CAS: 119-26-6; 2,4-Dinitrophenylhydrazine

上下游产品

CAS号97-00-7 1-氯-2,4-二硝基苯 | CAS号610-54-8 2,4-二硝基苯乙醚 | CAS号97-02-9 2,4-二硝基苯胺 | CAS号2486-07-9 Benzene,2,4-din... | CAS号2831-60-9 2-(2,4-二硝基苯氧基)乙醇 | CAS号10242-16-7 (2,4-dinitro-ph... | CAS号67674-33-3 4-(β-Methoxyeth... | CAS号40742-19-6 (+/-)-4-(p-nitr... | CAS号7335-65-1 乙酸肼 | CAS号70-34-8 2,4-二硝基氟苯 | CAS号606-22-4 2,6-二硝基苯胺 | CAS号5267-25-4 hex-5-en-1-ylma... | CAS号1459-62-7 N-(cyclo°Ctylid... | CAS号14714-07-9 N-[(2-ethylcycl... | CAS号14252-11-0 bicyclo[4.2.1]n... | CAS号14086-21-6 Butanal, 2-ethy... | CAS号2121-91-7 2,4-dinitro-N-(... | CAS号19353-30-1 N-(3-methylpent... | CAS号18384-06-0 2-Cyclohexen-1-...

苯肼置于bismuth (III) Nitrate Pentahydrate,Palladium Diacetate体系中,用 2,2,2-三氟乙醇,三氟乙酸 用作溶剂,化学反应 24.0H,以69%的收率获得2,4-二硝基苯肼
参考文献:Pd(oac)2催化芳香胺的硝化反应
标题:Pd(oac)2催化芳香胺的硝化反应
摘要:利用pd(oac)2与bi(no 3)3 .5H 2 O在三氟乙醇(tfe)和三氟乙酸(tfa)中催化的硝化反应,我们开发了一种高效且实用的方法来合成仲二硝基-芳香胺.该产品可用于制备5-胺-N-甲基-苯并咪唑酮,具有偶氮染料的经济优势.该方法还扩展到某些叔芳族胺的硝化反应.
Doi:10.1016/j.Tet.2015.04.013

专利信息

专利号:US-3992413-A
优先权日:1975-07-25
标 题 :Intermediates in the synthesis of prostaglandins
发明人：TAUB DAVID; WENDLER NORMAN L
权利人:MERCK & CO INC
摘要:The invention relates to a new and novel synthesis of prostaglandin E 2 , and it particularly relates to a novel process starting with relatively inexpensive starting materials. The invention further relates to a synthesis which is readily adaptable for large scale processing because of the high yields in the individual reaction steps. n The invention further relates to novel compounds formed as intermediates in the synthesis of prostaglandin E 2 . The invention still further relates to synthetic analogs and known metabolites of prostaglandin E 2 and prostaglandin E 1 , useful as standards in certain biological assays for determining prostaglandin-like activity.

专利号:US-2023183177-A1
优先权日:2020-04-24
标题:Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds
发明人：GRILL BIRGIT; WINKLER MARGIT; SCHWAB HELMUT; STROHMEIER GERNOT; DONSBACH KAI; WALDVOGEL SIEGFRIED R; ARNDT SEBASTIAN; WEIS DOMINIK
权利人:PHARMAZELL GMBH
摘要:The present invention relates to a novel biocatalytic process for the stereoselective preparation of alpha amino amide compounds catalyzed by NHase enzymes. A further aspect of the invention relates to novel NHase enzymes as well as further improved NHase enzyme mutants, nucleic acid molecules encoding these enzymes, recombinant microorganisms suitable for preparing such enzymes and mutants. Another aspect of the invention relates to a chemo-biocatalytic process for the preparation of lactam compounds comprising the new catalytic process for the preparation of alpha amino amide compounds catalyzed by NHase enzymes, as well as the chemical oxidation of the alpha amino amide by applying certain chemical oxidation catalysts suitable for converting the alpha amino amide under retention of its stereochemical configuration to the respective lactam. The novel chemo-biocatalytic process is particularly suited for the synthesis of valuable pharmaceutical compounds, like in particular (S)-Levetiracetam.

专利号:US-4302612-A
优先权日:1976-07-15
标 题:Synthesis of perfluorodialdehydes
发明人：EVANS DAVID H; GREENWALD RICHARD B
权利人:POLAROID CORP
摘要:This invention is concerned with the synthesis of perfluorodialdehydes from the corresponding perfluorodiesters and with intermediates useful in the preparation of the perfluorodialdehydes.

专利号:EP-1397373-B1
优先权日:2001-06-07
标 题 :Improved synthesis of allofuranose
发明人：KOCH TROELS; HANSEN HENRIK FRYDENLUND
权利人:SANTARIS PHARMA AS
摘要:The present invention provides a novel strategy for the synthesis of allofuranose using glucofuranose as starting material in a one-pot reaction. The novel finding is that it is possible to carry out the oxidation of 1,2: 5,6-di-O-isopropylidene- alpha -D-glucofuranose with DMSO/acetic anhydride and a reduction reaction in one pot obtaining high yields of recrystallised and analytical pure 1,2:5,6-di-O-isopropylidene- alpha -D-allofuranose.

专利号:US-6858726-B2
优先权日:2001-06-07
标 题:Synthesis of allofuranose
发明人：KOCH TROELS; HANSEN HENRIK FRYDENLUND
权利人:SANTARIS PHARMA AS
摘要:The present invention provides a novel strategy for the synthesis of allofuranose using glucofuranose as starting material in a one-pot reaction. The novel finding is that it is possible to carry out the oxidation of 1,2:5,6-di-O-isopropylidene-alpha-D-glucofuranose with DMSO/acetic anhydride and a reduction reaction in one pot obtaining high yields of recrystallised and analytical pure 1,2:5,6-di-O-isopropylidene-alpha-D-allofuranose.

专利号:US-6310180-B1
优先权日:1993-06-21
标 题 :Method for synthesis of proteins
发明人：TAM JAMES P
权利人:UNIV VANDERBILT
摘要:A method for peptide synthesis is disclosed that requires neither protecting groups nor activation of the C-α carboxyl groups. The method comprises ligating a first molecule to a second molecule by promoting the orthogonal coupling of the molecules to each other. In an aspect of this method, an acyl-type reaction occurs between the molecules. The method contemplates the joining of molecules of variant size to each other, as well as the coupling of multiple identical molecules. The invention also covers the ligation of unprotected peptide, proteins or nonpeptide segments to prepare therapeutic products and synthetic vaccines with linear, circularized, or branched backbone structures, as well as the site-specific modification of peptides or proteins by lipidation and pegylation.