CAS: 3964-57-6; Methyl 3-Chloro-4-Hydroxybenzoate

上下游产品

3-氯-4-羟基苯甲酸 3-Chloro-4-Hydroxybenzoic Acid 3964-58-7
3-氯-4-羟基苯甲醛 4-Hydroxy-3-Chlorobenzaldehyde 2420-16-8
对羟基苯甲酸甲酯 Methyl 4-Hydroxybenzoate 99-76-3
3’-氯-4’-羟基苯乙酮 3-Chloro-4-Hydroxy-Acetophenone 2892-29-7
对羟基苯甲酸 4-Hydroxy-Benzoic Acid 99-96-7

3-氯-4-羟基苯甲酸 以87%的收率获得3-氯-4-羟基苯甲酸甲酯
参考文献:Benzopyran Derivatives Having Leukotriene-Antagonistic Action
标题:Benzopyran Derivatives Having Leukotriene-Antagonistic Action
摘要:本发明涉及具有苄氧甲基,3-苯基丙基或其他芳基取代基的新型4-氧代-4H-1-苯并吡喁化合物,其位于它们的8位.这些化合物显示出白三烯拮抗活性.这些化合物具有非常好的口服吸收特性.本发明的化合物可用作抗炎和抗过敏药物,并用于心血管疾病的治疗.

专利信息

专利号:US-9388147-B2
优先权日:2009-11-13
标题 :Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
发明人：MARTINBOROUGH ESTHER; BOEHM MARCUS F; YEAGER ADAM RICHARD; TAMIYA JUNKO; HUANG LIMING; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TIMONY GREGG ALAN; BROOKS JENNIFER L; PEACH ROBERT; SCOTT FIONA LORRAINE; HANSON MICHAEL ALLEN
权利人:RECEPTOS INC; CELGENE INTERNAT II SÃ RL
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:US-2009264648-A1
优先权日:2008-01-14
标题:Synthesis of pyrazoles
发明人：CHEW WARREN; WANG ZHENG; CHEAL GLORIA; BERTRAND MARTIAL; POTOSKI JOHN; MIRMEHRABI MAHMOUD; NENCINI ARIANNA; ZANALETTI RICCARDO
权利人:WYETH CORP; SIENA BIOTECH SPA
摘要:The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate α7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.

专利号:WO-2009091832-A1
优先权日:2008-01-14
标题 :Synthesis of pyrazoles

专利号:US-11299484-B2
优先权日:2018-10-10
标 题 :Inhibiting fatty acid synthase (FASN)
发明人：MARTIN MATTHEW W; ZABLOCKI MARY-MARGARET; MENTE SCOT; DINSMORE CHRISTOPHER; WANG ZHONGGUO; ZHENG XIAOZHANG
权利人:FORMA THERAPEUTICS INC
摘要:The present disclosure is directed to inhibitors of FASN. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of FASN. For instance, the disclosure is concerned with compounds and compositions for inhibition of FASN, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of FASN, and methods of synthesis of these compounds.

专利号:BR-122018077504-B1
优先权日:2009-11-13
标题 :METHODS FOR SYNTHESIS OF SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS

专利号:EP-3406142-B1
优先权日:2009-11-13
标题:Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis