CAS: 13630-19-8; 1-Methyl-2-(Trifluoromethyl)Benzene

相似化合物

433-95-4 312-95-8 41818-96-6

上下游产品

1-methyl-2-trichloromethyl-benzene α-picoline Bromotrifluoromethane ortho-methylphenyl iodide 1-methyl-2-(prop-1-en-2-yl)benzene 1-tert-butyl-2-methyl-benzene

(Ruphos)Pd(C2F5)(Ph) 以 氘代苯 用作溶剂,化学反应 12.0H,以65%的收率获得邻甲基三氟甲苯
参考文献:三氟乙酸酯为cf 3源的钯催化脱羰三氟甲基化的催化循环
标题:三氟乙酸酯为cf 3源的钯催化脱羰三氟甲基化的催化循环
摘要:本文证明了使用三氟乙酸酯作为cf 3源的pd催化脱羰三氟甲基化的催化循环.拟议的循环包括四个基本步骤:(1)将三氟乙酸酯氧化加成到pd 0中;(2)从所得的三氟酰基pd Ii络合物中脱co ;(3)芳基锌的金属转移成pd Ii;和(4 )芳基-Cf 3键形成的还原消除.使用ruphos作为支持配体可以使这些步骤中的每一个都在温和的条件下(<100oc)进行.这些研究为使用廉价的三氟乙酸衍生的cf 3开发催化芳烃三氟甲基化和全氟烷基化反应奠定了基础. 资料来源.
Doi:10.1021/om500398Z

专利信息

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2002103381-A1
优先权日:2000-11-30
标 题 :Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

专利号:US-11999757-B2
优先权日:2017-11-01
标 题:Synthesis of boronate ester derivatives and uses thereof
发明人：BOYER SERGE HENRI; HECKER SCOTT J; VERZIJL GERARDUS K M; HERMSEN PETRUS J
权利人:MELINTA SUBSIDIARY CORP
摘要:Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.

专利号:US-2006167289-A1
优先权日:2003-12-05
标题 :Practical, cost-effective synthesis of ubiquinones
发明人：LIPSHUTZ BRUCE H; BERL VOLKER; SCHEIN KARIN; WETTERICH FRANK
权利人:ZYMES LLC
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:US-10669292-B2
优先权日:2014-05-05
标 题 :Synthesis of boronate salts and uses thereof
发明人：HECKER SCOTT; BOYER SERGE
权利人:REMPEX PHARMACEUTICALS INC
摘要:Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.

专利号:US-2005014954-A1
优先权日:2001-11-22
标 题:Pyrrole synthesis
发明人：OHRLEIN REINHOLD; BAISCH GABRIELE
摘要:The invention relates to a novel process for the preparation of N-substituted pyrroles, especially of formula (V), wherein the radicals are as defined in the description, by intermolecular aza-Wittig reaction starting from organic azides and 1,4-dioxo compounds. The invention relates also to novel iminophosphorane intermediates for this synthesis. The resulting pyrroles are useful, for example, in the organic synthesis of pharmaceuticals or other active substances and chemicals.