CAS: 6574-99-8; 3,4-Dichlorobenzonitrile

上下游产品

benzenesulfonamide 3,4-dichlorbenzoic acid m,p-dichloroaniline 3.4-Dichlorbenzaldehyd-phenylhydrazon 3,4-dichlorbenzoic acid 3-chloro-4-morpholin-4-yl-benzonitrile 3-chloro-4-(N,N-dimethylamino)benzonitrile 3,4-dichloro-benzimidic acid ethyl ester hydr°Chloride salt

3,4-二氯苯甲酸置于ammonium Hydroxide,氯化亚砜体系中,化学反应生成 3,4-二氯苯腈
参考文献:Synthesis And Evaluation Of The Anticonvulsant Activity Of A Series Of 2-Amino-1-Phenyl-1-Propanols Derived From The Metabolites Of The Antidepressant Bupropion
标题:Synthesis And Evaluation Of The Anticonvulsant Activity Of A Series Of 2-Amino-1-Phenyl-1-Propanols Derived From The Metabolites Of The Antidepressant Bupropion
摘要:A Series Of 2-Amino-1-Phenyl-1-Propanols That Are Structurally Related To Known Metabolites Of Bupropion,1 (Wellbutrin(R)) Were Synthesized And Evaluated As Potential Anticonvulsants. The (R*,R*)-2-Tert-Butylamino-1-(3-Trifluoromethylphenyl) Propanol 20 Had An Ed(50) Of 16.5 +/-2.8 Mg/kg Ip In Mice In The Maximal Electroshock Screen And Was Chosen For Further Evaluation. Copyright (C) 1996 Elsevier Science Ltd
DOI:10.1016/s0960-894X(96)00577-X

专利信息

专利号:US-4536599-A
优先权日:1978-08-22
标题:Synthesis of amine derivatives
发明人：MASUKO FUJIO; KATSURA TADASHI
权利人:SUMITOMO CHEMICAL CO
摘要:An amine of the formula, ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are each hydrogen, alkyl or the like and n is 1, 2 or 3, including α-phenyl-β-(p-tolyl)-ethylamine, which is useful as an optically resolving agent, an intermediate of medicines and the like, is effectively produced by a novel process comprising hydrolysis of the corresponding nitrile of the formula, ##STR2## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above, followed by alkali-decomposition of the resulting amide of the formula, ##STR3## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above. An amide including the above one is effectively produced by hydrolysis of the corresponding nitrile in the presence of a base and hydrogen peroxide using an organic quaternary ammonium salt and/or a tertiary amine as a catalyst.

专利号:CN-102924329-A
优先权日:2012-11-14
标题:Ammoxidative synthesis of 3,4-dichlorobenzonitrile method

专利号:CN-119015863-B
优先权日:2024-10-29
标 题:A method for recovering and treating ammonia-containing tail gas in the rear section of the synthesis of aromatic nitrile

专利号:EP-0008532-A1
优先权日:1978-08-22
标 题 :Synthesis of amines

专利号:EP-0008532-B1
优先权日:1978-08-22
标 题 :Synthesis of amines

专利号:EP-0040896-A2
优先权日:1978-08-22
标 题 :Synthesis of amides