CAS: 329-59-9; Methyl 4-Fluoro-3-Nitrobenzoate

上下游产品

CAS号453-71-4 4-氟-3-硝基苯甲酸 | CAS号18107-18-1 (三甲硅烷)重氮甲烷 | CAS号74-88-4 碘甲烷 | CAS号77-78-1 硫酸二甲酯 | CAS号67-56-1 甲醇 | CAS号149-73-5 原甲酸三甲酯 | CAS号400-94-2 3-硝基-4-氟苯甲酰氯 | CAS号79-37-8 草酰氯 | CAS号1445-45-0 原乙酸三甲酯 | CAS号14719-83-6 4-氯-3-硝基苯甲酸甲酯 | CAS号511240-22-5 3-氨基-4-(异丙氨基)苯甲酸甲酯 | CAS号3303-34-2 L-丙氨酰-L-亮氨酸 | CAS号671820-52-3 甲基3-氧代-1,2,3,4-... | CAS号369-26-6 3-氨基-4-氟苯甲酸甲酯 | CAS号188614-01-9 3-羰基-3,4-二氢-2氢-... | CAS号66315-16-0 3-氨基-4-(甲基氨基)苯羧酸甲酯 | CAS号59719-77-6 4-乙氧基-3-硝基苯甲酸 | CAS号128429-03-8 methyl 3-nitro-... | CAS号1268867-03-3 3-氯-2-(4-氟苯基)喹噁... | CAS号100596-38-1 4-[3,5-双(甲氧基羰基)...

硫酸二甲酯置于lithium Hydroxide体系中,用 四氢呋喃 作为反应溶剂,化学反应 9.0H,以78%的收率获得产物4-氟-3-硝基苯甲酸甲酯
参考文献:Benzimidazole Derivatives And Their Use As Gnrh Antagonists
标题:Benzimidazole Derivatives And Their Use As Gnrh Antagonists
摘要:本申请的主题是新的苯并咪唑衍生物,其化学式为其中a,Y,R1,R2,R3和r4代表不同的变量基团.这些产物具有gnrh(促性腺激素释放激素)的拮抗活性.该发明还涉及含有上述产物的药物组合物以及它们用于制备药物的用途.

专利信息

专利号:US-4086423-A
优先权日:1973-10-12
标题 :Process for cephem synthesis
发明人：FIRESTONE RAYMOND A; RATCLIFFE RONALD W; CHRISTENSEN BURTON G
权利人:MERCK & CO INC
摘要:Cephalosporin antibiotics of the formula: ##STR1## are produced by cycloaddition of a glycine derivative of the formula ##STR2## with a thiazine derivative of the formula ##STR3##

专利号:US-10947533-B2
优先权日:2016-05-24
标 题 :Processes for preparing phosphorodiamidate morpholino oligomers
发明人：CAI BAOZHONG; MARTINI MITCHELL; THOMAS KATIE; SHIMABUKU ROSS
权利人:SAREPTA THERAPEUTICS INC
摘要:Provided herein are processes for preparing an oligomer (e.g., a morpholino oligomer). The synthetic processes described herein may be advantageous to scaling up oligomer synthesis while maintaining overall yield and purity of a synthesized oligomer.

专利号:US-11472824-B2
优先权日:2016-05-24
标 题 :Processes for preparing phosphorodiamidate morpholino oligomers
发明人：CAI BAOZHONG; MARTINI MITCHELL; THOMAS KATIE; SHIMABUKU ROSS
权利人:SAREPTA THERAPEUTICS INC
摘要:Provided herein are processes for preparing an oligomer (e.g., a morpholino oligomer). The synthetic processes described herein may be advantageous to scaling up oligomer synthesis while maintaining overall yield and purity of a synthesized oligomer.

专利号:US-12297219-B2
优先权日:2016-05-24
标题 :Phosphorodiamidate morpholino oligomers
发明人：CAI BAOZHONG; MARTINI MITCHELL; THOMAS KATIE; SHIMABUKU ROSS
权利人:SAREPTA THERAPEUTICS INC
摘要:Provided herein are processes for preparing an oligomer (e.g., a morpholino oligomer). The synthetic processes described herein may be advantageous to scaling up oligomer synthesis while maintaining overall yield and purity of a synthesized oligomer.

专利号:CN-114516867-B
优先权日:2020-04-28
标 题 :A class of oxygen-containing five-membered heterocyclic compounds, synthesis methods, pharmaceutical compositions and uses

专利号:US-11384105-B2
优先权日:2016-05-24
标 题 :Processes for preparing oligomers
发明人：CAI BAOZHONG; MARTINI MITCHELL; SHIMABUKU ROSS; THOMAS KATIE; FRANK DIANE ELIZABETH; BESTWICK RICHARD K
权利人:SAREPTA THERAPEUTICS INC
摘要:Provided herein are processes for preparing an oligomer (e.g., a morpholino oligomer). The synthetic processes described herein may be advantageous to scaling up oligomer synthesis while maintaining overall yield and purity of a synthesized oligomer.