CAS: 1690-72-8; Methyl 1-Methylpiperidine-3-Carboxylate

相似化合物

148763-41-1 88466-76-6 174543-74-9

上下游产品

CAS号63-75-2 槟榔碱 | CAS号50-00-0 甲醛 | CAS号50585-89-2 3-哌啶甲酸甲酯 | CAS号67-56-1 甲醇 | CAS号4685-10-3 Iodonicot | CAS号74-88-4 碘甲烷 | CAS号93-60-7 烟酸甲酯 | CAS号77-78-1 硫酸二甲酯 | CAS号5169-78-8 替培啶

3-哌啶甲酸置于甲醇,硫酸体系中,用 水 用作溶剂,化学反应 0.25H,反应生成1-甲基-3-哌啶甲酸甲酯
参考文献: Carboxamide Inhibitors Of Irak4 Activity[fr] Carboxamides Utilisés Comme Inhibiteurs De L'Activité De L'Irak4
标题: Carboxamide Inhibitors Of Irak4 Activity[fr] Carboxamides Utilisés Comme Inhibiteurs De L'Activité De L'Irak4
摘要:本发明涉及式(I)的irak4的羧酰胺抑制剂,并提供包含这种抑制剂的组合物,以及用于治疗irak4介导或相关疾病或疾病的方法.

专利信息

专利号:US-5714466-A
优先权日:1993-06-22
标题:Method of using acylation stimulating protein
发明人：SNIDERMAN ALLAN D; CIANFLONE KATHERINE
权利人:UNIV MCGILL
摘要:The present invention relates to a method to determine the amount of ASP protein, a functional derivative or a functional fragment thereof in a plasma sample, wherein the ASP protein comprises the following amino acid sequence: SEQ ID NO: 1 wherein the functional derivative comprises at least one selected from the group consisting of one or more amino acid substitution, one or more amino acid deletion and one or more amino acid addition with the proviso that the functional derivative has a biological activity functionally equivalent to ASP, and the functional fragment comprises part of the ASP amino acid sequence and has a biological activity functionally equivalent to ASP; the method comprises the steps of: a) eluting the plasma sample on a column; b) measuring the amount of the ASP protein, functional derivative or functional fragment thereof present in said sample by an immunoassay with antibodies specific against one or more sites on C3a. The present invention also relates to the use of any antagonist of the ASP protein, functional derivative or functional fragment thereof for the inhibition of triglyceride synthesis in a patient, wherein the antagonist is selected from the group consisting of inhibitors of the alternate complement pathway.

专利号:US-8703813-B2
优先权日:2008-10-31
标题 :Compound with spiro chiral carbon backbone, preparation method thereof, and pharmaceutical composition containing the same
发明人：Kang heon-joong; RHO JUNG-RAE; HONG JEONG-HO; PARK SEUNG-BUM; SHIN CHAN-SOO; LEE JAE-HWAN; HONG JUN-YOUNG; KIM EUN-O; KIM JEONG-AH; OH SANG-MI
权利人:Kang heon-joong; RHO JUNG-RAE; HONG JEONG-HO; PARK SEUNG-BUM; SHIN CHAN-SOO; LEE JAE-HWAN; HONG JUN-YOUNG; KIM EUN-O; KIM JEONG-AH; OH SANG-MI; SNU R&DB FOUNDATION
摘要:Provided is a compound having a spiro chiral carbon backbone, a stereoisomer thereof, an enantiomer thereof, an in vivo hydrolysable precursor thereof, or a pharmaceutically acceptable salt thereof. The compound having the spiro chiral carbon backbone has excellent osteoblast differentiation activity, mast cell inhibitory activity, and fatty acid synthesis inhibitory activity in the liver. Therefore, the compound can be expected to play an innovative role in treatment of osteoporosis, fatty liver, and obesity.