CAS: 3878-41-9; 2-(Benzylthio)Ethan-1-Ol

该化合物是一种含有硫的有机化合物,其特点是存在苯基化合物和硫化氢乙基硫酸混合物,该化学品主要用作有机合成的中间体,特别是在生产特殊化学品和药品方面,其双功能结构包括氢氧基和硫化物混合物,允许多功能反应,允许在交叉反应和聚合物修改中应用.该化合物在极地有机溶剂中表现出中等溶性,便于其在各种合成工艺中使用.在受控制条件下,该化学品稳定,成为在复杂分子框架中选择性地发挥功能的可靠试剂.

结构式图片

上下游产品

oxirane phenylmethanethiol sodium 2-mercaptoethanol benzyl chloride 1-benzylsulfanyl-2-butoxy-ethane 2-benzylsulfonylethyl chloride 1-(benzylthio)-2-chloroethane Phosphoric acid 2-benzylsulfanyl-ethyl ester methyl ester 1,2,2,2-tetrachloro-ethyl ester

合成工艺路线路线简述

    Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于lithium Aluminium Tetrahydride,三氯化铝,乙醚体系中,化学反应生成2-苄硫基乙醇
    参考文献:Reductions With Metal Hydrides. Xiii. Hydrogenolysis Of Hemithioacetals And Hemithioketals With Lithium Aluminum Hydride-Aluminum Chloride
    标题:Reductions With Metal Hydrides. Xiii. Hydrogenolysis Of Hemithioacetals And Hemithioketals With Lithium Aluminum Hydride-Aluminum Chloride
    摘要:
    Doi:10.1021/ja00871A021

    海关参考信息

    专利信息


    专利号:EP-2845860-A1
    优先权日:2013-09-10
    标题 :Synthetic vaccines against Streptococcus pneumoniae
    发明人:SEEBERGER PETER H PROF DR; PEREIRA CLANEY LEBEV DR
    权利人:MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V
    摘要:The present invention relates to the total synthesis of saccharide structures contained in the capsular polysaccharide of Streptococcus pneumoniae type 1, to glycoconjugates containing said saccharide structures obtained by total synthesis and to use of such glycoconjugates and pharmaceutical compositions thereof in the immunization against diseases associated with bacteria containing said saccharide structures in their capsular polysaccharide, and more specifically associated with Streptococcus pneumoniae.

    专利号:US-10328141-B2
    优先权日:2013-07-07
    标题:Synthetic vaccines against Streptococcus pneumoniae type 1
    发明人:SEEBERGER PETER H; PEREIRA CLANEY LEBEV; ANISH CHAKKUMKAL; SCHUMANN BENJAMIN
    权利人:MAX PLANCK GESELLSCHAFT
    摘要:The present invention relates to the total synthesis of saccharide structures contained in the capsular polysaccharide of Streptococcus pneumoniae type 1, to glycoconjugates containing said saccharide structures obtained by total synthesis and to use of such glycoconjugates and pharmaceutical compositions thereof in the immunization against diseases associated with bacteria containing said saccharide structures in their capsular polysaccharide, and more specifically associated with Streptococcus pneumoniae.

    专利号:CN-105492454-B
    优先权日:2013-07-07
    标 题:Synthesis is directed to the vaccine of 1 type streptococcus pneumonia

    专利号:CN-108218785-A
    优先权日:2016-12-13
    标题:A kind of ionic liquid for secondary battery and its synthesis method and application
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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Silica-Promoted Facile Synthesis Of Thioesters And Thioethers: A Highly Efficient, Reusable And Environmentally Safe Solid Support
    作者:Basudeb Basu,Susmita Paul,Ashis K. Nanda
    摘要:An Efficient, Mild And Rapid Procedure For The Acylation And Alkylation Of Aromatic And Aliphatic Thiols Mediated On A Silica Gel Surface At Room Temperature Is Described. The Protocol Allows The Protection Of Thiols Under Neutral Heterogeneous Conditions Without Requiring Any Bases Or Lewis Acids, And The Silica Gel Used As The Promoter Can Be Recycled For Several Runs Without Any Loss Of Activity.

    合成参考文献


    摘要:Witt, D., Science of Synthesis Knowledge Updates, (2011) 3, 244.
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