CAS: 117572-79-9; 3-Bromo-4-Methoxybenzonitrile

该化合物是一种有机化合物,其特点是芳香结构,包括一个溴原子和一个附于苯环的甲氧组,以及一个硝酸基功能组.溴原子的存在会引入一种卤素,它会影响化合物的再活性和极度.甲氧基组是一个电饱和组,它能够增强芳香环的核素性,使其对电极更具反应性.硝酸盐组(-CN)有助于该化合物的总体极性,并能够参与各种化学反应,例如核分裂性添加.该化合物通常用于有机合成,并可作为生产药物或农用化学的中间体.其物理特性,如熔点,沸点和溶性,受到现有功能组和整体分子结构的影响.应当参考安全数据,以便处理,因为卤化化合物可能会对健康造成危害.

结构式图片

相似化合物

34841-06-0 99-58-1 3336-39-8

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CAS号34841-06-0 3-溴-4-甲氧基苯甲醛 | CAS号137042-67-2 3-bromo-4-metho... | CAS号2315-86-8 3-溴-4-羟基苯甲腈 | CAS号74-88-4 碘甲烷 | CAS号34039-30-0 2-Bromo-1-metho... | CAS号874-90-8 4-甲氧基苯甲腈 | CAS号5197-28-4 2-溴-4-硝基苯甲醚 | CAS号143-33-9 氰化钠 | CAS号191602-76-3 5-(3-溴-4-甲氧基苯基)... | CAS号247254-47-3 3-溴-4-甲氧基苄胺 | CAS号612833-37-1 2-甲氧基-5-氰基苯硼酸 | CAS号40757-12-8 5-氰基-2-甲氧基苯甲酸甲酯

合成工艺路线路线简述

    对甲苯甲醚置于氢溴酸,双氧水,氨,碘体系中,用 四氯化碳,水,乙腈 用作溶剂,化学反应 5.0H,以99%的收率获得3-溴-4-甲氧基苯甲腈
    参考文献:使用无机无金属试剂将甲基芳烃一锅法转化为芳香腈
    标题:使用无机无金属试剂将甲基芳烃一锅法转化为芳香腈
    摘要:通过用水溶液处理,各种甲基芳烃以非常好到中等的收率转化为相应的芳香腈.Hbr 和水溶液.H2O2,然后与分子碘和水溶液反应.氨在一锅程序中.本反应是一种有用的,实用的,无过渡金属和无有机试剂的方法,用于从甲基芳烃制备芳香腈.
    Doi:10.1002/ejoc.201402270

    海关参考信息

    专利信息


    专利号:WO-03000690-A1
    优先权日:2001-06-25
    标题:Synthesis of heterocyclic compounds employing microwave technology
    发明人:MAJID TAHIR NADEEM; DEPRETS STEPHANIE D; PEDGRIFT BRIAN L
    权利人:AVENTIS PHARMA INC; MAJID TAHIR NADEEM; DEPRETS STEPHANIE D; PEDGRIFT BRIAN L
    摘要:This invention provides for processes for preparing compounds of the formula (I) comprising employing microwave energy.

    专利号:US-9550000-B2
    优先权日:2011-09-09
    标题 :Compositions, methods, and systems for the synthesis and use of imaging agents
    发明人:ROBINSON SIMON P; YU MING
    权利人:ROBINSON SIMON P; YU MING; LANTHEUS MEDICAL IMAGING INC
    摘要:The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs. In some embodiments, methods and compositions for assessing perfusion and innervation mismatch in a portion of a subject are provided.

    专利号:US-7951827-B2
    优先权日:2005-05-05
    标 题:Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles
    发明人:TIDWELL RICHARD R; BAKUNOVA SVETLANA M; BAKUNOV STANISLAV; PATRICK DONALD A
    权利人:UNIV NORTH CAROLINA
    摘要:Novel dicationic 3,5-diphenylisoxazole compounds are described. Synthetic routes to these novel compounds are provided. Several of the compounds displayed in vitro activity versus Trypanosoma brucei brucei and Plasmodium falciparum comparable to that of furamidine. A majority of the novel compounds also were less toxic to VERO cells than furamidine.

    专利号:US-2025026766-A1
    优先权日:2022-01-12
    标题 :Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors
    发明人:LI JING; XU WENQING; WANG ZHIWEI
    权利人:BEIGENE LTD
    摘要:The present invention relates to compounds containing thiazolopyridyl amide structure, the process for their synthesis, as well as the use of such compounds for inhibiting DNA Polymerase Theta (Pol Theta), and in the treatment of various diseases including cancers.

    专利号:US-2006264487-A1
    优先权日:2005-05-05
    标 题:Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles

    专利号:US-2022339303-A1
    优先权日:2011-09-09
    标题 :Compositions, methods, and systems for the synthesis and use of imaging agents
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    合成参考文献


    参考文献:10.1055/s-0029-1218388
    摘要:Augustine J, Atta R, Ramappa B, Boodappa C. Propylphosphonic Anhydride (T3P®): A Remarkably Efficient Reagent for the One-Pot Transformation of Aromatic, Heteroaromatic, and Aliphatic Aldehydes to Nitriles. Synlett. 2009 Nov 27;2009(20):3378–82. doi: 10.1055/s-0029-1218388.
    参考文献:10.1055/s-0037-1611863
    摘要:Mittal R, Awasthi SK. Recent Advances in the Synthesis of 5-Substituted 1H-Tetrazoles: A Complete Survey (2013–2018). Synthesis. 2019 Jul 01;51(20):3765–83. doi: 10.1055/s-0037-1611863.
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