CAS: 2051-95-8; 3-Benzoylpropionicacid

上下游产品

piperidine malic acid benzaldehyde (2E)-but-2-enedioic acid 1-morpholino-4-phenylbutane-1,4-dione H-pyridazin-3-one2-(1-methyl-[4]piperidyl)-6-phenyl-2H-pyridazin-3-one H-furan-2-one3-furfurylidene-5-phenyl-3H-furan-2-one 1-methyl-3-(2-oxo-5-phenyl-furan-3-ylidene)-indolin-2-one

反式-3-苯甲酰丙烯酸置于钯 氢气体系中,用 甲醇 用作溶剂,化学反应 2.0H,以100%的收率获得3-苯丙烯溴酸酯
参考文献:新型细分散钯催化剂在丝素蛋白上的高化学选择性加氢方法:其制备及活性
标题:新型细分散钯催化剂在丝素蛋白上的高化学选择性加氢方法:其制备及活性
摘要:通过将丝素蛋白浸入pd(oac)2的meoh溶液中2天(在ar气氛下)至4天(在空气中),制备钯-丝蛋白复合物(pd / Fib ).Pd(oac)2逐渐被丝蛋白吸收,并在室温下以甲醇作为还原剂快速还原丝蛋白缀合的pd(oac)2,成为pd(0)络合物.在芳族酮和醛,卤化物,N-Cbz保护基和苄基酯的存在下,Pd / Fib催化的乙炔,烯烃和叠氮化物的化学选择性加氢反应很容易使用pd / C或pd / C(en)作为催化剂进行氢化.
Doi:10.1016/j.Tet.2004.11.080

专利信息

专利号:US-11548838-B2
优先权日:2021-02-02
标 题:Process for synthesis of polyhydrocarbons as heat transfer agents
发明人：MANDAL TANMAY; VANKUDOTH KRISHNA; SARASWAT MANISHA; ARORA AJAY KUMAR; KAGDIYAL VIVEKANAND; SAXENA DEEPAK; RAMAKUMAR Sankara Sri Venkata
权利人:INDIAN OIL CORP LTD
摘要:The present invention provides a one-pot process of synthesis of phenyl naphthalene compounds that are employed as heat transfer agents. More particularly, the present invention provides a process of preparation of 1-phenylnaphthalene and 2-methyl-1-phenylnaphthalene using refinery spent catalyst. These molecules are known for application as synthetic heat transfer fluids that deliver outstanding performance and thermal stability at continuously high operating temperatures. The reaction is carried out in aqueous medium using a spent catalyst which is a palladium based charcoal catalyst as obtained from various refinery processes. Further, the present invention provides a heat resistant formulation using the synthesized polyhydrocarbons, wherein the formulation is optimized with a free radical scavenger.

专利号:US-6921839-B2
优先权日:2000-08-29
标 题:Synthesis of N,N-dimethyl-3-(4-methyl) benzoyl propionamide a key intermediate of zolpidem
发明人：KUMAR YATENDRA; PRASAD MOHAN; NATH ASOK
权利人:RANBAXY LAB LTD
摘要:The present invention relates to an improved and industrially advantageous process for the preparation of N,N-dimethyl-3-(4-methyl)benzoyl propionamide of Formula I, n n nwhich is a key intermediate in the synthesis of zolpidem hemitartrate, a non-benzodiazepine hypnotic agent. The process includes reacting 3-(4-methyl)-benzoyl propionic acid of Formula IV, with alkyl chloroformate or pivaloyl chloride to get a mixed anhydride of Formula V; and reacting the mixed anhydride of Formula V with dimethylamine of Formula VI to get the N,N-dimethyl-3-(4-methyl)benzoyl propionamide of Formula I.

专利号:US-2024124910-A1
优先权日:2021-02-02
标题:Ribosome-mediated polymerization of novel chemistries
发明人：JEWETT MICHAEL CHRISTOPHER; LEE JOONGOO; ANSLYN ERIC V; CORONADO JAIME; LIM JONGDOO
权利人:UNIV NORTHWESTERN; UNIV TEXAS
摘要:Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

专利号:US-6214987-B1
优先权日:1994-09-02
标 题 :Compositions for enzyme catalyzed template-independent formation of phosphodiester bonds using protected nucleotides
发明人：HIATT ANDREW C; ROSE FLOYD
权利人:HIATT ANDREW C; ROSE FLOYD D
摘要:A method for the stepwise creation of phosphodiester bonds between desired nucleosides resulting in the synthesis of polynucleotides having a predetermined nucleotide sequence by preparing an initiation substrate containing a free and unmodified 3'-hydroxyl group; attaching a mononucleotide selected according to the order of the predetermined nucleotide sequence to the 3'-hydroxyl of the initiating substrate in a solution containing a catalytic amount of an enzyme capable of catalyzing the 5' to 3' phosphodiester linkage of the 5'-phosphate of the mononucleotide to the 3'-hydroxyl of the initiating substrate, wherein the mononucleotide contains a protected 3'-hydroxyl group, whereby the protected mononucleotide is covalently linked to the initiating substrate and further additions are hindered by the 3'-hydroxyl protecting group. Methods in which a mononucleotide immobilized on a solid support is added to a free polynucleotide chain are also disclosed.

专利号:US-5872244-A
优先权日:1994-09-02
标 题:3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds
发明人：HIATT ANDREW C; ROSE FLOYD
权利人:HIATT ANDREW C; ROSE FLOYD D
摘要:A method for the stepwise creation of phosphodiester bonds between desired nucleosides resulting in the synthesis of polynucleotides having a predetermined nucleotide sequence by preparing an initiation substrate containing a free and unmodified 3'-hydroxyl group; attaching a mononucleotide selected according to the order of the predetermined nucleotide sequence to the 3'-hydroxyl of the initiating substrate in a solution containing a catalytic amount of an enzyme capable of catalyzing the 5' to 3' phosphodiester linkage of the 5'-phosphate of the mononucleotide to the 3'-hydroxyl of the initiating substrate, wherein the mononucleotide contains a protected 3'-hydroxyl group, whereby the protected mononucleotide is covalently linked to the initiating substrate and further additions are hindered by the 3'-hydroxyl protecting group. Methods in which a mononucleotide immobilized on a solid support is added to a free polynucleotide chain are also disclosed.

专利号:US-5763594-A
优先权日:1994-09-02
标 题:3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds
发明人：HIATT ANDREW C; ROSE FLOYD
权利人:HIATT ANDREW C; ROSE FLOYD D
摘要:A method for the stepwise creation of phosphodiester bonds between desired nucleosides resulting in the synthesis of polynucleotides having a predetermined nucleotide sequence by preparing an initiation substrate containing a free and unmodified 3'-hydroxyl group; attaching a mononucleotide selected according to the order of the predetermined nucleotide sequence to the 3'-hydroxyl of the initiating substrate in a solution containing a catalytic amount of an enzyme capable of catalyzing the 5' to 3' phosphodiester linkage of the 5'-phosphate of the mononucleotide to the 3'-hydroxyl of the initiating substrate, wherein the mononucleotide contains a protected 3'-hydroxyl group, whereby the protected mononucleotide is covalently linked to the initiating substrate and further additions are hindered by the 3'-hydroxyl protecting group. Methods in which a mononucleotide immobilized on a solid support is added to a free polynucleotide chain are also disclosed.