CAS: 2620-44-2; 5-Nitrobenzo[d][1,3]Dioxole

上下游产品

CAS号274-09-9 1,2-亚甲二氧基苯 | CAS号94839-07-3 3,4-(亚甲基二氧基)苯硼酸 | CAS号7228-38-8 5-氯-1,3-苯并二氧杂环戊 | CAS号3162-29-6 3',4'-(亚甲基二氧)苯乙酮 | CAS号14268-66-7 3,4-亚甲二氧基苯胺 | CAS号75-11-6 二碘甲烷 | CAS号3316-09-4 4-硝基儿茶酚 | CAS号94-53-1 胡椒酸 | CAS号133-03-9 EPISESAMIN | CAS号120-57-0 胡椒醛 | CAS号39835-14-8 2-羟基-4-硝基苯腈 | CAS号636-93-1 5-硝基愈创木酚 | CAS号130400-94-1 3-hydroxy-4-iso... | CAS号3316-09-4 4-硝基儿茶酚 | CAS号7251-09-4 4-氨基-2-甲氧基苯腈 | CAS号101084-96-2 2-甲氧基-4-硝基苯甲腈 | CAS号14268-66-7 3,4-亚甲二氧基苯胺 | CAS号121-88-0 2-氨基-5-硝基苯酚 | CAS号13067-19-1 N-(苯并[d][1,3]二氧... | CAS号59856-06-3 N-(2,3-二氢-1H-茚-...

胡椒环置于六氟异丙醇,四丁基亚硝酸铵体系中,用 乙腈 用作溶剂,化学反应 0.83H,以28%的收率获得1,2-亚甲基双氧-4-硝基苯
参考文献:亚硝酸盐电化学硝化
标题:亚硝酸盐电化学硝化
摘要:芳烃,苯酚和苯胺衍生物的硝化是通过使用廉价的石墨电极将亚硝酸盐作为安全硝基源电化学氧化为no 2 /n 2 O 4来完成的.乙腈中化学计量的 1,1,1-3,3,3-六氟异丙-2-醇 (Hfip) 通过溶剂控制可显着提高产率.该反应具有可扩展性,已论证了 20 个实例,产率高达 88%.
Doi:10.1002/cssc.202102053

专利信息

专利号:US-2015038591-A1
优先权日:2002-05-31
标 题:Compounds, compositions and methods for the treatment of tauopathies
发明人：SNOW ALAN D; CAM JUDY A; CASTILLO GERARDO; HU QUBAI; LAKE THOMAS
权利人:PROTEOTECH INC
摘要:Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of tauopathies, such as Alzheimer's disease and Parkinson's disease, and the manufacture of medicaments for such treatment.

专利号:US-7919530-B2
优先权日:2002-05-31
标 题 :Compounds, compositions, and methods for the treatment of synucleinopathies
发明人：ESPOSITO LUKE A; CUMMINGS JOEL; HUDSON F MICHAEL; SNOW ALAN D
权利人:PROTEOTECH INC
摘要:Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of synucleinopathies, such as Parkinson's disease, and the manufacture of medicaments for such treatment.

专利号:US-7601876-B2
优先权日:2002-05-31
标题 :Compounds, compositions and methods for the treatment of amyloid diseases such as systemic AA amyloidosis
发明人：SNOW ALAN D; NGUYEN BETH P; CASTILLO GERARDO M; SANDERS VIRGINIA J; LAKE THOMAS P; LARSEN LESLEY; WEAVERS REX T; LORIMER STEPHEN D; LARSEN DAVID S; COFFEN DAVID L; COFFEN CHARLOTTE
权利人:PROTEOTECH INC
摘要:Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, AA/SAA amyloidosis, such as observed in systemic AA amyloidosis and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.

专利号:EP-4245856-B1
优先权日:2022-03-15
标题 :Synthesis of functional unspecific peroxidases using a non-fungal eukaryotic cell-free system
发明人：WALTER RUBEN; KUBICK STEFAN; ZEMELLA ANNE
权利人:FRAUNHOFER GES FORSCHUNG

专利号:US-6417195-B1
优先权日:1999-02-22
标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：LEBL MICHAL
权利人:LION BIOSCIENCE AG
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.

专利号:US-5874443-A
优先权日:1995-10-19
标 题:Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：KIELY JOHN S; GRIFFITH MICHAEL C
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinolines as well as novel libraries comprised of many such compounds, and methods of synthesizing the libraries.