CAS: 104-38-1; 1,4-Bis(2-Hydroxyethoxy)Benzene

该化合物是一种多种用途的化学化合物,主要用作聚合物,树脂和特殊化学品的合成中间体,其双功能结构以两个氢氧基组为特征,使其能够作为聚氨酯和环氧氧制剂的交叉连接剂或链扩展剂;该化合物具有极好的热稳定性和反应性,适合高性能应用;极地溶剂中的溶性进一步提高其在涂层,粘合剂和弹性体中的效用;由于硬性和灵活性的平衡结合,氢基苯乙基(2-氢氧乙基)醚有助于改进聚合物基体的机械特性和耐性.

结构式图片

相似化合物

2245-53-6 122-99-6 5897-78-9

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

[1,3]-dioxolan-2-one hydroquinone 2-chloro-ethanol sodium 4-hydroxybenzen-1-olate1,4-bis-(2-ethoxycarbonyloxy-ethoxy)-benzene 1,4-bis-(2-acetoxy-ethoxy)-benzene 1,4-bis-(2-methacryloyloxy-ethoxy)-benzene 1,6-bis-{2-[4-(2-hydroxy-ethoxy)-phenoxy]-ethoxycarbonylamino}-hexane

合成工艺路线路线简述

  • 合成目标产物 Hydroquinone Bis(2-Hydroxyethyl)Ether 主要起始原料 Ethylene Oxide And Hydroquinone
  • (文献来源)合成步骤主要原料 Ethylene Oxide 和 Hydroquinone
1,4-Phenylen-Bis-Oxyacetaldehyd置于sodium Tetrahydroborate体系中,用 乙醇 用作溶剂,以3.87 G的收率获得对苯二酚二羟乙基醚
参考文献:新核的合成及其在聚酯树枝状聚合物制备中的应用
标题:新核的合成及其在聚酯树枝状聚合物制备中的应用
摘要:已经通过还原还原性臭氧分解产物以一致的一锅方式从末端的烯丙基制备了六种由羟基基团封端的树枝状聚合物和树枝状核心,所述羟基不能被酚解或不能被氢解.一些末端烯丙基衍生物是新的,而另一些已通过新方法制备.2,2'-双(羟甲基)丙酸的众所周知的o-亚苄基衍生物被证明是顺式-立体异构体.已经制备了新的ab 3型酸酐,三(苄氧基甲基)乙酸酐.结果表明,这些核和树枝状分子可以组装成第一代和第二代均聚物和混合聚酯树枝状聚合物.
Doi:10.1016/j.Tet.2010.10.018

海关参考信息

专利信息


专利号:US-10730994-B2
优先权日:2015-06-08
标 题:Synthesis of polycarbonate siloxane diols
发明人:MAGUIRE FRANCIS P; VENKATARAMANI SRIRAM
权利人:AORTECH INT PLC; MAGUIRE FRANCIS P; VENKATARAMANI SRIRAM
摘要:The present invention provides silicon-based polycarbonates, processes for their preparation and their use in the synthesis of copolymers, in particular segmented copolymers such as polyurethanes for biomedical applications.

专利号:US-2003130433-A1
优先权日:2001-10-30
标题 :Process for the production of graft polymers
发明人:WENZ ECKHARD; BUCHHOLZ VERA; EICHENAUER HERBERT; WOLF UDO; BORN RALF-JURGEN; JANSEN ULRICH; DIETZ WOLFGANG
摘要:A process of preparing a graft polymer (e.g., an ABS graft copolymer), which involves determining the concentration of at least one reaction component during the course of the reaction by means of Raman spectroscopy, is disclosed. The process, more particularly, comprises: (a) synthesizing the graft polymer from a reaction mixture comprising reactive components (e.g., monomers such as styrene and acrylonitrile, and a graft base); (b) analyzing the reaction mixture, at intervals, during the synthesis of the graft polymer, by means of Raman spectra; (c) recording the results of the Raman spectra analysis; (d) determining the concentration of at least one of said reactive components (e.g., styrene) by means of spectral evaluation of the recorded Raman spectra; and (e) terminating the synthesis reaction of the graft polymer when the concentration of at least one of the reactive components has reached a predetermined concentration value.

专利号:US-8304409-B2
优先权日:2002-07-03
标 题:Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
发明人:EARL RICHARD A; EZAWA MAIKO; FANG XINQIN; GARVEY DAVID S; GASTON RICKY D; KHANAPURE SUBHASH P; LETTS L GORDON; LIN CHIA-EN; RANATUNGE RAMANI R; RICHARDSON STEWART K; SCHROEDER JOSEPH D; STEVENSON CHERI A; WEY SHIOW-JYI
权利人:EARL RICHARD A; EZAWA MAIKO; FANG XINQIN; GARVEY DAVID S; GASTON RICKY D; KHANAPURE SUBHASH P; LETTS L GORDON; LIN CHIA-EN; RANATUNGE RAMANI R; RICHARDSON STEWART K; SCHROEDER JOSEPH D; STEVENSON CHERI A; WEY SHIOW-JYI; NICOX SA
摘要:The invention describes novel nitrosated nonsteroidal antiinflammatory drugs (NSAIDs) and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated NSAID, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or at least one therapeutic agent. The invention also provides novel compositions comprising at least one nitrosated NSAID, and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one nitrosated NSAID, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides methods for treating inflammation, pain and fever; for treating gastrointestinal disorders; for facilitating wound healing; for treating and/or preventing gastrointestinal, renal and/or respiratory toxicities resulting from the use of nonsteroidal antiinflammatory compounds; for treating inflammatory disease states and/or disorders; and for treating and/or preventing ophthalmic diseases and/or disorders.

专利号:US-2021238374-A1
优先权日:2020-02-04
标 题 :Templated synthesis of nanovoided polymers
发明人:YE SHENG; LANDIG RENATE EVA KLEMENTINE; DIEST KENNETH ALEXANDER; OUDERKIRK ANDREW JOHN; BOWMAN CHARLES ROBERT; BOWMAN ROBERT G; HENDRICKSON WILLIAM ARTHUR; RUEB CHRISTOPHER J; PURVIS II LAFE JOSEPH; SUN WENMO; LI RYAN; YAROSHCHUK OLEG; RAO TINGLING; BOROMAND ARMAN; ZHAO CHURNING; Khaleghimeybodi Morteza
权利人:FACEBOOK TECH LLC
摘要:A method of forming a voided polymer includes forming a polymerizable composition containing a polymer precursor and a solid templating agent, forming a coating of the polymerizable composition, processing the coating to form a cured polymer material having a solid phase in a plurality of defined regions, and removing at least a portion of the solid phase from the cured polymer material to form a voided polymer layer.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:WO-2020165135-A1
优先权日:2019-02-11
标 题:Acrylic copolymer capsule designed to open up at < 90°c for controlled release of in-situ forming pu/pir catalyst
发明人:LIESE JULIA; ZHANG LI; STAFF ROLAND HINRICH; BEZIAU ANTOINE MAXIME CHARLES JOSEPH
权利人:BASF SE
摘要:The present invention relates to a catalyst useful for polyurethane or polyisocyanurate synthesis comprising an aqueous and/or alcoholic solution of lithium chloride encapsulated in a (meth)acrylic copolymer capsule shell, wherein the (meth)acrylic copolymer capsule shell is obtained or obtainable by reacting: i) 10 to 90 weight-% of a first (meth)acrylate composition comprising a polyester of (meth)acrylic acid with a C2 to C24 alkylpolyol; ii) 90 to 10 weight-% of a second (meth)acrylate composition comprising a monoester of (meth)acrylic acid with a C1 to C24 alkanol; wherein the weight-% are based on an overall weight of all (meth)acrylates of 100 weight-%. In further aspects, the invention relates to a catalytic composition comprising the catalyst and an epoxide composition; a process for preparation of an aqueous and/or alcoholic solution of lithium chloride encapsulated in a (meth)acrylic copolymer capsule shell, and also to an aqueous and/or alcoholic solution of lithium chloride encapsulated in an acrylic copolymer capsule shell obtained or obtainable from the process, as well as to the use of the catalyst or of the aqueous and/or alcoholic solution of lithium chloride encapsulated in an acrylic copolymer capsule shell obtained or obtainable from the process for the preparation of polyurethane or polyisocyanurate. The invention also relates to a polyurethane or polyisocyanurate obtained or obtainable from the reaction of at least: a) a polyisocyanate composition; b) a polyol composition; in the presence of an epoxide composition and a catalyst comprising an aqueous and/or alcoholic solution of lithium chloride encapsulated in a (meth)acrylic copolymer capsule shell, wherein the (meth)acrylic copolymer capsule shell is obtained or obtainable by reacting: i) 10 to 90 weight-% of a first (meth)acrylate composition comprising a polyester of (meth)acrylic acid with a C2 to C24 alkylpolyol; ii) 90 to 10 weight-% of a second (meth)acrylate composition comprising a monoester of (meth)acrylic acid with a C1 to C24 alkanol; wherein the weight-% are based on an overall weight of all (meth)acrylates of 100 weight-%. Furthermore, the invention relates to a process for the preparation of the polyurethane or polyisocyanurate.
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摘要:Joosten, A.; Brioche, J., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 10.
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