CAS: 4931-66-2; Methyl (S)-(+)-2-Pyrrolidone-5-Carboxylate

相似化合物

54571-66-3 64700-65-8 108963-96-8

上下游产品

CAS号98-79-3 L-焦谷氨酸 | CAS号67-56-1 甲醇 | CAS号149-87-1 DL-焦谷氨酸 | CAS号77-76-9 2,2-二甲氧基丙烷 | CAS号108963-94-6 methyl L-1-(4-n... | CAS号7664-93-9 硫酸 | CAS号7757-82-6 元明粉 | CAS号75857-94-2 1-Benzyl 2-meth... | CAS号88668-76-2 L-Norvaline, 5-... | CAS号108963-96-8 B°C-L-焦谷氨酸甲酯 | CAS号106191-02-0 (S)-5-(((叔丁基二甲基... | CAS号42435-88-1 (S)-1-甲基-5-氧代吡咯... | CAS号364750-80-1 (2S,4R)-1-(叔丁氧羰... | CAS号59936-29-7 (S)-1-叔-丁基-2-甲基... | CAS号145414-30-8 (5S)-5-(azidome... | CAS号51693-17-5 (S)-(+)-5-羟甲基-2... | CAS号64700-65-8 (R)-(-)-2-吡咯酮-5-甲酸甲酯 | CAS号4931-66-2 L-焦谷氨酸甲酯 | CAS号4931-68-4 L-焦谷氨酸丁酯 | CAS号84285-34-7 butyl-5-oxopyro...

L-焦谷氨酸置于草酰氯,糖精体系中,用 二氯甲烷 作为反应溶剂,化学反应 2.58H,反应生成 L-焦谷氨酸甲酯
参考文献:吡咯烷酮的研究.焦谷氨酰氯的改进合成
标题:吡咯烷酮的研究.焦谷氨酰氯的改进合成
摘要:摘要 焦谷氨酸三甲基甲硅烷基酯与草酰氯在室温下反应容易反应生成焦谷氨酰氯.这种通过其他方法难以获得的不稳定化合物适用于制备焦谷氨酸酯和酰胺.
DOI:10.1080/00397919408010572

专利信息

专利号:US-2006074259-A1
优先权日:2004-10-01
标 题:Process for the enzymatic synthesis of pyroglutamic esters
发明人：PASCALY MATTHIAS; THUM OLIVER
权利人:GOLDSCHMIDT GMBH
摘要:A process for the preparation of compounds according to the general formula (I), n nin which R is a hydrocarbon radical of an alcohol, wherein one or more alcohols of the general formula (II) n nR—OH  (II)n nin which R is as defined above, are esterified and/or transesterified without using significant amounts of solvents, preferably without solvents, preferably under reduced pressure at temperatures below 100° C. in the presence of enzymes from the class of hydrolases with a compound according to the general formula (III), n n nin which R 1 is either hydrogen or a linear or branched alkyl or alkenyl group having 1 to 3 carbon atoms is provided.

专利号:US-8143416-B2
优先权日:2004-08-31
标题 :Alternative synthesis of renin inhibitors and intermediates thereof
发明人：SEDELMEIER GOTTFRIED; MICKEL STUART JOHN; RUEEGER HEINRICH
权利人:SEDELMEIER GOTTFRIED; MICKEL STUART JOHN; RUEEGER HEINRICH; NOVARTIS AG
摘要:The present invention relates to synthetic routes to prepare a compound of the formula n nwherein R 1 is halogen, C 1-6 halogenalkyl, C 1-6 alkoxy-C 1-6 alkyloxy or C 1-6 alkoxy-C 1-6 alkyl; R 2 is halogen, C 1-4 alkyl or C 1-4 alkoxy; R 3 and R 4 are independently branched C 3-6 alkyl; and R 5 is cycloalkyl, C 1-6 alkyl, C 1-6 hydroxyalkyl, C 1-6 alkoxy-C 1-6 alkyl, C 1-6 alkanoyloxy-C 1-6 alkyl, C 1-6 aminoalkyl, C 1-6 alkylamino-C 1-6 alkyl, C 1-6 dialkylamino-C 1-6 alkyl, C 1-6 alkanoylamino-C 1-6 alkyl, HO(O)C—C 1-6 alkyl, C 1-6 alkyl-O—(O)C—C 1-6 alkyl, H 2 N—C(O)—C 1-6 alkyl, C 1-6 alkyl-HN—C(O)—C 1-6 alkyl or (C 1-6 alkyl) 2 N—C(O)—C 1-6 alkyl; or a pharmaceutically acceptable salt thereof as well as key intermediates obtained when following these routes as well as their preparation.

专利号:EP-3174849-B1
优先权日:2014-07-30
标 题:Synthesis of pyrrolidine derivatives

专利号:US-2008058528-A1
优先权日:2006-07-20
标题 :Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile

专利号:US-4975441-A
优先权日:1988-03-23
标 题:Lactams, their synthesis and use in cosmetic compositions
发明人：GIBSON WALTER T
权利人:UNILEVER PATENT HOLDINGS
摘要:A composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth comprises: (i) a chemical inhibitor of glycosidase activity chosen from lactams having the structure: where A<1> and A<6> are -H, -CH3, - @@0, -CH2OT or @@@0 A<1> and A<6> being the same or different, and at least one of which being the group: @ @@o in a lactam ring; and where Q is -OT min , -NHT min or a lactam linkage to A<1> or A<6>; the Q groups being the same or different, and at least one of which is involved in a lactam linkage; and where T is the same or different and is chosen from -H, -CpH2p+1 or a metal ion, T min is -H or -COCpH2p+1, and p is an integer of from 1 to 22; provided that: where any of the Q groups is -OT min or -NHT min , then that group or groups can be of either stereochemical configuration with respect to the plane of the ring; and (ii) a cosmetically acceptable vehicle for the chemical inhibitor. Certain novel lactams are also claimed.

专利号:CA-2657930-A1
优先权日:2006-07-20
标 题 :Synthesis of (2s,5r)-5-ethynyl-1-{n-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile