专利号:US-6482950-B1 优先权日:1991-05-06 标 题 :Squarylium compounds, and processes and intermediates for the synthesis of these compounds 发明人:GARCIA PAULINA P; LEE JOHN W; MARSHALL JOHN L; MCGOWAN DONALD A; PUTTICK ANTHONY J; SPENCER THOMAS K; STROUD STEPHEN G; TELFER STEPHEN J; ZURAW MICHAEL J 权利人:POLAROID CORP 摘要:Squarylium compounds of the formula: n wherein Q 1 and Q 2 are each independently a pyrylium, thiopyrylium, selenopyrylium, benzpyrylium, benzthiopyrylium or benzselenopyrylium nucleus, and R 1 and R 2 are each independently an aliphatic or cycloaliphatic group, can be prepared by reacting a squaric acid derivative of the formula: n with a compound of the formula Q 2 CH 2 R 2 in the presence of a base. The derivatives of Formula II may be prepared by condensing a 2,3,4,4-tetrahalocyclobut-2-en-1-one with a compound of the formula Q 1 CH 2 R 1 in the presence of a base to produce a compound of the formula: n wherein Q 1 and R 1 are as defined above, and X represents chlorine or bromine, and hydrolyzing the compound of Formula III. Alternatively, the derivatives of Formula II may be prepared by reacting a diester, monoacid chloride monoester or diacid chloride of squaric acid with a compound of the formula Q 1 CH 2 R 1 in the presence of a base, followed by hydrolysis of the resultant monoacid chloride or monoester derivative of the compound of Formula II to the parent compound.
专利号:WO-0069864-A1 优先权日:1999-05-19 标 题 :An improved synthesis of tetrakis (dihydro carbylamino) phosphonium halides 发明人:FLETCHER MICHELLE O; DEVROU PHILIP R; BALHOFF JOHN F; ATKINSON BRIAN 权利人:ALBEMARLE CORP 摘要:An improved, commercially viable process for synthesizing tetrakis(dihydrocarbylamino)phosphonium halides in the absence of oxigen is described. When reacting a tris(dihydrocarbylamino)phosphinimine with a halohydrocarbon and an aqueous solution of a source of hydroxide ion to form a tetrakis(dihydrocarbylamino)phosphonium halide, a combination of increased pressure and liquid organic medium is used. The advantages gained by operating in this fashion include shorter reaction times and the need for only about stoichiometric or slightly more than stoichiometric amounts of halohydrocarbon and source of hydroxide ion.
专利号:US-2010069687-A1 优先权日:2006-09-06 标题:Process for synthesis of polyalphaolefin and removal of residual catalyst components 发明人:KOSOVER VILEN; FABIAN JESUS R; KNOWLES DANIEL C; COHN MITCHEL; THURING WERNER A 权利人:CHEMTURA CORP 摘要:A process for reducing the level of residual catalyst comprising one or more 1-halo-2-methylpropanes and a Group 13 metal catalyst from a crude polyolefins product, the process comprising contacting the crude organic product with a solid adsorbent in an adsorbent system. Also provided is a co-catalyst system for polymerizing alpha olefins.
专利号:US-10335382-B2 优先权日:2013-06-14 标 题:Use of hydrogen sulfide synthesis inhibitors for cancer therapy 发明人:HELLMICH MARK; ZHOU JIA; SZABO CSABA 权利人:HELLMICH MARK; ZHOU JIA; SZABO CSABA; UNIV TEXAS 摘要:In certain aspects the methods comprise administering an inhibitor of hydrogen sulfide biosynthesis, a cystathionine-β-synthase (CBS) inhibitor, or a hydrogen sulfide neutralizing agent to a patient having a cancer associated with elevated production of hydrogen sulfide.
专利号:WO-9742158-A1 优先权日:1996-05-03 标题 :Synthesis of a substituted cyclopentadiene compound
专利号:WO-2011046759-A1 优先权日:2009-10-12 标 题 :Process for synthesis of polyalphaolefin
[参考文献]: Wei Huang, Et Al. Dynamics Of Glass-Forming Liquids. X. Dielectric Relaxation Of 3-Bromopentane As Molecular Probes In 3-Methylpentane. J Chem Phys. 2005 Oct 22;123(16):164504.
合成参考文献
摘要:Kostikov, R. R.; Khlebnikov, A. F.; Sokolov, V. V., Science of Synthesis, (2010) 47, 780. 摘要:Witt, D., Science of Synthesis Knowledge Updates, (2011) 3, 317. 摘要:de Figueiredo, R. M., Science of Synthesis: Knowledge Updates, (2024) 2, 278. 摘要:Tang, R.-Y., Science of Synthesis: Knowledge Updates, (2024) 1, 364.