CAS: 137-07-5; 2-Aminobenzenethiol

上下游产品

CAS号136-95-8 2-氨基苯并噻唑 | CAS号1141-88-4 2,2'-二氨基二苯二硫醚 | CAS号95-16-9 苯并噻唑 | CAS号1155-00-6 2,2'-二硝基二苯二硫醚 | CAS号23786-14-3 4-甲氧基苯乙酸甲酯 | CAS号587-88-2 对氟苯乙酸乙酯 | CAS号1193-02-8 4-氨基苯硫酚 | CAS号52449-43-1 4-氯苯乙酸甲酯 | CAS号2876-78-0 1-萘乙酸甲酯 | CAS号14062-19-2 4-甲基苯基乙酸乙酯 | CAS号1032-98-0 3-(2-benzothiaz... | CAS号1047-61-6 Benzenecarbothi... | CAS号105602-95-7 2-benzylsulfiny... | CAS号105942-32-3 4H-1,4-benzothi... | CAS号106691-36-5 2-(3-oxo-4H-1,4... | CAS号108176-69-8 1-(2H-1,4-benzo... | CAS号106691-40-1 2-[4-(3-chlorop... | CAS号112251-27-1 2-(1H-indol-3-y... | CAS号111931-61-4 N-(1,3-benzothi... | CAS号109363-81-7 3-hydroxy-12H-c...

苯并噻唑置于potassium Hydroxide体系中,用 水,二甲基亚砜 用作溶剂,化学反应 10.0H,以83%的收率获得2-氨基苯硫醇
参考文献:一种新型 Pifa/koh 促进的合成 C2-芳酰基化苯并噻唑作为潜在药物支架的方法
标题:一种新型 Pifa/koh 促进的合成 C2-芳酰基化苯并噻唑作为潜在药物支架的方法
摘要:为了找到一种高效,便捷的合成c2-芳酰基化苯并噻唑作为潜在药物支架的方法,一种新型的[双(三氟乙酰氧基)碘]苯(Pifa)/koh协同促进2H-苯并噻唑与芳基甲基的直接开环c2-芳基酰化反应酮已被开发出来.在优化条件下,各种底物均具有耐受性,38 个示例的 C2-芳基酰化产物产率为 70-95%.基于一系列受控实验,还提出了一种合理的机制.
Doi:10.3390/molecules27030726

专利信息

专利号:US-6251689-B1
优先权日:1998-05-14
标 题:Methods for the solid phase synthesis of combinatorial libraries of benzimidazoles benzoxazoles benzothiazoles and derivatives thereof
发明人：LABORDE EDGARDO; MATSUMOTO YUKIHARU
权利人:TELIK INC
摘要:The present invention provides an efficient and versatile method for the synthesis and screening of combinatorial libraries of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof. In order to expedite the synthesis of large arrays of compounds possessing these core structures, a general methodology for solid phase synthesis of these derivatives is provided. Arrays of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof useful as peptidomimetics and for the identification of agents having antifungal, antiviral, antimicrobial, anticoagulant, and antiulcer activity, or use in the treatment of inflammation, hypertension, cancer, and other conditions can be prepared by this method.

专利号:WO-2020034022-A1
优先权日:2018-08-17
标题 :Synthesis of a fluorophore-class compound, compound produced and use thereof, process for producing white organic light emitting diodes and diodes produced
发明人：TEIXEIRA ALVES DUARTE LUIS GUSTAVO; SEVERO RODEMBUSCH FABIANO; GERMINO JOSÉ CARLOS; FALEREIRO BERBIGIER JÔNATAS; DIB ZAMBON ATVARS TERESA; MEIRA FALEIROS MARCELO
权利人:UNIV FEDERAL DO RIO GRANDE DO SUL UFRGS; UNICAMP
摘要:The present invention relates to the synthesis of a class of fluorophores developed by combining the salicylidene and benzazole classes, and to the compound produced and the technical use thereof in the form of a light emitting diode (WOLED). Said synthesis produces a compound which has advantageous optical and electronic properties and high potential for use in light emitting diodes. The present invention further relates to a process for producing white organic light emitting diodes (WOLEDs) as well as to the diodes produced.

专利号:US-2007122842-A1
优先权日:2005-11-30
标题 :Massively parallel synthesis of proteinaceous biomolecules
发明人：RAJASEKARAN JOHN J; TIWARI GUNJAN; CABEZAS EDELMIRA; FIDANZA JACQUELINE A; SUNDARARAJAN NARAYAN
权利人:RAJASEKARAN JOHN J; TIWARI GUNJAN; CABEZAS EDELMIRA; FIDANZA JACQUELINE A; SUNDARARAJAN NARAYAN
摘要:Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For example, arrays of peptides and polymers joined by peptide bonds may be fabricated in a highly multiplexed manner.

专利号:US-2007122841-A1
优先权日:2005-11-30
标题:Massively parallel synthesis of proteinaceous biomolecules
发明人：RAJASEKARAN JOHN J; TIWARI GUNJAN; CABEZAS EDELMIRA; FIDANZA JACQUELINE A; SUNDARARAJAN NARAYAN
权利人:RAJASEKARAN JOHN J; TIWARI GUNJAN; CABEZAS EDELMIRA; FIDANZA JACQUELINE A; SUNDARARAJAN NARAYAN
摘要:Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For example, arrays of peptides and polymers joined by peptide bonds may be fabricated in a highly multiplexed manner.

专利号:US-5405949-A
优先权日:1993-03-29
标题 :Process for the synthesis of glycosaminoglycans with heparin or heparan structure modified in position 2 of the α-L-iduronic-2-O-sulfate acid
发明人：UNGARELLI FABRIZIO; PIANI SILVANO
权利人:ALFA WASSERMANN SPA
摘要:A process for the synthesis of glycosaminoglycans with heparin or heparan structure modified in position 2 of the α-L-iduronic-2-O-sulfate acid in which the sulfate group is, entirely or in part, substituted with a nucleophilic group, is described. The process is carried out by treating glycosaminoglycans having heparin or heparan structure with a nucleophilic reagent in alkaline solution.

专利号:US-9499578-B2
优先权日:2005-12-29
标题 :Massively parallel synthesis of biopolymeric arrays
发明人：RAJASEKARAN JOHN J; CABEZAS EDELMIRA; FIDANZA JACQUELINE A; TIWARI GUNJAN
权利人:RAJASEKARAN JOHN J; CABEZAS EDELMIRA; FIDANZA JACQUELINE A; TIWARI GUNJAN; INTEL CORP
摘要:Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For example, arrays of branched peptides and polymers joined by peptide bonds may be fabricated in a highly multiplexed manner.