CAS: 6373-50-8; 4-Cyclohexylaniline

该化合物是替代的阴离子衍生物,具有附于苯环的环己基组,其位置在准位置上,该化合物通常用作有机合成的中间体,特别是在生产药品,农用化学品和特殊化学品方面,其环己基替代成分可增强...

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CAS号5458-48-0 4-环己基-1-硝基苯 | CAS号3282-99-3 1,1-二(4-氨基苯基)环己烷 | CAS号1747-75-7 4-(1-环己烯基)苯胺 | CAS号827-52-1 环己基苯 | CAS号542-18-7 氯代环己烷 | CAS号105908-26-7 1-cyclohex-3-en... | CAS号100-13-0 4-硝基苯乙烯 | CAS号108-93-0 环己醇 | CAS号74067-99-5 ossima del 4-ci... | CAS号212055-50-0 2-chloro-N-(4-c... | CAS号191722-72-2 1-环己基-4-异氰酰基苯 | CAS号29030-57-7 Acetamide,N-(4-... | CAS号636-98-6 4-硝基碘苯 | CAS号25109-28-8 1-溴-4-环己基苯 | CAS号126062-51-9 4-n-己基苯肼盐酸盐 | CAS号1131-60-8 4-环己基苯酚 | CAS号175205-17-1 N-(4-环己基苯基)硫脲 | CAS号70714-75-9 1,4-Bis(p-cyclo... | CAS号71576-66-4 N-(4-cyclohexyl...

合成工艺路线路线简述

    氯代环己烷置于盐酸,三氯化铝,硝酸,乙酸酐,溶剂黄146,Tin(Ll) Chloride体系中,化学反应生成 4-环己苯胺
    参考文献:Neunhoeffer,Journal Fur Praktische Chemie (Leipzig 1954),1932,Vol. <2> 133,P. 95,105
    标题:Neunhoeffer,Journal Fur Praktische Chemie (Leipzig 1954),1932,Vol. <2> 133,P. 95,105

    海关参考信息

    专利信息


    专利号:WO-0053313-A2
    优先权日:1999-03-09
    标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

    专利号:US-5968736-A
    优先权日:1992-10-01
    标 题 :Methods for recording the reaction history of a solid support
    发明人:STILL W CLARK; WIGLER MICHAEL H; OHLMEYER MICHAEL H J; DILLARD LAWRENCE W; READER JOHN C
    权利人:COLD SPRING HARBOR LAB; UNIV COLUMBIA
    摘要:Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produced in the multi-stage synthesis, such as oligomers and synthetic non-repetitive organic molecules. Conveniently, nested families of compounds can be employed as identifiers, where number and/or position of a substituent define the choice. Alternatively, detectable functionalities may be employed, such as radioisotopes, fluorescers, halogens, and the like, where presence and ratios of two different groups can be used to define stage or choice. Particularly, pluralities of identifiers may be used to provide a binary or higher code, so as to define a plurality of choices with only a few detachable tags. The particles may be screened for a characteristic of interest, particularly binding affinity, where the products may be detached from the particle or retained on the particle. The reaction history of the particles which are positive for the characteristic can be determined by the release of the tags and analysis to define the reaction history of the particle.

    专利号:BR-PI0711208-A2
    优先权日:2006-05-19
    标 题 :compounds, intermediates for the synthesis of compounds, process, pharmaceutical composition, use of a compound and uses

    专利号:US-6503759-B1
    优先权日:1992-10-01
    标题 :Complex combinatorial chemical libraries encoded with tags
    发明人:STILL W CLARK; OHLMEYER MICHAEL H J; DILLARD LAWRENCE W; READER JOHN C; WIGLER MICHAEL H
    权利人:UNIV COLUMBIA; COLD SPRING HARBOR LAB
    摘要:Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produced in the multi-stage synthesis, such as oligomers and synthetic non-repetitive organic molecules. Conveniently, nested families of compounds can be employed as identifiers, where number and/or position of a substituent define the choice. Alternatively, detectable functionalities may be employed, such as radioisotopes, fluorescers, halogens, and the like, where presence and ratios of two different groups can be used to define stage or choice. Particularly, pluralities of identifiers may be used to provide a binary or higher code, so as to define a plurality of choices with only a few detachable tags. The particles may be screened for a characteristic of interest, particularly binding affinity, where the products may be detached from the particle or retained on the particle. The reaction history of the particles which are positive for the characteristic can be determined by the release of the tags and analysis to define the reaction history of the particle.

    专利号:US-5721099-A
    优先权日:1992-10-01
    标 题 :Complex combinatorial chemical libraries encoded with tags
    发明人:STILL W CLARK; WIGLER MICHAEL H; OHLMEYER MICHAEL H J; DILLARD LAWRENCE W; READER JOHN C
    权利人:UNIV COLUMBIA; COLD SPRING HARBOR LAB
    摘要:Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produced in the multi-stage synthesis, such as oligomers and synthetic non-repetitive organic molecules. Conveniently, nested families of compounds can be employed as identifiers, where number and/or position of a substituent define the choice. Alternatively, detectable functionalities may be employed, such as radioisotopes, fluorescers, halogens, and the like, where presence and ratios of two different groups can be used to define stage or choice. Particularly, pluralities of identifiers may be used to provide a binary or higher code, so as to define a plurality of choices with only a few detachable tags. The particles may be screened for a characteristic of interest, particularly binding affinity, where the products may be detached from the particle or retained on the particle. The reaction history of the particles which are positive for the characteristic can be determined by the release of the tags and analysis to define the reaction history of the particle.

    专利号:US-6001579-A
    优先权日:1993-10-01
    标 题 :Supports and combinatorial chemical libraries thereof encoded by non-sequencable tags
    发明人:STILL W CLARK; WIGLER MICHAEL H; OHLMEYER MICHAEL H J; DILLARD LAWRENCE W; READER JOHN C
    权利人:UNIV COLUMBIA; COLD SPRING HARBOR LAB
    摘要:Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produced in the multi-stage synthesis, such as oligomers and synthetic non-repetitive organic molecules. Conveniently, nested families of compounds can be employed as identifiers, where number and/or position of a substituent define the choice. Alternatively, detectable functionalities may be employed, such as radioisotopes, fluorescers, halogens, and the like, where presence and ratios of two different groups can be used to define stage or choice. Particularly, pluralities of identifiers may be used to provide a binary or higher code, so as to define a plurality of choices with only a few detachable tags. The particles may be screened for a characteristic of interest, particularly binding affinity, where the products may be detached from the particle or retained on the particle. The reaction history of the particles which are positive for the characteristic can be determined by the release of the tags and analysis to define the reaction history of the particle.
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    合成参考文献


    摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 180.
    摘要:Sharma, U.; Kumar, R.; Gupta, S. S.; Chandra, D., Science of Synthesis Knowledge Updates, (2022) 2, 260.
    摘要:Y.S. Shabarov, T.P. Surikova and R.Y. Levina. Zh. Org. Khim. 4, 1175 (1968).
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