CAS: 159451-66-8; N-Boc-2-Amino-5-Bromopyridine

相似化合物

84539-30-0 227939-01-7 209959-28-4

上下游产品

5-bromo-2-pyridylamine tert-butyl dicarbonatedi-tert-butyl dicarbonate imidodicarbonic acid (2-(4-bromo-2-pyridinyl)-1,3-bis(1,1-dimethylethyl))ester 2-(tert-butyloxycarbonyl)-aminopyridine-5-carboxaldehyde 2-(N-tert-butoxycarbonylamino)-5-phenylpyridine 2-(tert-butoxycarbonyl)amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (6-[[(tert-butoxy)carbonyl]amino]pyridin-3-yl)boronic acid

二碳酸二叔丁酯置于sodium Hexamethyldisilazane,盐酸体系中,用 四氢呋喃,水 用作溶剂,化学反应 0.58H,以85%的收率获得2-(Boc-氨基)-5-溴吡啶
参考文献:Bicyclic Heterocycles As Cannabinoid Receptor Modulators
标题:Bicyclic Heterocycles As Cannabinoid Receptor Modulators
摘要:本申请描述了符合i式的化合物,包括至少一种符合i式的化合物和可选地一种或多种额外治疗剂的药物组合物,以及使用符合i式的化合物进行治疗的方法,包括单独使用和与一种或多种额外治疗剂结合使用.这些化合物具有一般的i式:包括所有的前药,药用盐和立体异构体,其中r1,R2,R3,R3A,R4,A,B,N,Y和z在此处描述.

专利信息

专利号:US-2010286211-A1
优先权日:2004-10-08
标题:Oxazolidinone derivatives as antimicrobials
发明人：DAS BISWAJIT; AHMED SHAHADAL; YADAV AJAY SINGH; GHOSH SOMA; GUJRATI ARTI; SHARMA PANKAJ; RATTAN ASHOK
权利人:DAS BISWAJIT; AHMED SHAHADAL; YADAV AJAY SINGH; GHOSH SOMA; GUJRATI ARTI; SHARMA PANKAJ; RATTAN ASHOK
摘要:The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria, for example, multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms, for example, Bacterioides spp. and Clostridia spp. species, and acid fast organisms, for example, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

专利号:US-9708336-B2
优先权日:2014-01-22
标题 :Metallo-beta-lactamase inhibitors
发明人：MANDAL MIHIR; TANG HAIFENG; XIAO LI; SU JING; LI GUOQING; YANG SHU-WEI; PAN WEIDONG; TANG HAIQUN; DEJESUS REYNALDA; HICKS JACQUELINE; LOMBARDO MATTHEW; CHU HONG; HAGMANN WILLIAM; PASTERNAK ALEX; GU XIN; JIANG JINLONG; DONG SHUZHI; DING FA-XIANG; LONDON CLARE; BISWAS DIPSHIKHA; YOUNG KATHERINE; HUNTER DAVID N; ZHAO ZHIQIANG; YANG DEXI
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.

专利号:WO-2023168108-A2
优先权日:2022-03-04
标 题 :Synthesis of sulfur(vi) compounds and reagents for same

专利号:CN-111170991-B
优先权日:2014-07-11
标题 :Antiproliferative compounds and methods of synthesis thereof

专利号:CN-111170991-A
优先权日:2014-07-11
标 题:Antiproliferative compounds and methods of synthesis thereof