CAS: 74070-46-5; 2-Chloro-6-Nitro-3-Phenoxyaniline

该化合物是一种选择性除草剂,主要用于控制各种作物中的宽叶草和某些草,属于二苯醚化学类,其特点是能够通过干扰光合作用过程抑制目标植物的生长.亚克隆芬通常根据具体应用和作物类型,在出现前或出现后施用.该物质在土壤中具有中等持久性,可因温度和湿度等环境条件而有所差异.一般认为它对哺乳动物的毒性较低,但与许多杀草剂一样,它会给水生生物和非目标植物物种带来危险.亚克隆芬往往被配制成乳油或颗粒,使其能用于农业用途.适当处理和应用对于最大限度地减少环境影响和确保安全至关重要.与任何化学物质一样,在农业实践中使用亚克隆芬时,遵守管制准则和安全议定书至关重要.

结构式图片

物理性质

欧盟法规

统一分类与标签ECHA物质欧盟农药活性物质ECHA物质化妆品禁用物质清单C&L通报工作场所安全标识要求食品接触材料-禁用CMR物质欧盟《水框架指令》附件XREACH预注册废弃物危险特性清单

合成工艺路线路线简述

    2,3-二氯-6-硝基苯胺置于sodium Phenoxide体系中,用 氯仿,水,异丙醇,乙腈 作为反应溶剂,化学反应生成 苯草醚
    参考文献:2-Chloro-3-(Phenoxy Or Phenylthio)-6-6-Nitro-Anilines
    标题:2-Chloro-3-(Phenoxy Or Phenylthio)-6-6-Nitro-Anilines
    摘要:这项发明涉及具有以下结构的2-氯-6-硝基苯胺化合物##str1##其中a代表氢,具有1至6个碳原子的直链或支链烷基基团,具有3至6个碳原子的环烷基基团,具有2至6个碳原子的氯代或羟基代烷基基团,或烯丙基或三氟乙酰基;b代表氢或甲基,乙基,正丙基或异丙基基团,或a和b一起代表由氧,.Dbd.Nh或.Dbd.Nch.Sub.3可选中断的最多5个成员的烷基基团,或.Group.Dbd.Ch-N(Ch.Sub.3).Sub.2;r代表氢,氟,氯或溴或三氟甲基,甲基或甲氧基基团;x代表氧或硫,并且包含这些化合物作为活性成分的新型除草剂组合物.

    海关参考信息

    专利信息


    专利号:WO-2024256370-A1
    优先权日:2023-06-13
    标 题 :Synthesis of glufosinate using an amidase-based process
    发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

    专利号:US-2025120400-A1
    优先权日:2021-12-10
    标题:Synthesis of glufosinate using a hydantoinase-based process
    发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

    专利号:US-11919928-B2
    优先权日:2016-03-16
    标题 :Method for producing dihydrotentoxin
    发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
    权利人:KUMIAI CHEMICAL INDUSTRY CO
    摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

    专利号:US-2021386068-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

    专利号:US-2019031650-A1
    优先权日:2016-01-29
    标 题 :Dna alkylation and cross-linking agents as compounds and payloads for targeted therapies
    发明人:HERZON SETH; HEALY ALAN; CRAWFORD JASON; VIZCAINO MARIA; NIKOLAYEVSKIY HERMAN
    权利人:UNIV YALE
    摘要:The present invention is directed to compounds related to precolibactin pharmaceutical compositions based upon these compounds and methods of synthesis which are employed to provide intermediates and final compounds, which are principally alkylating agents and anticancer compounds. The chemical synthetic approach disclosed facilitates the synthesis of numerous precolibactin analogs which can be used in the treatment of cancer.

    专利号:US-2021352899-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.
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    主要参考文献

    [参考文献]: Laura Sánchez-Hernández, Et Al. Residues Of Neonicotinoids And Their Metabolites In Honey And Pollen From Sunflower And Maize Seed Dressing Crops. J Chromatogr A. 2016 Jan 8:1428:220-7.
    [参考文献]: M Dhouib, Et Al. Rapid Method For Analysis Of Chloroacetanilide And Chloronitrophenoxyaniline Herbicides By Gas Chromatography. Cent Eur J Public Health. 1996:4 Suppl:51-2.

    合成参考文献


    摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664
    参考文献:10.1007/s00216-006-0693-x
    摘要:Perreau F, Einhorn J. Determination of frequently detected herbicides in water by solid-phase microextraction and gas chromatography coupled to ion-trap tandem mass spectrometry. Analytical and Bioanalytical Chemistry. 2006 Aug 26;386(5):1449–56. doi: 10.1007/s00216-006-0693-x.
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