CAS: 4382-54-1; 5-Methoxyindole-2-Carboxylic Acid

上下游产品

CAS号4792-58-9 5-甲氧基吲哚-2-羧酸乙酯 | CAS号67929-86-6 5-甲氧基吲哚-2-羧酸甲酯 | CAS号591-31-1 3-甲氧基苯甲醛 | CAS号104-94-9 对甲氧基苯胺 | CAS号4346-59-2 4-methoxybenzen... | CAS号4792-57-8 (E)-ETHYL 2-(2-... | CAS号82204-34-0 3-(5-methoxy-2-... | CAS号36820-78-7 3-甲酰基-5-甲氧基-2-乙... | CAS号21778-77-8 (5-甲氧基-1H-吲哚-2-基)甲醇 | CAS号21778-81-4 5-甲氧基-1H-吲哚-2-甲醛 | CAS号28837-74-3 1H-Indole-2-car... | CAS号28837-78-7 (5-methoxy-1H-i... | CAS号67929-86-6 5-甲氧基吲哚-2-羧酸甲酯 | CAS号10601-19-1 5-甲氧基吲哚-3-甲醛 | CAS号1006-94-6 5-甲氧基吲哚 | CAS号651331-50-9 5-甲氧基-1-(4-甲氧基苯... | CAS号651331-66-7 10-[5-methoxy-1...

5-甲氧基吲哚-2-羧酸甲酯置于potassium Hydroxide体系中,用 二甲基亚砜 作为反应溶剂,化学反应 0.5H,反应生成 5-甲氧基吲哚-2-羧酸
参考文献:钯催化芳烃羧酸/酯与芳基溴化物的分子内脱羧偶联
标题:钯催化芳烃羧酸/酯与芳基溴化物的分子内脱羧偶联
摘要:给我一个戒指已经开发出一种有效的方法用于芳烃羧酸/酯与钯催化的芳基溴化物的分子内脱羧偶联(参见方案).从合成的观点来看,该方法极具吸引力,因为催化剂的负载量低,优化的反应条件温和且底物范围广.
DOI:10.1002/chem.201103438

专利信息

专利号:US-9765077-B2
优先权日:2015-05-29
标题:Synthesis of duocarmycin analogues
发明人：STEPHENSON MICHAEL J; HOWELL LESLEY A; SEARCEY MARK
权利人:UNIV OF EAST ANGLIA
摘要:A novel Fmoc protected duocarmycin subunit and utilization as a reagent in solid phase protein synthesis methodology. Also provided is a novel method of solid phase peptide synthesis, and in particular a method for the production of novel intermediates and novel monomeric and extended duocarmycin analogues having amino acid substituents.

专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人：FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

专利号:US-8410130-B2
优先权日:2007-11-07
标题 :Synthesis of 8H-3A-aza-cyclopenta [A ]indenes and 5,10-dihydropyrrolo[1,2-B]isoquinolines derivatives and their use as antitumor therapeutic agents
发明人：SU TSANN-LONG; CHOU TING-CHAO
权利人:SU TSANN-LONG; CHOU TING-CHAO; ACADEMIA SINICA
摘要:The present disclosure relates to a series of bis(hydroxymethyl) and its bis(carbamate) of 8H-3a-azacyclopenta[a]indene-1-yl and 5,10-dihydropyrrolo-[1,2-b]isoquinolines derivatives (Formula I-Formula IV) as DNA di-alkylating agents. The preliminary antitumor studies indicated that compounds disclosed herein could exhibit potent cytotoxicity in vitro and antitumor therapeutic efficacy in human tumor xenografts and could have little or no cross-resistance to either Taxol or Vinblastine. The results demonstrated that compounds disclosed herein possess potent antitumor therapeutic efficacy and are expected to have potential for clinical applications.

专利号:US-11702652-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2009117125-A1
优先权日:2007-11-07
标 题:Synthesis of 8h-3a-aza-cyclopenta[a]indenes and 5,10-dihydropyrrolo[1,2-b]isoquinolines derivatives and their use as antitumor therapeutic agents

专利号:US-2009264300-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries