CAS: 109-81-9; N1-Methylethane-1,2-Diamine

该化合物是一种多用途的脂性二胺,其分子式为C3H10N2.它具有初级和二级的矿物质功能,使其成为有机合成中有价值的中间体,特别是用于生产发泡剂,药品和农用化学品,其双功能性质允许在凝聚和电温反应中选择性反应.该化合物在水和极地有机溶剂中表现出良好的溶解性,便于其在水体和非水体系统中使用.N-甲基乙基二乙胺还被用作聚合化学的交叉剂或单体修饰剂,因其腐蚀性和湿性特性需要适当处理.

结构式图片

相似化合物

18807-71-1 4152-09-4 57260-73-8

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号870-24-6 2-氯乙胺盐酸盐 | CAS号67-56-1 甲醇 | CAS号107-15-3 乙二胺 | CAS号2576-47-8 2-溴乙胺氢溴酸盐 | CAS号74-89-5 氨基甲烷 | CAS号6274-53-9 Acetamide,N-[2-... | CAS号74-88-4 碘甲烷 | CAS号5616-32-0 甲氨基乙腈 | CAS号87768-63-6 (4-nitrophenyl)... | CAS号74-89-5 氨基甲烷 | CAS号34770-60-0 1-甲基-3-氧代哌嗪 | CAS号19853-99-7 1,4-bis(2-methy... | CAS号181761-60-4 甲基(2-(2,2,2-三氟乙... | CAS号2898-12-6 美达西泮 | CAS号141089-27-2 Pyrazine, 1,2,5... | CAS号107-15-3 乙二胺 | CAS号694-32-6 1-甲基-2-咪唑啉酮 | CAS号101998-53-2 1-(1-methylimid...

合成工艺路线路线简述

  • 合成目标产物 N-Methylethylenediamine 主要起始原料 2-Chloroethylamine Hydrochloride
  • (文献来源)合成步骤主要原料 2-Chloroethylamine Hydrochloride
Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于乙醚,镍体系中,化学反应生成N-甲基乙二胺
参考文献:The Synthesis And Reactions Of Certain Nitrogen Ring Compounds Over Nickel
标题:The Synthesis And Reactions Of Certain Nitrogen Ring Compounds Over Nickel
摘要:
Doi:10.1021/ja01337A046

海关参考信息

专利信息


专利号:US-6184168-B1
优先权日:1997-09-22
标题:Synthesis of 1,4-trans-polybutadiene using a lanthanide organic acid salt catalyst
发明人:LYNCH THOMAS J
权利人:BRIDGESTONE CORP
摘要:The invention provides a catalyst composition, comprising: (a) an organolithium compound; and, (b) an organic acid salt of lanthanide series element; wherein: (1) only components (a) and (b) are required to promote the synthesis of 1,4-trans-polybutadiene; (2) the ratio of component (a) to component (b) is selected to maximize formation of the trans structure of said 1,4-trans-polybutadiene; and, (3) components (a) and (b) are selected for enabling further diblock synthesis. The invention further contemplates a process for using the catalyst to synthesize 1,4-trans-polybutadiene and other polymers and copolymers having trans configuration in the conjugated diene monomer contributed units.

专利号:WO-9517903-A1
优先权日:1993-12-28
标 题:Modular design and synthesis of oxazolone-derived molecules
发明人:HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG
权利人:ARQULE PARTNERS L P; HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG
摘要:The design and synthesis of novel oxazolone-derived molecular modules and the use of the modules in the construction of new molecules and fabricated materials is disclosed. The new molecules and fabricated materials are molecular recognition agents useful in the design and synthesis of drugs, and have applications in separations and materials science.

专利号:US-8735586-B2
优先权日:2007-06-26
标 题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR
权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR; SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:US-9440928-B2
优先权日:2011-07-20
标题 :Process for the synthesis of N-substituted cyclic alkylene ureas
发明人:GUPTA RAM; KOBYLANSKA IRINA; TREASURER URVEE; FLOOD LAWRENCE
权利人:GUPTA RAM; KOBYLANSKA IRINA; TREASURER URVEE; FLOOD LAWRENCE; ALLNEX IP S AR L
摘要:The invention relates to a process for the synthesis of N-substituted cyclic alkylene ureas by reacting a multifunctional aliphatic amine A having at least two amino groups which may be primary or secondary, at least one of which is a primary amino group, —NH 2 , and at least one of which is a secondary amino group, >NH, the other hydrogen group whereof having been substituted by a hydrocarbyl group which in turn may be substituted by a hydroxyl group, or an amino group, or a carboxyl group, or a ketone carbonyl group, or a hydrazide or hydrazone group, or a mercaptan group, and at least one further functional group selected from the group consisting of primary or secondary amino groups and hydroxyl groups, and an aliphatic organic carbonate component C selected from the group consisting of dialkyl carbonates CD and of alkylene carbonates CA.

专利号:EP-2173747-B1
优先权日:2007-06-26
标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS
权利人:SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:US-6987186-B2
优先权日:2003-01-28
标 题 :Synthesis of small particle size quinacridone of beta crystal phase
发明人:COLE DAMIEN THURBER; JEGANATHAN SURULIAPPA GOWDER; HE YINGXIA
权利人:CIBA SC HOLDING AG
摘要:The present invention relates to a process for the synthesis of beta-quinacridone by oxidation in the presence of selected additives that promote the formation of the desired crystal phase and particle size.
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主要参考文献

[参考文献]: Neil Vasdev, Et Al. Rationally Designed Pka Inhibitors For Positron Emission Tomography: Synthesis And Cerebral Biodistribution Of N-(2-(4-Bromocinnamylamino)Ethyl)-N-[参考文献]: Nidhi Shrivastav, Et Al. A Chemical Genetics Analysis Of The Roles Of Bypass Polymerase Dinb And Dna Repair Protein Alkb In Processing N2-Alkylguanine Lesions In Vivo. Plos One. 2014 Apr 14;9(4):E94716.

合成参考文献


摘要:Chand, K.; Umesh; Dorairaj, D. P.; Hsu, S. C. N., Science of Synthesis Knowledge Updates, (2021) 2, 288.
摘要:Ye, Z.-S., Science of Synthesis Knowledge Updates, (2021) 2, 354.
摘要:Ye, Z.-S., Science of Synthesis Knowledge Updates, (2021) 2, 359.
摘要:Ye, Z.-S., Science of Synthesis Knowledge Updates, (2021) 2, 364.
摘要:Bartsch, S.; Vogel, A., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 2, 298.
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