CAS: 4244-84-2; Ethyl 3-Aminopropanoate Hydrochloride

该化合物是一种化学化合物,其结构特征是乙酯组,该化合物包括附属于氨氨酸-氨酸的乙酯组;它是在水中溶解的白到非白晶状粉,具有血色特性;该化合物经常用于生物化学和药物研究,因为它在合成peptides和其他生物活性分子方面起着建筑构件的作用;作为盐盐类,通常比其自由基质形式更稳定和更容易处理. -氨酸本身是一种非必要的氨酸,在氨酸合成中起着关键作用,而氨酸是一种在肌肉组织中起缓冲作用的二酸;乙酸酯形态可能提高-aline的生物利用率,使其对体育营养和性能增强具有兴趣.安全数据表明,应当谨慎处理,正如许多化学物质一样,以避免潜在的刺激或不利反应.

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23583-21-3 88574-53-2 107-95-9

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上下游产品

ethyl 4-amino-4- oxobutanoate 3-azidopropionic acid ethyl ester ethanol β-alanine hydr°Chlorideethyl 3-is°Cyanatopropanoate 3-amino propanoic acid N-(N-benzyloxycarbonyl-glycyl)-β-alanine ethyl esterN-(N-benzyloxycarbonyl-glycyl)-β-alanine ethyl ester 2,3-Dioxo-4-pyrrolidincarbonsaeure-ethylester

合成工艺路线路线简述

  • 合成目标产物 Ethyl 3-Aminopropanoate Hydrochloride 主要起始原料 Ethanol And β-Alanine
  • (文献来源)合成步骤主要原料 Ethanol 和 β-Alanine
琥珀酰胺酸乙酯置于盐酸,[双(三氟乙酰氧基)碘]苯体系中,化学反应生成 Beta-丙氨酸乙酯盐酸盐
参考文献:Conversion Of Aliphatic Amides Into Amines With [i,I-Bis(Trifluoroacetoxy)Iodo]Benzene. 1. Scope Of The Reaction
标题:Conversion Of Aliphatic Amides Into Amines With [i,I-Bis(Trifluoroacetoxy)Iodo]Benzene. 1. Scope Of The Reaction
摘要:
DOI:10.1021/jo00196A031

海关参考信息

专利信息


专利号:US-4171438-A
优先权日:1975-07-23
标 题:0-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents
发明人:DOUGLAS JAMES L; HORNING DONALD E; MORRIS LEESON R
权利人:BRISTOL MYERS CO
摘要:There is described the stereoselective total synthesis of novel DELTA 2,3-1,4-morpholine-2-carboxylic acids possessing a fused beta -lactam ring in the 1,6-position and carrying a substituent cis to carbon 5 in the 7-position of the fused ring system represented by the general formula I wherein X is acylamino and Z represents optionally substituted C1-C6 alkyl, aryl or aralkyl. Also included in the invention are compounds of the above formula in which the carboxyl group at the 2-position is protected as by an easily cleavable ester group and salts of both the free acids and carboxyl-protected compounds. The compounds are potent antibacterial agents.

专利号:US-4118566-A
优先权日:1975-07-23
标 题:Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents
发明人:HORNING DONALD E; MORRIS LEESON R; DOUGLAS JAMES L
权利人:BRISTOL MYERS CO
摘要:There is described the stereoselective total synthesis of novel DELTA 2,3-1,4-morpholine-2-carboxylic acids possessing a fused beta -lactam ring in the 1,6-position and carrying a substituent cis to carbon 5 in the 7-position of the fused ring system represented by the general formula I wherein X is amino, azido or acylamido and Z represents optionally substituted C1-C6 alkyl, aryl, aralkyl or heterocyclic. Also included in the invention are compounds of formula I in which the carboxyl group at the 2-position is protected as by an easily cleavable ester group and salts of both the free acids and carboxyl-protected compounds of formula I. The compounds of formula I are potent antibacterial agents or are of use as intermediates in the preparation of such antibacterial agents.

专利号:US-8580822-B2
优先权日:2006-12-11
标 题:Compositions, synthesis, and methods of using indanone based cholinesterase inhibitors
发明人:BHAT LAXMINARAYAN; MOHAPATRA PRABHU PRASAD
权利人:BHAT LAXMINARAYAN; MOHAPATRA PRABHU PRASAD; REVIVA PHARMACEUTICALS INC
摘要:The present invention provides novel indanone derivatives which can be advantageously used for treating and/or preventing of a medical condition for which inhibition of a cholinesterase is desired.

专利号:CN-117756712-A
优先权日:2023-12-13
标 题:Synthesis of dabigatran etexilate intermediate and preparation method of impurities

专利号:US-6417195-B1
优先权日:1999-02-22
标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人:LEBL MICHAL
权利人:LION BIOSCIENCE AG
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.

专利号:US-7166619-B2
优先权日:2002-08-14
标题 :Prenylation inhibitors and methods of their synthesis and use
发明人:LI FRANCINE FEIRONG; REHDER KENNETH S; CAMPBELL MICHAEL GORDON; VISCARDI CELESTE PATRICE; STRACHAN JON-PAUL; GUO ZHENGMING
权利人:PPD DISCOVERY INC
摘要:The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
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主要参考文献

[参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1026.

合成参考文献


参考文献:10.1055/s-0033-1339760
摘要:Pal S, Sen I, Kloer D, Hall R. Synthesis of Six-Membered Cyclic Sulfonimidamides. Synthesis. 2013 Sep 10;45(21):3018–28. doi: 10.1055/s-0033-1339760.
参考文献:10.1055/s-0034-1380905
摘要:Synthesis of Glucagon Receptor Antagonist LY2409021. Synfacts. 2015 Jun 17;11(07):0677. doi: 10.1055/s-0034-1380905.
参考文献:10.1134/s1070428025601359
摘要:Zare Fekri L. Application of Fe3O4@SiO2Pr@4-hydroxy-3-methoxybenzaldehyde/bis(thioglycolic acid) as a Green, Efficient, and Magnetically Recoverable Catalyst for the Synthesis of Thiazolidinones. Russ J Org Chem. 2025 Oct;61(10):1968–76. doi: 10.1134/s1070428025601359.
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