CAS: 24677-78-9; 2,3-Dihydroxybenzaldehyde

上下游产品

CAS号148-53-8 邻香草醛 | CAS号492-88-6 3-乙氧基水杨醛 | CAS号86-51-1 2,3-二甲氧基苯甲醛 | CAS号67-66-3 氯仿 | CAS号120-80-9 邻苯二酚 | CAS号123-75-1 四氢吡咯 | CAS号340257-73-0 methyl 2-(4-for... | CAS号100-83-4 间羟基苯甲醛 | CAS号66495-88-3 2-甲氧基-3-羟基苯甲醛 | CAS号5768-39-8 1,3-亚甲二氧杂环戊烯-4-羧酸 | CAS号14235-77-9 3-(羟基甲基)邻苯二酚 | CAS号4442-53-9 2,3-二氢-1,4-苯并二烷-5-羧酸 | CAS号18102-31-3 2-Methoxy-3-met... | CAS号182067-51-2 2-Ethoxy-3-hydr... | CAS号274910-19-9 (2,3-二氢苯并[b][1,... | CAS号7797-83-3 1,3-苯并二氧-4-甲醛 | CAS号29477-83-6 水仙环素 | CAS号66495-88-3 2-甲氧基-3-羟基苯甲醛 | CAS号86-51-1 2,3-二甲氧基苯甲醛

2,3-二甲氧基苯甲醛置于三溴化硼体系中,用 二氯甲烷 用作溶剂,化学反应 24.0H,以85%的收率获得2,3-二羟基苯甲醛
参考文献:分子内邻喹啉甲烷/硝基苯乙烯-环加成反应的(+/-)-白屈菜碱和(+/-)-去甲屈菜碱的高立体选择性总合成
标题:分子内邻喹啉甲烷/硝基苯乙烯-环加成反应的(+/-)-白屈菜碱和(+/-)-去甲屈菜碱的高立体选择性总合成
摘要:描述了将2-溴甲基苯乙烯22和氨基甲酸苯并环丁烯基酯28转化为苯并菲啶生物碱(+/-)-鸟苷(1,五步,从28%降低到25%)和到(+/-)-去氯酮碱(2,六步,从28%降低到24%). .关键步骤29 31涉及(e)-喹二甲烷30的高度区域和立体控制的分子内diels-Alder反应.
Doi:10.1002/hlca.19830660415

专利信息

专利号:WO-2021014395-A1
优先权日:2019-07-24
标题:Process for the synthesis of deuterated capsaicin, capsaicinoids and synthetic capsaicin analogs
发明人：ORUGANTI SRINIVAS; AMRUTAPU SRAVANTH KUMAR; SAMPATH MAGESH; SEN SAIKAT
权利人:DR REDDY’S INST OF LIFE SCIENCES
摘要:The present application provides novel processes for the synthesis of deuterated intermediates of capsaicinoids, particularly II, III, IV and V of capsaicinoids, relating to pharmaceutical applications. The invention also provides novel intermediates of compounds of formula IX, XIV, XV, XVI, XVII, XVIII, XX and XXI utilized in the process of making deuterated capsaicin II, III, IV and V.

专利号:US-9315483-B2
优先权日:2007-09-13
标题 :Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof
发明人：JONES ANDREW D; ZELLE ROBERT E; SILVERMAN I ROBERT
权利人:CONCERT PHARMACEUTICALS INC
摘要:The present invention provides a convenient and efficient process for the synthesis of d 2 -benzo[d][1,3]dioxoles.

专利号:US-2009326223-A1
优先权日:2006-07-18
标题 :Synthesis of 2-amino-substituted 4-oxo-4h-chromen-8.yl-trifluoro-methanesulfonic acid esters
发明人：GRIFFIN ROGER JOHN; HARDCASTLE IAN ROBERT; DESAGE-EL MURR MARINE; RODRIGUEZ-ARISTEGUI SONSOLES; GOLDING BERNARD THOMAS
权利人:GRIFFIN ROGER JOHN; HARDCASTLE IAN ROBERT; DESAGE-EL MURR MARINE; RODRIGUEZ-ARISTEGUI SONSOLES; GOLDING BERNARD THOMAS
摘要:A method of synthesising a compound of formula (I): wherein R N1 and R N2 are independently selected from hydrogen, an optionally substituted C 1-7 alkyl group, C 3-20 heterocyclyl group, or C 5-20 aryl group, or may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; from a compound of formula (III): comprising the steps of: (a) removing the allyl group from the compound of formula (III) with appropriate reaction conditions to yield a compound of formula (II): and (b) reacting the compound of formula (II) with a triflating agent to yield a compound of formula (I).

专利号:US-5569786-A
优先权日:1987-01-06
标 题 :Isolation, structural elucidation and synthesis of novel antineoplastic substances denominated 'combretastatins'
发明人：PETTIT GEORGE R; SINGH SHEO B
权利人:UNIV ARIZONA
摘要:New antineoplastic substances have been isolated, structurally elucidated and synthesized having a general structural formula of: (I) or H or OCH3; or R1R2 is -OCH2O-; R3 is H or OH; and R4 is OH or OCH3. These substances have been denominated 'combretastatin A-1, -A-2, -A-3, -B-1, -B-2, -B-3 and -B-4'. preparation containing the substances and methods of treating a host inflicted with a neoplastic growth with the preparation is described.

专利号:US-9382288-B2
优先权日:2010-10-06
标题 :Derivatives of steroid benzylamines, having an antiparasitic antibacterial, antimycotic and/or antiviral action
发明人：BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO
权利人:BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO; UNIV GIESSEN JUSTUS LIEBIG
摘要:The present invention relates to compounds derived from steroids of the general formula (I) n nwherein L represents a linker and R # represents a steroid residue, the use of compounds of the general formula (I) in medicine and for the prophylaxis and/or the treatment of infectious diseases. Furthermore described are pharmaceutical compositions containing at least one compound of the general formula (I). A further aspect of the invention relates to the synthesis of said compounds of the general formula (I).

专利号:WO-2021224280-A1
优先权日:2020-05-05
标题:Synthesis of a sickle cell disease agent and intermediates thereof
发明人：JUDGE THOMAS; SCHROEDER MEL C; KOPEL LUCAS C; EKLOV BRIAN M
权利人:DIPHARMA FRANCIS SRL
摘要:New processes for preparing 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5- yl)pyridin-3-yl)methoxy)benzaldehyde, an agent developed for the treatment of sickle cell disease, and intermediates thereof, are provided herein.