相似化合物
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2-(3-(benzyloxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 3-(benzyloxy)phenyl bromide tri-n-propyl borate Triisopropyl borate 3'-benzyloxy-5-nitro-biphenyl-2-carboxylic acid benzyl ester 2-[3-(3-benzyloxy-phenoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 5-(3-benzyloxy-phenyl)-2,2-dimethyl-benzo[1,3]dioxin-4-one ethyl 1-{[3'-(benzyloxy)biphenyl-3-yl]oxy}cyclobutanecarboxylate 合成工艺路线路线简述
- 合成目标产物 3-Benzyloxybenzeneboronic Acid 主要起始原料 3-Benzyloxybromobenzene
- (文献来源)合成步骤主要原料 3-Benzyloxybromobenzene
3-苄氧基溴苯置于正丁基锂,硼酸三甲酯,盐酸,水体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应 1.0H,以66%的收率获得3-苄氧基苯硼酸
参考文献:The Dramatic Influence Of The Location Of Bend And Of Lateral Fluoro Substitution On The Mesomorphic Properties Of Angular Chiral Esters Based On A 1,3-Disubstituted Benzene Ring
标题:The Dramatic Influence Of The Location Of Bend And Of Lateral Fluoro Substitution On The Mesomorphic Properties Of Angular Chiral Esters Based On A 1,3-Disubstituted Benzene Ring
摘要:本文详细描述了一系列基于1,3-二取代苯单元的3环和4环手性酯的合成及其介态特性.这些材料都偏离了液晶的常规线性分子结构,因此具有角度特性.其中一些材料的弯曲位于分子末端,链条偏离正常线性排列,因此可以准确描述为"曲棍球棒"分子结构.其他材料则具有真正的弯曲核结构,弯曲指向分子的中心,因此最好称为"回旋镖"形状.在所有情况下,各种角度材料之间以及与其线性类似物之间的介相形态和转变温度进行了有趣的比较.特别是,在新型角态材料中,侧向氟 Substituion 对转变温度的影响与已知线性类似物中的结果有显著不同.该研究工作是一个更大正在进行的研究项目的一部分,旨在探讨角液晶的介态和手性依赖特性.研究表明,当弯曲靠近分子的中心时,母体化合物中不可能出现介态.然而,这类化合物的侧向氟替代促进了液晶相的生成.当分子的弯曲是由于核心末端的末端单元引起时,则意外地得到了高清晰度点,同时这种材料显示出高倾斜角的潜力,以及强烈的螺旋介相倾向.对这些后者例子的侧向氟替代一致性地导致了明显更高的清晰度点,这与已知线性分子结构液晶中报告的行为形成了鲜明对比.
Doi:10.1039/b923267B
海关参考信息
- 2902300000-甲苯
2905110000-甲醇
2906210000-苄醇
2908199090-其他酚的卤化衍生物 - 💡 提示:海关信息按照顺序优先匹配,如需确认的海关信息,请参考相关资料。
- 详情请参考:📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9914695-B2
优先权日:2015-07-10
标题:Two-step process for preparing 3-substituted phenylalkylamines
发明人:Teramura Doug; LIAO SUBO
权利人:MALLINCKRODT LLC
摘要:Processes for preparing 3-substituted phenylalkylamines comprising reacting a phenyl boronic compound with an α-β unsaturated carbonyl-containing compound via an asymmetric 1,4-addition reaction, followed by reductive alkylation. The processes may be useful in the synthesis of tapentadol.
专利号:US-2009227575-A1
优先权日:2008-03-04
标 题 :7H-PYRROLO[2,3-H]QUINAZOLINE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESIS
发明人:VENKATESAN ARANAPAKAM MUDUMBAI; CHEN ZECHENG; DOS SANTOS OSVALDO; BROOIJMANS NATASJA; GOPALSAMY ARIAMALA
权利人:WYETH CORP
摘要:A 7H-pyrrolo[2,3-h]quinazoline compound of the formula I n n n n n n n n n n wherein Ar, R 1 , R 2 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , and n are as defined in the specification, and methods for making same.
专利号:US-7737166-B2
优先权日:2005-08-17
标 题:Antifungal bicyclic hetero ring compounds
发明人:KAWAKAMI KATSUHIRO; KANAI KAZUO; HORIUCHI TAKAO; TAKESHITA HIROSHI; KOBAYASHI SYOZO; SUGIMOTO YUICHI; ACHIWA ISSEI; KUROYANAGI JUNICHI
权利人:DAIICHI SANKYO CO LTD
摘要:A 1,6-β-glucan synthetase inhibitor is provided, having potent growth inhibition and having excellent safety. A compound is provided, capable of expressing in a wide spectral range and specifically or selectively, an antifungal effect based on its functional mechanism of 1,6-β-glucan synthesis inhibition. Also provided is a drug, a salt or hydrate thereof, especially an antifungal that contains the compound. Concretely, provided is a compound of the following formula (I), its salt or hydrate, and a drug or antifungal containing, as the active ingredient, the compound, its salt or hydrate: