CAS: 522-51-0; 1,1'-(Decane-1,10-Diyl)Bis(4-Amino-2-Methylquinolin-1-Ium) Chloride

上下游产品

4-chloro-2-methylquinoline

专利信息

专利号:US-6144897-A
优先权日:1995-06-09
标 题 :Control method for processes of synthesis of chemical products
发明人：SELLIERS JACQUES DE
权利人:SOLVAY
摘要:PCT No. PCT/EP96/02408 Sec. 371 Date Dec. 9, 1997 Sec. 102(e) Date Dec. 9, 1997 PCT Filed Jun. 1, 1996 PCT Pub. No. WO96/41822 PCT Pub. Date Dec. 27, 1996A control method for a process of synthesis of at least one chemical product in an equipment comprising at least one reactor (R) which is assimilated to a mixed reactor, in which manipulated variables (GC) allow to act on the course of the process in order to make one or more variables related to the properties of the product and/or to the running of the process, which are called controlled variables (GR).

专利号:US-10022366-B2
优先权日:2013-04-23
标 题:Extending and maintaining micropore viability of microneedle treated skin with lipid biosynthesis inhibitors for sustained drug delivery
发明人：STINCHCOMB AUDRA L; GHOSH PRIYANKA
权利人:STINCHCOMB AUDRA L; GHOSH PRIYANKA; UNIV MARYLAND; UNIV KENTUCKY RES FOUND
摘要:Microneedles and their use as a physical skin permeation enhancement technique facilitate drug delivery across the skin in therapeutically relevant concentrations. Micropores created in the skin by MNs reseal because of normal healing processes of the skin, thus limiting the duration of the drug delivery window. Pore lifetime enhancement strategies can increase effectiveness of MNs as a drug delivery mechanism by prolonging the delivery window. Fluvastatin (FLU) was used to enhance pore lifetime by inhibiting the synthesis of cholesterol, a major component of the stratum corneum lipids. The skin recovered within a 30-45-min time period following the removal of occlusion, and there was no significant irritation observed due to the treatment compared to the control sites. Thus, it can be concluded that localized skin treatment with FLU can be used to extend micropore lifetime and deliver drugs for up to 7 days across MN-treated skin.

专利号:US-7453011-B2
优先权日:2001-12-07
标题:Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
发明人：CLIFFORD LINDA; VALASINAS ALDONIA L; BLOKHIN ANDREI V; SARKAR APARAJITA; BASU HIRAK S; REDDY VENODHAR K; MARTON LAURENCE J; WANG YU
权利人:PROGEN PHARMACEUTICALS INC
摘要:Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.

专利号:CN-106458847-A
优先权日:2014-05-29
标 题:Synthesis of Novel Diamine and Its Liquid Crystal Alignment Agent

专利号:JP-2019501915-A
优先权日:2015-12-30
标 题 :Selective synthesis of cationic lipids

专利号:AU-704563-B2
优先权日:1995-06-09
标 题:Control method for processes of synthesis of chemical products