合成目标产物 Methyl Oxalyl Chloride 主要起始原料 Methanol And Oxalyl Chloride
(文献来源)合成步骤主要原料 Methanol 和 Oxalyl Chloride
Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于氯化亚砜体系中,化学反应生成 甲基戊酰氯 参考文献:The Ring Closure Of N-Alkoxalyl-β-Anilinopropionic Acids 标题:The Ring Closure Of N-Alkoxalyl-β-Anilinopropionic Acids 摘要: DOI:10.1021/ja01175A083
专利号:US-2022220061-A1 优先权日:2019-05-09 标 题:Process for the synthesis of the ionic liquid tetraoctylammonium di(2-ethylhexyl)-oxamate (il-5), product obtained and its use in selective metal extraction 发明人:ARRIEGAS ESTEVÃO CORREIA LEAL JOÃO PAULO; DA CUNHA OLIVEIRA FIGUEIRA CARRETAS JOSÉ MANUEL; MARIA CRUZ ADELAIDE; DE JESUS MARIA LEONOR MARIA; RAMOS BATISTA MONTEIRO BERNARDO 权利人:INST SUPERIOR TECNICO 摘要:a) The present invention falls within the area of the synthesis of ionic liquids, namely it concerns a process of synthesis of the ionic liquid tetraoctylammonium di(2-ethylhexyl)-oxamate (IL-5) with a high degree of purity and its use in the extraction and selective separation of metals, namely lanthanides. Thus, it is the object of the present invention, a process for the synthesis of a pure ionic liquid using in its constitution only the elements carbon, hydrogen, oxygen and nitrogen (CHON), assuming itself as a “greenâ€? alternative in the recovery of metals, thus reducing the environmental impact in the way they are recovered, as well as the guarantee of a more efficient extraction of these metals.
专利号:WO-2018154596-A1 优先权日:2017-02-22 标 题 :Process for synthesis of tiotropium bromide monohydrate 发明人:REDDY G NITHUN; REDDY G SAMHITHA; REDDY G MADAALASA; RAMANI M; REDDY G PRATAP 权利人:GBR LABORATORIES PVT LTD; RACHANA PHARMA TECH 摘要:Provided herein is a process for synthesis of tiotropium bromide wherein the coupling of scopine with 2, 2-dithienyl glycolate is achieved by a two step process under mild conditions.
专利号:US-6608196-B2 优先权日:2001-05-03 标题 :Process for solid supported synthesis of pyruvate-derived compounds 发明人:WANG BING; JANAGANI SATYANARAYANA; CALLAWAY WYETH B; SESSLER JONATHAN L 权利人:GALILEO PHARMACEUTICALS INC 摘要:Provided are processes for synthesizing structurally diverse pyruvate-derived compounds using a parallel approach on a solid phase support. Examples of such a solid phase support include resins which have also been used in solid phase peptide synthesis.
专利号:EP-2038260-B1 优先权日:2006-06-16 标题:Stereoselective synthesis of (s)-1-methyl-3-phenylpiperazine 发明人:VAN VLIET MICHIEL CHRISTIAN ALEXANDER; KEMPERMAN GERARDUS JOHANNES; SCHREUDER GOEDHEIJT MARCEL 权利人:ORGANON NV 摘要:This invention provides for a compound according to Formula (1), wherein R1 is methyl, ethyl, n-propyl, isopropyl, benzyl or 2-haloethyl and the use thereof in a method to prepare (S)-1-methyl-3-phenylpiperazine by enzymatic hydrolysis of the compound, followed by separation and cleavage of the oxalamic groups, whereby the protease of Streptomyces griseus is used as enzyme for the enzymatic hydrolysis.
专利号:US-9265773-B2 优先权日:2011-09-08 标题 :Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases 发明人:MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; HE SHUWEN; DAI XING; LIU HONG; LAI ZHONG; LONDON CLARE; XIAO DONG; ZORN NICOLAS; NARGUND RAVI 权利人:MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; HE SHUWEN; DAI XING; LIU HONG; LAI ZHONG; LONDON CLARE; XIAO DONG; ZORN NICOLAS; NARGUND RAVI; MERCK SHARP & DOHME; MSD ITALIA SRL 摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
专利号:US-9676783-B2 优先权日:2008-10-22 标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds 发明人:HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN 权利人:ARRAY BIOPHARMA INC 摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.