CAS: 1972-71-0; 2-Hydroxy-N-(2-Hydroxybenzoyl)Benzamide

上下游产品

phenyl Salicylate salicylamide phosgene hydrogenchloride2-(o-hydroxyphenyl)-4-oxo-1,3-benzoxazinium perchlorate 2-(o-acetoxyphenyl)-4-oxo-1,3-benzoxazinium perchlorate deferasirox 3,5-bis-(o-hydroxyphenyl)-1H-1,2,4-triazole

水杨酸乙酯置于磷酸酐,乙醇,氨体系中,化学反应生成2-羟基-N-(2-羟基苯基)苯甲酰胺
参考文献:Spilker,Chemische Berichte,1889,Vol. 22,P. 2768
标题:Spilker,Chemische Berichte,1889,Vol. 22,P. 2768

专利信息

专利号:US-8907083-B2
优先权日:2010-08-25
标题 :Process for the preparation, of 2-(2-hydroxyphenyl)-benz [1, 3] oxazin-4-one and its use for preparation of 4-[3, 5-bis (2-hydroxyphenyl)-IH-I, 2, 4-triazolTI-yl] benzoic acid
发明人：DAVULURI RAMAMOHAN RAO; PONNAIAH RAVI; BATTHNI GURUSWAMY; MEDIDA CHANDRA MURTHY V R; DUMMU SANTHOSH
权利人:DAVULURI RAMAMOHAN RAO; PONNAIAH RAVI; BATTHNI GURUSWAMY; MEDIDA CHANDRA MURTHY V R; DUMMU SANTHOSH; RAMAMOHAN RAO DAVULURI
摘要:The invention provides a novel process for the synthesis of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one, the process comprising of reacting the salicylic acid with salicylamide in the presence of p-toluenesulfonyl chloride, base and solvent. The use of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one in the preparation of Deferasirox is also disclosed in the invention.