专利号:WO-03000690-A1 优先权日:2001-06-25 标题:Synthesis of heterocyclic compounds employing microwave technology 发明人:MAJID TAHIR NADEEM; DEPRETS STEPHANIE D; PEDGRIFT BRIAN L 权利人:AVENTIS PHARMA INC; MAJID TAHIR NADEEM; DEPRETS STEPHANIE D; PEDGRIFT BRIAN L 摘要:This invention provides for processes for preparing compounds of the formula (I) comprising employing microwave energy.
专利号:US-9550000-B2 优先权日:2011-09-09 标题 :Compositions, methods, and systems for the synthesis and use of imaging agents 发明人:ROBINSON SIMON P; YU MING 权利人:ROBINSON SIMON P; YU MING; LANTHEUS MEDICAL IMAGING INC 摘要:The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs. In some embodiments, methods and compositions for assessing perfusion and innervation mismatch in a portion of a subject are provided.
专利号:US-7951827-B2 优先权日:2005-05-05 标 题:Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles 发明人:TIDWELL RICHARD R; BAKUNOVA SVETLANA M; BAKUNOV STANISLAV; PATRICK DONALD A 权利人:UNIV NORTH CAROLINA 摘要:Novel dicationic 3,5-diphenylisoxazole compounds are described. Synthetic routes to these novel compounds are provided. Several of the compounds displayed in vitro activity versus Trypanosoma brucei brucei and Plasmodium falciparum comparable to that of furamidine. A majority of the novel compounds also were less toxic to VERO cells than furamidine.
专利号:US-2025026766-A1 优先权日:2022-01-12 标题 :Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors 发明人:LI JING; XU WENQING; WANG ZHIWEI 权利人:BEIGENE LTD 摘要:The present invention relates to compounds containing thiazolopyridyl amide structure, the process for their synthesis, as well as the use of such compounds for inhibiting DNA Polymerase Theta (Pol Theta), and in the treatment of various diseases including cancers.
专利号:US-2006264487-A1 优先权日:2005-05-05 标 题:Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles
专利号:US-2022339303-A1 优先权日:2011-09-09 标题 :Compositions, methods, and systems for the synthesis and use of imaging agents
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