisinin to dihydroartemisinin in a continuous process requires a special kind of reactor and a special combination of reagents comprising a hydride reducing agent, at least one activator such as an inorganic activator, at least one solid base, at least one aprotic solvent and at least one C 1 -C 5 alcohol.

专利号:US-9012600-B2
优先权日:2012-02-13
标 题:Synthesis of dioxyheterocycle-based polymers
发明人：REYNOLDS JOHN R; ARROYAVE-MONDRAGON FRANK ANTONIO
权利人:UNIV FLORIDA
摘要:A method of polymerization for the preparation of conjugated polymers and copolymers comprising dioxypyrrole and/or dioxyfuran repeating units involves the halogen, N-haloimide, or N-haloamine promoted polymerization of monomers and/or oligomers comprising one or more dioxypyrrole and/or dioxyfuran units. The polymerization can be carried out over a wide range of temperatures and can be carried out with or without a solvent. The monomers allow the preparation of polymers having an oligomeric repeating unit comprising a conjugated unit other than a dioxypyrrole or dioxyfuran that is bound to two dioxypyrrole or dioxyfuran units.

专利号:US-8034895-B2
优先权日:2004-02-04
标题 :Conjugated thiophenes having conducting properties and synthesis of same
发明人：SKENE WILLIAM G
权利人:UNIV MONTREAL
摘要:The present invention relates to conjugated oligomers and polymers comprising aromatic thiophene cores. The conjugated materials are obtained by simple and efficient condensation of an aryl diamine and an aryl dialdehyde or a bifunctional aryl moiety comprising both an aldehyde and an amine. Condensation of the complementary moieties at temperatures ranging from ambient to refluxing temperatures in various solvents resulted in conjugated oligomers and polymers that can subsequently be cast into thin films. Oligomerization and polymerization can be done under mild conditions with removal of the resulting water bi-product responsible for shifting the equilibrium in favor of the conjugated products. The resulting conjugated compounds can be made conducting with dopants affording electrically conducting materials of either p-type or n-type conductors depending on the dopant selected.

专利号:US-5849950-A
优先权日:1995-05-29
标题:Preparation of glycine-N,N-diacetic acid derivatives
发明人：GREINDL THOMAS; OFTRING ALFRED; BRAUN GEROLD; WILD JOCHEN; POTTHOFF-KARL BIRGIT; SCHUH GEORG
权利人:BASF AG
摘要:Glycine-N,N-diacetic acid derivatives I ##STR1## where R is unsubstituted or substituted alkyl, alkenyl, alkoxylate groups, phenylalkyl, phenyl, a heterocyclic ring or a radical of the formula ##STR2## where A is an alkylene bridge or a chemical bond, and M is hydrogen, alkali metal, alkaline earth metal, ammonium or substituted ammonium in the appropriate stoichiometric amounts, n are prepared by reacting n A) corresponding 2-substituted glycines or 2-substituted glycinonitriles or doubled glycines of the formula ##STR3## or doubled glycinonitriles of the formula ##STR4## or precursors of the glycine derivatives named as starting material with formaldehyde and hydrogen cyanide in aqueous medium at a pH of from 0 to 11 or n B) iminodiacetonitrile or iminodiacetic acid with appropriate monoaldehydes of the formula R--CHO or dialdehydes of the formula OHC--A--CHO and hydrogen cyanide in aqueous medium at a pH of from 0 to 11 n and, where appropriate, subsequent hydrolysis of nitrile functionalities which are present, where the starting material used comprises unpurified raw material derived from the industrial synthesis of glycine derivatives or their precursors or of iminodiacetonitrile or iminodiacetic acid, or mother liquors produced in such syntheses.

专利号:US-8168745-B2
优先权日:2007-08-02
标 题:Process for the preparation of poly- and oligothiophenes on an industrial scale
发明人：HENNINGER BJOERN; RAUSCHER FRANK; MLECZKO LESLAW
权利人:HENNINGER BJOERN; RAUSCHER FRANK; MLECZKO LESLAW; BAYER TECHNOLOGY SERVICES GMBH
摘要:Process for industrial scale synthesis of poly- and oligothiophenes, which works in concentrated solution. In this process, a solution which comprises an organometallic thiophene reagent is added to a second solution which comprises a catalyst.