CAS: 1984-15-2; Methylenediphosphonic Acid

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16001-93-7 87591-00-2 34162-79-3

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CAS号1660-94-2 四乙基亚甲基二磷酸酯 | CAS号1660-95-3 四异丙基亚甲基二磷酸酯 | CAS号6997-56-4 Methandiphospho... | CAS号1499-29-2 亚甲基双膦酰二氯 | CAS号16001-93-7 亚甲基二磷酸四甲酯 | CAS号1660-94-2 四乙基亚甲基二磷酸酯 | CAS号1499-29-2 亚甲基双膦酰二氯

Methylenebisphosphonic Acid Tetrakis(Trimethylsilyl) Ester置于甲醇体系中,化学反应 16.0H,反应生成亚甲基二磷酸
参考文献:Synthèse Et étude Comparée Des Propriétés Complexantes De Dérivés De L'Acide Methylène Diphosponique
标题:Synthèse Et étude Comparée Des Propriétés Complexantes De Dérivés De L'Acide Methylène Diphosponique
摘要:摘要 合成了具有两个不等价磷原子的亚甲基二膦酸 (Mdp) 的两种原始酸衍生物:[(硫代膦酸酯)-甲基]膦酸 (Mdps) 和 [(异丙酰氨基膦酸酯)-甲基] 膦酸 (Mdpn) . 一项电位研究允许定义在碱性介质中 Mdp 和镁 (II) 之间形成的复合物的化学计量,31P NMR 研究证明了这种 Mdpmg2+ 复合物的不对称结构.Black Eriochrome T 和镁 (II) 之间的配位平衡的位移允许比较 Mdp,Mdps 和 Mdpn 与阳离子 Mg2+ 的配位强度.
Doi:10.1080/10426500008042097

专利信息

专利号:WO-9902264-A1
优先权日:1997-07-11
标题:Membrane and method for synthesis of hydrogen peroxide
发明人：MCINTYRE JAMES A; SANDERS EDGAR S JR; MAHONEY ROBERT D; WEBB STEVEN P; MURCHISON CRAIG B; HAYES DAVID A
权利人:DOW CHEMICAL CO; MCINTYRE JAMES A; SANDERS EDGAR S JR; MAHONEY ROBERT D; WEBB STEVEN P; MURCHISON CRAIG B; HAYES DAVID A
摘要:This invention is a membrane which is useful for the synthesis of hydrogen peroxide from hydrogen and oxygen. The membrane has a hydrogen contact side and an oxygen contact side and comprises a porous hydrophobic catalyst layer facing the oxygen contact side and a gas flux control layer facing the hydrogen contact side. The gas flux control layer is positioned between the hydrogen contact side and the porous hydrophobic catalyst layer such that the flux of hydrogen may be controllably delivered to the porous hydrophobic catalyst layer. The membrane and method may be used to controllably synthesize hydrogen peroxide directly from hydrogen and oxygen without the use of organic solvents or complex equipment for ionic and electrical transport.

专利号:US-6909010-B2
优先权日:2001-04-11
标题:Facile synthesis of symmetric esters of alkylenebisphosphonic acids
发明人：HERLINGER ALBERT W; STEPINSKI DOMINIQUE C
权利人:UNIV LOYOLA CHICAGO
摘要:A facile synthesis of symmetric esters of C 1 -C 10 alkylenebisphopsphonic acids is disclosed in which a C 1 -C 10 alkylenebis(phosphonic dichloride) is reacted with an alcohol in the presence of a catalytic amount of 1H-tetrazole and a base in an aprotic solvent to form a first reaction mixture. The first reaction mixture is maintained for a time period sufficient to form a C 1 -C 10 alkylenebis(chloro ester phosphonate) that is reacted under basic conditions with an excess of a hydroxylated compound to form a second reaction mixture that is itself maintained for a time period sufficient to form a C 1 -C 10 alkylenebis(ester phosphonate) partial ester, homoleptic tetraester or mixed tetraester. The material so formed can be recovered or used as is.

专利号:US-2004044225-A1
优先权日:2001-06-01
标 题:Chiral and achiral synthesis of 2-acyl substituted chromanes and their derivatives
发明人：KANTER JAMES; MARLOWE CHARLES; PANDEY ANJALI; MULLINS JOHN J G; SCARBOROUGH ROBERT; BUTKE GREG; JACOBSON BARRY; WALKER DEREK
摘要:Disclosed are processes for producing a (2S) or (2R) 4-oxo-chroman-2-yl acyl compounds and chroman-2-yl acyl compounds, esters or amides thereof as well as derivatives thereof. Such processes may involve chiral synthesis or achiral synthesis, preferably coupled with a resolution procedure. Such compounds, particularly (2S) or (2R) acetic acid esters, are useful intermedates for producing platelet aggregation inhibitors and/or are themselves potent platelet aggregation inhibitors. Further disclosed are processes for making derivatives of such substantially pure, or enhanced compositions of single (2R) or (2S) enantiomer intermediates or processes for producing final products or salts from such desired enantiomers.

专利号:US-6147245-A
优先权日:1998-07-13
标题:Preparation and use of α-Keto Bisphosphonates
发明人：MCKENNA CHARLES E; KASHCMIROV BORIS A
权利人:UNIV SOUTHERN CALIFORNIA UNIVE
摘要:A unique method for the synthesis of substantially pure α-keto bisphosphonate esters and the usage of these esters in reactions with C, N, O, or P nucleophiles for synthesis of α-functionalized bisphosphonates. The method starts with a reaction mixture formed of an α-diazo methanediphosphonate ester, including tert-butylchlorite, a polar aprotic organic solvent, and an effective amount of water. After synthesis is complete, a water trapping reagent may be added to remove any excess water. The present invention provides a versatile pathway to new α-substituted bisphosphonate derivatives and could be readily adapted to combinatorial drug discovery synthetic strategies. The α-keto bisphosphonate esters can be converted to the corresponding acids by acid hydrolysis or mild silyldealkylation.

专利号:US-2023078498-A1
优先权日:2020-02-07
标题 :Targeted Translation of RNA with CRISPR-Cas13 to Enhance Protein Synthesis
发明人：ANDERSON DOUGLAS MATTHEW
权利人:UNIV ROCHESTER
摘要:The present disclosure provides proteins, nucleic acids, systems and methods for enhancing the synthesis of a protein.

专利号:US-2014378538-A1
优先权日:2011-12-14
标 题:Methods of responding to a biothreat
发明人：BANCEL STEPHANE
权利人:MODERMA THERAPEUTICS INC
摘要:The present disclosure provides for devices, in particular mobile devices, which may be used in the synthesis of modified nucleic acid molecules, in particular modified mRNA molecules. The device for making the modified nucleosides, modified nucleotides and modified nucleic acids (e.g., mRNA) disclosed herein may be mobile devices comprising at least one sample block for insertion of one or more sample vessels, a device base with electronic control units for the sample block, a voltage supply, and one or more reagent(s) for the synthesis of at least one nucleic acid.